Dr. French's Review Sesh Flashcards
*** DON’T CHOOSE ISOPROTERANOL AS AN ANSWER CHOICE***
just fyi!
Digoxin binds to the same site as ____.
K+
What is the most commonly used class III antiarrhythmic drug?
amiodarone
The Beta-1 receptor normally mediates _____.
the HR and inotropy
The alpha-1 thru AT-1 receptors normally mediate ____.
the preload and afterload
*** DON’T CHOOSE NITRIDE AS A CHOICE ON THE EXAM***
just sayin!
If K+ goes down in someone’s labs, you could blame the ____ drugs. If K+ goes up, you could attribute it to _____ drug.
down = loop diuretics or thiazides b/c they’re K+ wasting up = aldosterone antagonists b/c they’re K+ sparing (ACE inhibitors and ARBs)
What does digoxin do to the cardiac AP in a good, safe dose?
the Na/K pump is blocked, so Ca++ doesn’t leave the cell as much via the NCX exchanger and this increases contractivity and inotropy
How do you treat premature ventricular contractions (PVCs)?
usually none- but maybe a beta blocker
ACE inhibitors end in ____.
-pril
Name 3 inotropes.
- dobutamine 2. mirinone 3. digoxin
What vasodilator is prescribed? To whom?
hydralazine PLUS isosorbide dinitrate (nitrates) in black pts
If the tachyarrhythmia is at or above the AV node, use _____ control drugs.
rate
What does amiodarone do?
it blocks K+ repolarization and phase 0 Na+
Antiarrythmic drugs can either be ____ or ____.
rate control; rhythm control
What can high intracellular Ca++ trigger?
late delayed afterpolarizations
What is the tx for chronic supraventricular tachycardia (SVT)?
slow conduction or catheter ablation
In HF, the heart has INCREASED or DECREASED lusitropy?
DECREASED - the heart is stiffer in HF
What receptor normally mediates the preload?
alpha-1 thru AT1
____ (drug) binds to the same site as K+.
Digoxin
____ is the drug of choice for acute supraventricular tachycardia.
Adenosine
A long QT interval predisposes you to _____.
Torsades de pointes
What does PVC stand for?
premature ventricular contractions
What is the most common diuretic?
furosemide
When would you add an aldosterone antagonist to therapy?
if LVEF
What is the maximum K+ level you want your pt to be at?
5
What is the tx for V-fib?
defibrillation followed by epi or vasopressin and amiodarone