Drug/DOC (prim use)/prim adverse effects

Question 1

Heparin

Answer 1

Ind: IV anticoagulation
PAE: bleeding

Question 2

Enoxaprin

Answer 2

Ind: DVT/PE prophylaxis in pregnancy

Question 3

Warfarin

Answer 3

DOC:Chronic DVT/PE prophylaxis

Cat X in prenancy

Question 4

Plavix

Answer 4

Ind: platelet inhibhition in stenting

Question 5

t-PA

Answer 5

clot busting-DVT, PE

Question 6

Aminocaproic acid

Answer 6

DOC: reverse t-PA
PAE: thrombosis

Question 7

Aspirin

Answer 7

DOC: primary MI prevention
PAE: irreversibly binds PGs

Question 8

Bile resins

Answer 8

SAFEST HYPERLIPIDEMIA med

no effect on triglycerides, increases VLDL

Question 9

Niacin

Answer 9

MOST EFFECTIVE AGENT for increasing HDL

decreases VLDL & decreases LDL

Question 10

Statins

Answer 10

DOC: most effective at decreaseing LDL
PAE: liver damage, rhabdomylolysis

Question 11

Fibrates

Answer 11

Ind: most effective at decreasing triglycerides
PAE: decreases LDL, gemfibrizol blocks statins

Question 12

Zetia

Answer 12

Ind: decrease LDL, synergistic with statins

no AEs

Question 13

Quinidine

Answer 13

Ind: Acute & chronic supraventricular & ventricular arrhythmia
PAE: syncope, wide QT-I, cinchonism

Question 14

Lidocaine

Answer 14

DOC: acute ventricular arrhythmia

IV only

Question 15

Flecainamide

Answer 15

LAST DITCH ANTI-ARRYTHMIC

strongly pro-arrhythmic

Question 16

Amiodarone

Answer 16

DOC: CHRONIC ventricular arrhythmia (stable V tach)

Question 17

Verapamil

Answer 17

high heart effects w/low vessel effect

DO NOT MIX W/B-BLOCKERS

Question 18

Dilatezem

Answer 18

moderate heart & vessel effects-PSVT

Question 19

Adenosine

Answer 19

DOC: acute PVST, WPW
PAE: flushing

Question 20

Magensium

Answer 20

DOC: Torsades de Pointes

Question 21

Potassium

Answer 21

DOC: Digoxin toxicity

Question 22

Acetolamide

Answer 22

alkalinzation of urine

hyperuricemia

Question 23

Dorzolamide

Answer 23

closed angle gluacoma

Question 24

Brinzolamide

Answer 24

a carbonic anhydrase inhibitor with no mentioned DOC or PAE on this nice beginning dropbox chart

Question 25

Furosemide

Answer 25

Ind:MOST EFFECTIVE DIURETIC-CHF, edema, hypercalcemia, PE (w/morphine) PAEs: sulfonamide rxn, hypokalemic metabolic alkalosis, hypochloremia, hypocalcemia and hypomagnesemia, hyperuricemia

Question 26

Ethacrinic acid

Answer 26

NONSULFAMIDE loop | highest risk of OTOTOXICITY

Question 27

Thiazides

Answer 27

DOC: HTN; vasodilation due to PG synthesis PAEs: decreases insulin secretion, hyperglycemia, hypokalemia, hyperuricemia, hypomagnesemia, elevated serum lipids (except indapamide)

Question 28

Metolazone

Answer 28

sim to thiazides, used in LOW GFR pts (t, except metolazone]

Question 29

Indapamide

Answer 29

thiazide for ppl w/renal problems metabolized by liver, excreted in bile DOSEN"T INCREASE PLASMA LIPIDS

Question 30

Spironolactetone

Answer 30

[competitive inhibitor of aldosterone] Ind: HYPERALDOSTERONISM can use w/pts on thiazides instead of supplementing K caution w/ARB/ACE-I, hyperkalemia

Question 31

Amiloride

Answer 31

DOC: Li-induced diabetes insipidus | NO hyperuricemia, NOT AN ACID (Amiloride and Trimatrene are the only NONACIDS)

Question 32

Osmotics-mannitol

Answer 32

diuresis in AKD, decrease IOP, decrease ICP

Question 33

Desmopressin

Answer 33

central diabetes insipidus

Question 34

Conivaptan

Answer 34

Euvolemic/hypervolemic hyponatremia

Question 35

Lithium

Answer 35

Hyponatremia

Question 36

Demeclocycline

Answer 36

SIADH

Question 37

Digoxin

Answer 37

CHF/HTN decreases notmal tone via NaKATPase dec. HR, inc.CO, inc. contractility, increases BP incCO=inc baroreflex-dec. SNS=vasodilation PAE: bigemini, toxicity (GI early), blue vision, norrow therapeutic range Toxicity: inc Ca & dec. K

Question 38

Dopamine

Answer 38

end stage CHF-beta1 specific | decreased filling, increased oxygen consumption

Question 39

ACE-I (-prils) | ARBs (-sartans)

Answer 39

DOC: HTN & CHF (decreases mortality), increase diuretic effectiveness PAEs: ACE-I=cough hyperkalemia

Question 40

alpha blocker (-zosins)

Answer 40

BPH | PAE: first dose phenomenon

Question 41

Esmolol

Answer 41

short acting cardioselective beta blocker

Question 42

Clonidine

Answer 42

HTN | NOT for MONOTHERAPY

Question 43

Methyldopa

Answer 43

HTN in pregnancy | hemolytic anemia w/ (+) combs

Question 44

Labetolol

Answer 44

HTN emergencies w/o reflex tachycardia | hepatotoxic

Question 45

Hydralazine_isosorbide dinitrate

Answer 45

Best HTN in African americans | PAE: HIP drug

Question 46

Sodium nitroprusside

Answer 46

IV HTN emergencies | PAE: cyanide buildup & toxicity

Question 47

Minoxidil

Answer 47

chronic HTN | hair growth

Question 48

Fenoldopam

Answer 48

HTN emergencies via renal vasculature

Question 49

Dihydropyridines

Answer 49

CCDs-vasodilation w/less heart effect | DO NOT USE IN CHF

Question 50

Nefidiine

Answer 50

high vessel effect w/low heart effect | PAE: gingival hyperplasia

Question 51

Diltiazem

Answer 51

moderate heart & vessel effects-PSVT

Question 52

Verapamil

Answer 52

High heart effects w/low vessel effect | PAE: constipation

Question 53

Nitrates+CCBs

Answer 53

DOC Prinzmetals

Question 54

Nitrates

Answer 54

DOC Acute Angina | PAD: tolerance