Drug Bug Cheat Sheet Flashcards by Sandrea Dumadag

When you see…

MSSA

Consider using…

Oral: Cephalexin, cefadroxil, dicloxacin, augmentin
IV: Cefazolin, Oxacillin, Nafcillin

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When you see…

MRSA

Consider using…

Oral: SMZ/TMP, Doxycycline, clindamycin, linezolid, tedizolid, omadacyclien, delafloxacin
(note: all oral option has IV formulas too)

IV: Vancomycin, daptomycin, telavancin, Dalbavancin, Oritavancin, Ceftaroline, Tigecycline

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When you see…

Enterococci

Consider using…

Ampicillin, then vacomycin
If VRE: linezolid, daptomycin, oritavancin, tigecycline, omadacycline, eravacycline

For cytitis only: nitrofurantoin, fosfomycin

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When you see…

Strep pyogenes or
Strep agalactiae

Consider using…

Penicillin
Amoxicillin
Clindamycin

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When you see…

Strep. Pnuemoniae or
Viridans group streptococci

Consider using…

Ceftriaxone, Levofloxacin, amoxicillin, augmentin

note: be aware of PCN and macrolide resistance

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When you see…

Listeria monocytogenes

Consider using…

Ampicillin

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When you see…

PsA

Consider using…

Oral: Cipro, levaquin, Delafloxacin

IV: Zosyn, ceftazidime, ceftazidime-avibactam, cefepime, Ceftolazine-tazobactam, cefiderocol, imipenem-cilastatin +/- relabactam, meropenem, aztreonam, AMG, polymyxins

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When you see…

E.coli, Klebsiella

Consider using..

Oral: Cephalexine, augmentin, TMP/SMZ, Cipro, levaquin, delafloxacin

For cystitis only: Nitrofurantoin, fosfmycin

IV: Ceftriaxone, unasyn, cefepime, zosyn, carbapenems

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When you see…

ESBL Producers /Drug resistance GNR

Consider using…

Carbapenems, ceftolazane-tazobactam, ceftazidime-avibactan, meropenem-vaborbactam, imipenem–cilasttain-relebactam, cefiderocol, polymixin, AMG, tigecycoline, omadacycline

For cystitis only: Nitrofurantoin, fosfomycin

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When you see..

NDM producer

Consider using…

Aztreonam + (mero/vab or CAZ/AVI)

cefiderocol

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When you see..

Carbapenem resistant GNR

Consider using…

ceftolazane-tazobactam, ceftazidime-avibactan, meropenem-vaborbactam, imipenem–cilasttain-relebactam, cefiderocol, polymixin, AMG, tigecycoline, omadacycline

For cystitis only: Nitrofurantoin, fosfomycin

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When you see..

Candida Albicans

Consider using…

Fluconazole

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When you see..

Candida Glabarata

Consider using…

Echinocandin
but can use fluconazole if susceptible

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When you see..

Candida Krusei

Consider using…

Micafungin
Anidulafingin
Caspofungin

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When you see..

Candida auris

Consider using…

Micafungin
Anidulafingin
Caspofungin

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When you see..

Aspergillus

Consider using…

Voriconazole

Amp + Flucyto

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When you see..

Stenotropomonas

Consider using…

TMP/SMZ
Levaquin
Minocycline

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When you see..

Salmonella Typhi

Consider using…

FQ
TMP/SMZ
Ceftriaxone

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When you see..

Anaerobes

Consider using…

Oral: flagyl, clindamycin, augmentin, moxifloxacin
IV: Unasyn, Zosyn, cefoxitin, Cefotetan, ertapenem, tigecycline

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When you see..

C.diff

Consider using…

PO Vancomycin, Fidoximicin

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When you see..

Atypicals

Consider using…

Macrolides
Tetracyclines
FQ

When you see..

Treponema pallidum,
Syphillis

Consider using..

PCN

When you see…

Mycobacterium Tuberculosis

Consider using…

Rifampin + isonizaide + pyrazinamide + pyridoxine + Ethambutol = RIPPE

When you see…

Mycobacterium avium (MAC)

Consider using…

Clarithromycin + ethambutol (treatment)

Azithromycin (ppx)

# When you see... PjP | Consider using:

SMZ/TMP (treatment or ppx)

# When you see... Toxoplasma Gondii | Consider using...

Pyrimethamine + Sulfadiazine + leucovorin (tx) SMZ/TPM (ppx)

# See This.... Bacterial Vaginosis | Consider This...

Flagyl

# See This.... Chlamydia | Consider This...

Doxycycline Azithromycin

# See This.... Gonorrhea | Consider This...

Ceftriaxone

# See This.... Cystitis | Consider This...

Nitrofurantoin

# See This.... ESBL E.coli Cystitis | Consider This...

Fosfomycin

# See This.... Prostatitis | Consider This...

FQ TMP/SMZ

# See This.... MSSA Bacteremia | Consider This...

Oxacillin Nafcillin Cefazolin

# See This.... MRSA Bacteremia | Consider This...

Vancomycin Linezolid Daptomycin

# See This.... Enterococcal Endocarditis | Consider This...

Cetriaxone HD + Ampicillin

# See This.... Viridans streptococcus endocarditis | Consider This...

PCN

# See This.... Candidemia | Consider This...

Echinocandin

# See This.... Cryptococcal meningitis | Consider This...

AmphoB + Flucytosine

# See This.... Strongylodiaisis | Consider This...

Ivermectin

# See This.... Chicken Pox or shingles | Consider This...

Valacyclovir Acyclovir

# See This.... Hepatitis B | Consider This...

Tenofovir Entacavir

# See This.... Aztreonam | Consider This...

Gram negative only

# See This.... Polymixin or colistin | Consider This...

Gram negative only

# See This.... Glycopeptides | Consider This...

Gram positive only

# See This.... Ertapenem | Consider This...

Not for APE: Acinetobacter, PsA, Enterococci

# See This.... Clindamycin | Consider This...

Not for B.frag

# See This.... PO Vancomycin , PO Fidoximicin | Consider This...

C.diff only

# See This.... Tigecycline, omadacycline, eravacycline | Consider This...

MP3 Moraganella Providencia PsA Proteus

# See This.... Rifampin | Consider This...

not for monotherapy

# See This.... Fluconazole | Consider This...

Not for candida Krusei