Drug Interactions Part A Flashcards Preview

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Flashcards in Drug Interactions Part A Deck (15)
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1
Q

Use of multiple drugs

A

Polypharmacy

2
Q

When drugs work against each other.

A

Antagonism

3
Q

When drugs work with each other.

A

Synergism

4
Q

Types of synergism

A

1) Additive

2) Potentiation

5
Q

These decrease the absorption of Tetracyclines and other drugs.

A

Antacids and Metamucil

6
Q

Acidic things like grapefruit, mango, papaya, and guava increase or decrease absorption of drugs?

A

Increase

7
Q

Hydrolyzes Penicillin

A

Acids in fruit juice

8
Q

Foods that cause drug interactions.

A

1) Grapefruit juice
2) Iron
3) Calcium
4) Antacids
5) Metamucil

9
Q

Barbiturates affect which organ and what does it cause in that organ?

A

Liver

Increase the enzyme activity of hepatocytes.

10
Q

Drugs that are metabolized faster when taking barbiturates.

A
  • Anticoagulants
  • Phenytoin
  • Tricyclics
  • Corticosteroids
  • Monoamine oxidase inhibitors.
11
Q

How do you increase the onset of a drug?

A

Put it in the LIQUID form.

12
Q

Drugs that have additive effects.

A

1) Sedatives and Hypnotics
2) Tranquilizers
3) Alcohol
4) Calcium channel blockers and Cyclosporin (both cause gingival enlargement)
5) Antihistamines
6) Narcotic analgesics
7) Tricyclic antidepressants

13
Q

T/F:

Don’t give bacteriostatic drugs with bactericidal drugs, because they work in opposite ways.

A

True

14
Q

Example of antibiotic antagonism.

A

Pencillin and Tetracycline

15
Q

Do antihistamines and epi antagonize or synergize?

A

Antagonize bc antihistamine is a vasodilator, and epi is a vasoconstrictor.