Drug for eyes

Question 1

What bacteria’s cause conjunctivitis?

Answer 1

H.Flu & Streptococcus

Question 2

Aminoglycosides (tobramycin & gentamycin) cause

Answer 2

inflammation of eye, visual changes; usually rx by specialist

Question 3

stops bacteria from reproducing but does not eliminate exsisting

Answer 3

Bacitracin - inhibits incorporation of aa and nucleotides

Question 4

Bacitracin helps with

Answer 4

Gram + staph, strep, clostridia, corynebacteriaium and anaerobes
Gram - gonococci, meneingcocci & fusobacteria

Question 5

Erythromycin (EES)

Answer 5

inhibits bacterial protein synthesis

Question 6

Limited against gram -

Answer 6

EES

Question 7

ESS treats

Answer 7

staph aures
strep pneumonie, pyogènes, viridians
corynebacterium diptheride
chlamydia

Question 8

Sulfacetamide

Answer 8

inhibits bacterial dihydrofloate synthesis

Question 9

Active against strep, staph, E. coli, Klebsiella, pseudomans, gonorrhea & chlamydia

Answer 9

Sulfacetamide

Question 10

Gentamycin

Answer 10

UNK MOA
active against gram +&-
aminoglycoside

Question 11

tobramycin

Answer 11

UNK MOA
not active against chlamydia and gonorrhea
aminoglycoside

Question 12

covers 88% of gram +, 92% of gram - & 93% H.Flu

Answer 12

Azithromycin

Question 13

inhibits DNA gyrase

Answer 13

Fluoroquinolones

Question 14

polymyxin B & trimethoprim
covers gram + & -
active against strep pneuo & pyogenes

Answer 14

Polytrim

Question 15

binds to cell wall and increases permeability

Answer 15

Polymycin

Question 16

inhibits bacterial dihydrofolate reductase

Answer 16

trimethoprim

Question 17

active against + & -
polymyxin B & bacitracin

Answer 17

polysporin

Question 18

anti virals rx by

Answer 18

ophthalmologist

Question 19

Gancyclovir

Answer 19

antiviral for eye agent

Question 20

Vidarabine

Answer 20

antiviral for eye agent

Question 21

Trifluridine

Answer 21

antiviral for eye agent

Question 22

Zirgan - antiviral for eye agent

Answer 22

inhibits replication of HSV

Question 23

Vira - A - antiviral for eye agent

Answer 23

active against HSV 1&2, VZV, CMV, Vaccinia, HepB

Question 24

Viroptic

Answer 24

HSV 1 &2, Adenovirus, Vaccinia

Question 25

pt is post trauma/ sx

Answer 25

no ointment, decrease healing of cornea

Question 26

paraminobenzocis acid containing pus

Answer 26

no sulfacetamides, it inactivates

Question 27

-floxcin, cipro, gentamycin, polymyxin B & sulfacetamides

Answer 27

category C - no pregnant women use

Question 28

safe for children

Answer 28

Tobramycin and EES

Question 29

Moxifloxacin

Answer 29

expensive; use for 4M olds +

Question 30

not okay for use of 2M or less

Answer 30

sulfacemides & polymyxin B

Question 31

ADR

Answer 31

superinfection with prolonged use/ repetitive use

Question 32

what abx causes transient blurred vision

Answer 32

bacitracin

Question 33

ADR of local ocular toxicity and hypersensitivity

Answer 33

amnioglycoside

Question 34

ADR of white crystal precipitate in superficial cornea (17% w cipro), lid crusting, crystal scales, & sense of foreign body in eye; dysgesusia (funny taste)

Answer 34

Fluoroquinolones

Question 35

ADR: photophobia, tearing, nausea, decrease vision, corneal staining

Answer 35

Fluoroquinolones

Question 36

ADR - antivirals

Answer 36

burning, irritation w application

Question 37

ADR of punctate keratitis (opacities in eye), conjunctival hyperemia (eye redness)

Answer 37

Gancyclovir

Question 38

ADR of photophobia, itching, erythema, ocular pain, tears, punctate keratitis with UV light (use sunglasses)

Answer 38

Vidarabine

Question 39

ADR IOP

Answer 39

Trifluridine

Question 40

which meds have no drug/drug interactions?

Answer 40

bacitracin gentamicin tobramycin polymyxin B azithromycin EES

Question 41

incompatible w silver preparation (infants)

Answer 41

sulfacetamide

Question 42

antagonist to sulfacetamides

Answer 42

-caine meds

Question 43

increase in theophylline levels & INR

Answer 43

fluoroquinolones

Question 44

seen in preschoolers

Answer 44

bacterial conjunctivitis

Question 45

seen in neonates <1M caused by chlamydia

Answer 45

ophthalmia neonatrum

Question 46

viral & bacterial conjunctivitis

Answer 46

adults

Question 47

GC most common

Answer 47

ophthalmia neonatrum

Question 47

seen in neonates and promiscuous adults

Answer 47

chlamydia

Question 48

IM ceftriaxone 1 dose don't use with high billi level

Answer 48

ophthalmia neonatrum

Question 49

cefoxaxmine 50mg/kg/day BID for 7 days

Answer 49

ophthalmia neonatrum with high bili

Question 50

EES ointment 1 hrs post birth

Answer 50

prevention of ophthalmia neonatrum

Question 51

systematic EES or azithromycin

Answer 51

chlamydia

Question 52

not prevented with EES at birth

Answer 52

chlamydia

Question 53

mucopurulent at discharge and during the first weeks of birth

Answer 53

check for chlamydia

Question 54

most common in 7yrs +

Answer 54

bacterial conjuntivitis

Question 55

commonly seen in warm climates

Answer 55

strep causing bacterial conjuntivitis

Question 56

non-typable h.flu

Answer 56

bacterial conjuntivitis in warm climates

Question 57

staph auerus and pseudomonas bacterial conjunctivitis

Answer 57

seen in >70yrs

Question 58

treatment for bacterial conjuntivitis

Answer 58

EES ointment polytrim or polysporin sulfacetamide - doesn't cover h.flu and stings

Question 59

conjunctivitis w otitis syndrome

Answer 59

eye and OM 6 yrs of age or less treat w PO Augmentin 80-90mg/kg

Question 60

GC conjuntivitis

Answer 60

purulent bacterial respond to topical tx do gram stain & culture for NB w hyperpulurent and promiscuous mother

Question 61

rocephin IM 1g x1 ns irrigations

Answer 61

GC conjuntivitis

Question 62

inflammation of lash follicles

Answer 62

blepharitis

Question 63

treatment for blepharitis

Answer 63

warm compresses scrub lashes w gentle, tear free shampoo EES ointment .25" ribbon to eye BIN until revolved then for another week ointment is preferred Zithromax solution 1% BID for 1M no contacts discard eye make up

Question 64

Hordeolum (STYE)

Answer 64

infection of sebaceous gland caused by staph aureus

Question 65

stye tx

Answer 65

warm compress sulfacetamide 10% or polytrim drops or EES ointment QID until resolved + 3 days

Question 66

viral conjunctivitis is cause by

Answer 66

adenovirus, HSV or VZV

Question 67

adenovirus causing conjunctivitis tx

Answer 67

sulfacetamide 10% (solution or ointment) tobramycin prevents superinfection

Question 68

HSV causing conjunctivitis

Answer 68

keratitis complication seen specialist

Question 69

gancyclovir, trifluridine or vidarabine

Answer 69

tx viral conjunctivitis

Question 70

poor coverage for H.flu causing infection

Answer 70

sulfacetamide

Question 71

good coverage H.Flu

Answer 71

polytrim

Question 72

infant DOC

Answer 72

EEC

Question 73

10x the cost of EES

Answer 73

Zithromax and fluoroquinolone