Drug Dosages - Adult

Question 1

Adrenaline (ADX/ADM)

Repeat Adult Dosage

Answer 1

• ADX = 1mg every 3-5 mins - max 10 doses.

- ADM = 0.5mg every 5 mins - no max dose limit.

Question 2

Amiodarone (AMO)

Initial Adult Dosage

Answer 2

300mg IV - after 3rd shock.

Question 3

Amiodarone (AMO)

Repeat Adult Dosage

Answer 3

150mg IV - after 5th shock - no further repeat doses (max total 450mg)

Question 4

Aspirin (ASP)

Initial Adult Dose

Answer 4

300mg PO - no repeat doses.

Question 5

Atropine (ATR)

Initial Adult Dose

Answer 5

600mcg IV

Question 6

Atropine (ATR)

Repeat Adult Dose

Answer 6

600mcg IV - every 3-5 minutes - max total dose of 3mg.

Question 7

Benzylpenicillin (BPN)

Initial Adult Dose

Answer 7

• IV - 1.2g in 20ml water - no repeat doses.

- IM - 1.2g in 4ml water - no repeat doses.

Question 8

Chlorphenamine (CPH)

Initial Adult Dose

Answer 8

• IV - 10mg in 1ml - no repeat doses.

- PO - 4mg tablet - no repeat doses.

Question 9

Clopidogrel (CLO)

Initial Adult Dose

Answer 9

Dependent on pt care pathway (as per local protocol):

• Thrombolysis - 300mg (no repeat doses).
• PPCI - 600mg (no repeat doses).

Question 10

Diazepam (DZP)

Initial Adult Dose

Answer 10

IV - 10mg in 2ml

Rectal - 10mg or 20mg (single dose)

Question 11

Adrenaline (ADX/ADM)

Initial Adult Dosage

Answer 11

• Cardiac Arrest - 1mg IV (1:10,000 - ADX)

- Anaphylaxis & life-threatening asthma - 0.5mg IM (1:1000 - ADM)

Question 12

Diazepam (DZP)

Repeat Adult Dose

Answer 12

IV - 10mg after 5 mins (up to max total 20mg)

Question 13

Furosemide (FRM)

Initial Adult Dosage

Answer 13

40mg or 50mg (depending on presentation)
(Single dose only)

Administer slowly over 2 mins.

Question 14

Glucagon (GLU)

Initial Adult Dosage

Answer 14

1mg IM (Single dose only)

Question 15

Glucose 10% (GLX)

Initial Adult Dosage

Answer 15

10g (100ml) IV

Question 16

Glucose 10% (GLX)

Repeat Adult Dosage

Answer 16

10g (100ml) every 5 mins (max total dose of 30g (300ml))

Question 17

Glucose 40% Oral Gel (GLG)

Initial Adult Dosage

Answer 17

10g (in 25g tube) PO

Question 18

Glucose 40% Oral Gel (GLG)

Repeat Adult Dosage

Answer 18

10g (in 25g tube) PO every 5 mins (No Max Limit)

Question 19

Glyceryl Trinitrate (GTN)

Initial Adult Dosage

Answer 19

400-800mcg Sublingual spray

2mg, 3mg or 5mg Buccal tablet

Question 20

Glyceryl Trinitrate (GTN)

Repeat Adult Dosage

Answer 20

400-800mcg Sublingual spray
2mg, 3mg or 5mg Buccal tablet

Every 5-10 minutes (No Max limit)

Question 21

Heparin (HEP)

Initial Adult Dosage

Answer 21

When administered with Reteplase:
- 5000 units (1ml)

When administered with Tenecteplase:
- 4000 units (0.8ml) if 67kg

No repeat dose unless heparin infusion has not commenced within 45 mins of original bolus of Reteplase or Tenecteplase - in this case a further 1000 unit heparin bolus may be required.

Question 22

Hydrocortisone (HYC)

Initial Adult Dosage

Answer 22

Asthma & Adrenal Crisis - 100mg IV (No repeat doses)

Anaphylaxis - 200mg IV (No repeat doses)

Slow injection over min 2 minutes.

Can also be administered IM where IV access is impossible.

Question 23

Ibuprofen (IBP)

Initial Adult Dosage

Answer 23

400mg PO

Question 24

Ibuprofen (IBP)

Repeat Adult Dosage

Answer 24

400mg - every 8 hours

Max dose 1.2g per 24hrs.

Question 25

Ipratropium Bromide (IPR) Initial Adult Dosage

Answer 25

500mcg Nebulised with 6-8 L/min O2 | No repeat doses

Question 26

Metoclopramide (MTC) Initial Adult Dosage

Answer 26

10mg IV (No repeat dose)

Question 27

Misoprostol (MIS) Initial Adult Dosage

Answer 27

600mcg PO (3 x 200mcg tabs) - No repeat doses. 1mg PR (5 x 200mcg tabs) - No repeat doses.

Question 28

Morphine Sulphate (MOR) Initial Adult Dosage

Answer 28

IV - Diluted with NaCl (0.9%) to make 10mg in 10ml - should be administered slowly at rate of 2mg/min up to appropriate dose for age. IV - 10mg Oral - 20mg IM/Subcutaneous - 10mg (undiluted) Smaller doses can be administered at clinical discretion (please see full JRCALC for details)

Question 29

Morphine Sulphate (MOR) Repeat Adult Dosage

Answer 29

IV - 10mg at interval of 5 mins (Total max dose 20mg) PO - 20mg at interval of 60 mins (Total max dose 40mg) IM/Subcutaneous - 10mg at interval of 60 mins (Total max dose 20mg)

Question 30

Naloxone Hydrochloride (NLX) Initial Adult Dosage

Answer 30

400mcg IV/IM

Question 31

Naloxone Hydrochloride (NLX) Repeat Adult Dosage

Answer 31

400mcg IV/IM at interval of 3 mins (Total max dose 4400mcg) For IM doses vary administration site for repeat doses to avoid buildup of fluid intramuscularly.

Question 32

Ondansetron (ODT) Initial Adult Dosage

Answer 32

4 mg IV (slow injection over 2 mins)/IM

Question 33

Paracetamol (PAR) Initial Adult Dose

Answer 33

``` 1g PO (2 x 500mg tabs) 1g IV (100ml) ```

Question 34

Paracetamol (PAR) Repeat Adult Dose

Answer 34

1 gram every 4-6hrs (Max 4g in 24hrs)

Question 35

Reteplase (RPA) Initial Adult Dose

Answer 35

First dose - 10 units IV | Second dose after 30 mins - 10 units IV

Question 36

Salbutamol (SLB) Initial Adult Dose

Answer 36

5mg nebulised with 6-8 L/min O2

Question 37

Salbutamol (SLB) Repeat Adult Dose

Answer 37

5mg nebulised every 5 mins (No max limit)

Question 38

0.9% Sodium Chloride (SCP) Initial Adult Dose

Answer 38

Most conditions - 250ml except for: Sepsis - 1 litre Burns - 1 litre Limb crush injury - 2 litres

Question 39

0.9% Sodium Chloride (SCP) Repeat Adult Dose

Answer 39

Most conditions - 250ml with repeats PRN except for: Sepsis - 1 litre (repeat interval 30mins) Burns - 1 litre (no repeat doses) Limb crush injury - 2 litres (no repeat doses)

Question 40

Sodium Lactate Compound (SLC) Initial Adult Dosage

Answer 40

Most conditions - 250ml except for: Sepsis - 1 litre Burns - 1 litre Limb crush injury - 2 litres

Question 41

Sodium Lactate Compound (SLC) Repeat Adult Dosage

Answer 41

Most conditions - 250ml with repeats PRN except for: Sepsis - 1 litre (repeat interval 30mins) Burns - 1 litre (no repeat doses) Limb crush injury - 2 litres (no repeat doses)

Question 42

Syntometrine (SYN) Initial Adult Dosage

Answer 42

500mcg Ergometrine & 5 units oxytocin IM