Drug List 1 Flashcards

Question

Bupropion (Wellbutrin) Precautions?

Answer 1

seizures, eating disorder, stopped using alcohol, seizure meds, or sedatives Do not use for 14 days after MAO inhibitors

Answer 2

azapirone (anxiolytic)

Answer 3

anxiety PTSD

Answer 4

stimulatrs 5-hydroxytryptamine (serotonin) receptors in brain Serotonin receptor agonist

Answer 5

headache, dizziness, drowsiness, insomnia, nausea, nervous or excited

Answer 6

MAO inhibitor in past 14 days

Answer 7

First generation Antiepileptic (anticonvulsant)

Answer 8

seizures can treat bipolar

Answer 9

decrease neuronal excitability by decreasing sodium entry into neurons decrease sodium entry into neurons slow down firing rate of neurons

Answer 10

Dizziness, drowsiness, water retention, cardia arrhythmias, Congestive heart failure

Answer 11

dont take if you have history of bone marrow suppression taken MAO in past 14 days may cause severe or life-threatening skin rash (especially in Asian ancestry) tell doctor right away if you become pregnant

Answer 12

Traditional antipsychotic

Answer 13

Schizophrenia manic-depression

Answer 14

strong dopamine receptor antagonists (blockers) strong affinity for dopamine type 2 (D2) postsynaptic receptors in limbic system

Answer 15

increased risk for movement disorders and motor side effects with long-term use sedation, anticholinergic potential tardive dyskinesia (extrapyramidal) Neuroleptic Malignant Syndrome (potential for high dose)

Answer 16

dont use with older adults with dementia dont take with large amounts of alcohol or sleeping meds

Answer 17

Benzodiazepine

Answer 18

panic disorder (anxiety) can also treat seizure

Answer 19

effect GABA receptors also act on GABA at spinal cord level which may lead to relaxation of skeletal muscles (GABA is an inhibitory neurotransmitter)

Answer 20

sedation feeling tired or depressed, drowsiness, dizziness, memory problems, problems with walking or coordination

Answer 21

can cause addiction, overdose, or death do not stop med suddenly DO NOT drink alcohol avoid driving or hazardous activity falls, accidents, or severe injuries

Answer 22

Atypical Antipsychotic

Answer 23

schizophrenia

Answer 24

Weak dopamine D2 receptor antagonists Strong serotonin receptor antagonists

Answer 25

movement disorders at high levels but less than typical antipsychotic meds increase risk of seizure at high doses tardive dysnkinesia metabolic: weight gain orthostatic hypotension sedation anticholinergic effects

Answer 26

AVOID alcohol avoid tea, coffee, cola, energy drinks, or other caffeine no driving can cause falls, accidents, or severe injuries avoid getting up too fast may increase risk of death with dementia

Answer 27

Benzodiazepine

Answer 28

anxiety can be alcohol withdrawl

Answer 29

bind and increase inhibitory effects of GABA causing sleepiness and calmness

Answer 30

drowsiness, tired, muscle weakness, balance or muscle movement difficulty

Answer 31

Can cause addiction, overdose, or death fatal side effects with use of opioid meds, alcohol, or other sleepy drugs, drugs that slow breathing do not use with: myasthenia gravis sleep apnea liver disease Do not use if pregnant

Answer 32

Selective Serotonin Reuptake Inhibitor (SSRI) antidepressant

Answer 33

depression (major-depressive) OCD, bulimia nervosa, panic

Answer 34

inhibit reuptake of serotonin is selective for serotonin (5-hydrozytryptamine)

Answer 35

nausea, vomiting, diarrhea or constipation may cause serotonin syndrome (potentially fatal) due to excessive serotonin accumulation causes sweating, agitation, restlessness, shivering, tachycardia, motor abnormalities reversible if drug is stopped

Answer 36

do not use with MAO inhib or 14 days after use caution when operating machinery impairs judgement, thinking, or motor skills

Answer 37

Benzodiazepine

Answer 38

increase inhib effect of GABA on CNS, leads to decreased excitation and enhances relation and sleepiness

Answer 39

drowsiness, dizziness, and lightheaded loss of coordination falling or staggering

Answer 40

Can cause addiction, overdose, or death do not use if pregnant, or breastfeeding have to be older than 18

Answer 41

Traditional antipsychotic

Answer 42

schizophrenia

Answer 43

strong affinity for dopamine type 2 (D2) postsynaptic receptors in limbic system strong dopamine receptor antagonists High potency

Answer 44

increased risk of movement disorders and motor side effects drowsiness, headache, dizziness, uncontrolled muscle movements, feeling restless or anxious, insomnia, breast enlargement, irregular menstrual periods

Answer 45

not approved for older adults with dementia, parkinson's disease, CNS conditions

Answer 46

Dopaminergic antiparkinson

Answer 47

Parkinson's

Answer 48

Carbidopa prevents breakdown of levodopa i the periphery, which allows more levodopa to reach the brain

Answer 49

jerky twisting muscle movements (dyskinesia), headache, dizziness, low BP, sleep problems, strange dreams, muscle contractions, arrhythmias, behavioral changes, freezing of gait,

Answer 50

risk of falls from freezing of gait Do not take if used MAO inhib in past 14 days do not use if you have narrow-angle glaucoma

Answer 51

antimanic agent

Answer 52

Bipolar disorder

Answer 53

may influence neuronal excitability by competing with other cations like calcium, sodium, and potassium

Answer 54

lithium toxicity, ataxia, tremor, rigidity, myoclonus (sudden involuntary twitching or jerking)

Answer 55

watch for lithium toxicity do not use if pregnant (talk to doc first) do not breast-feed Avoid becoming overheated or dehydrated during exercise and in hot weather be cautious with driving

Answer 56

Benzodiazepine

Answer 57

insomnia caused by anxiety can also treat nausea from cancer treatments and aid in alcohol withdrawal

Answer 58

increase inhib effect of GABA on CNS, leads to decreased excitation and enhances relation and sleepiness

Answer 59

sedation dizziness, weakness, feeling unsteady

Answer 60

can cause addiction, overdose, or death do not use if pregnant/breastfeeding do not use if you have narrow-angle glaucoma, severe respiratory insufficiency, myasthenia gravis, or allergic to benzos

Answer 61

Second-generation Antiepileptic (anticonvulsant)

Answer 62

seizures can treat nerve pain from shingles, and restless leg syndrome

Answer 63

decrease release of glutamate from presynaptic neurons glutamate is excitatory nt decrease leads to decrease in neuronal activity

Answer 64

Sedation, fatigue, dizziness, ataxia

Answer 65

avoid driving fall risk avoid taking antacid within 2 hours before dont drink alcohol

Answer 66

Tricyclic antidepressants

Answer 67

depression

Answer 68

block reuptake of all 3 amines: serotonin, norepinephrine, dopamine

Answer 69

Sedation, anticholinergic, cardiac arrhythmias, orthostatic hypotension, seizures, high potential for lethal overdose

Answer 70

less selective so tend to have more interactions with other drugs and are more harmful during overdose

Answer 71

Selective Serotonin Reuptake Inhibitors (SSRI)

Answer 72

depression

Answer 73

inhibit reuptake of serotonin is selective for serotonin (5-hydrozytryptamine)

Answer 74

nausea, vomiting, diarrhea or constipation are most common serotonin syndrome (sweating, agitation, restlessness, shivering, tachycardia, tremors, clonus, rigidity)

Answer 75

dont take with pimozide or thioridazine dont use within 14 days of MAO DO NOT stop this medication without doctor's advice don't breastfeed while using med

Answer 76

Monoamine Oxidase Inhibitor (MAOI)

Answer 77

atypical depression in adults when other meds have not been effective can treat bipolar depression

Answer 78

Inhibits MAO which is an enzyme the breaks down neurotransmitters, thus leaving them in the synaptic cleft longer

Answer 79

CNS excitation restlessness, irritability, agitation, sleep loss anticholinergic effects hypertensive crisis if taken with fermented foods like tyramine

Answer 80

many drugs, foods, and beverages that can cause dangerously high BP don't use if: pheochromocytoma, congestive heart failure, severe kidney disease, history of liver problems or abnormal liver function

Answer 81

barbiturate

Answer 82

prevent seizures, short term sedative

Answer 83

bind to other sites on GABA A and enhance inhib of GABA

Answer 84

may cause a severe allergic reaction weak or shallow breathing unusual pain in body red blood cell disorder severe skin reaction hangover effect, drunk feeling, restless, dizziness or spinning sensation, drowsy

Answer 85

dont use if have liver disease, severe asthma, COPD, family history of porphyria, history of addiction to drugs VERY ADDICTIVE and strong chance of abuse

Answer 86

First-generation Antiepileptic aka Anticonvulsant (barbiturate)

Answer 87

increase activity of CNS inhibitory neurons at synapses that use GABA

Answer 88

sedation is primary hyperactivity in kids nystagmus (uncontrollable eye movements) ataxia (degenerative disease of neuro)

Answer 89

overdose can be lethal (small TI) Do not stop taking unless discussion with doctor don't take if you have liver problems, allergies to similar meds, currently taking Rescriptor

Answer 90

atypical antipsychotic

Answer 91

schizophrenia and bipolar disorder can treat symptoms of irritability in autistic kids

Answer 92

Strong sertonin receptor antagonists blocks serotonin receptors in the limbic system weak block dopamine (D2)

Answer 93

increased risk of abnormal movement patterns Extrapyramidal side effects (tardive dyskinesia) Neuroleptic malignant syndrome sedation orthostatic hypotension Anticholinergic effects

Answer 94

not approved for people with dementia avoid getting too cold, hot, or dehydrated may impair thinking or reactions

Answer 95

Barbiturate (sedative)

Answer 96

Binds to other sites on GABA A and enhance inhib of GABA

Answer 97

drowsiness, hangover effect, headache, dizziness, memory problems, dry mouth, upset stomach, restless or excited

Answer 98

do not use if you have severe liver disease, severe breathing problems, poryphyria makes birth control less effective can cause problems with pregnancy and breastfeeding

Answer 99

benzodiazepine

Answer 100

increase inhibitory effects of GABA A on CNS

Answer 101

can slow breathing drowsiness, loss of coordination (fall risk), dizziness, light-headed anterograde amnesia

Answer 102

CAN Cause addiction, overdose or death can cause issues if recently taken opioid meds or alcohol Do not stop meds do not breastfeed within 28 weeks of use if pregnant can fuck up your baby

Answer 103

First generation Antiepileptic (anticonvulsant) barbiturates

Answer 104

seizures bipolar disorder and prevent migraines

Answer 105

limit sodium entry into rapidly firing neurons decrease firing rate of neurons

Answer 106

GI distress temporary hair loss impaired platelet function tremors, problems walking blurred vision changes in appetite or weight gain

Answer 107

do not use with liver disease avoid drinking alcohol and driving

Answer 108

Serotonin-norepinephrine reuptake inhibitor (SNRI)

Answer 109

depression and generalized anxiety

Answer 110

blocks reuptake of serotonin and norepinephrine allowed to remain in synaptic cleft for longer period of time

Answer 111

nausea, vomiting, diarrhea or constipation serotonin syndrome feel anxious

Answer 112

dont take with narrow-angle glaucoma if used an MAO recently dont drink alcohol ask to use an NSAID

Answer 113

Nonbenzodiazepine sedative and hypnotic also an anxiolytic

Answer 114

bind to GABA A in brain

Answer 115

hangover effect, light-headed, problems with coordination, numbness, tingling, prickly skin

Answer 116

anterograde amnesia activities in sleep with no memory can result in serious injury or death not approved for <18 yr-old dont take in pregnant or breastfeeding falls are common in elderly Misuse can cause addiction, overdose, or death dont drink alcohol

Answer 117

Nonbenzodiazepine sedative and hypnotic also an anxiolytic

Answer 118

bind to GABA A in brain

Answer 119

Complex motor behaviors (sleep walking, sleep driving, sleep eating) very common daytime drowsiness, dizziness, light headed headache diarrhea

Answer 120

Never use larger amounts or for longer than prescribed do not take if you have consumed alcohol during the day or just before bed increase in risk of falls dont breastfeed baby within 23 hours of taking med

Drug List 1 Flashcards

(150 cards)