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4BBY1040 > Drug List > Flashcards

Drug List Flashcards

1
Q

Hemicholinium

A

Stops uptake of choline at neuromuscular junction

Prevent synthesis of acetylcholine

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2
Q

AH5183 (Vesamicol)

A

Stops storage mechanism of acetylcholine at neuromuscular junction

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3
Q

Botulinum toxin (botox)

A

Stops acetylcholine from releasing at neuromuscular junction

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4
Q

Mg2+

A

Block Ca2+ channel

Stops acetylcholine from releasing at neuromuscular junction

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5
Q

Suxamethonium

A

Produce prolonged depolarisation
2 ACh binded together
Depolarising muscle relaxants, used for short period muscle relaxation

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6
Q

Neostigmine

A

Anticholinesterase
Treat myasthenic gravis
Can be used to reverse muscle relaxant effect

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7
Q

Edrophonium

A

Anticholinesterase

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8
Q

Tubocurarine

A

Reversible competitive antagonists of NAChR

Act as muscle relaxants

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9
Q

Vecuronium

A

Reversible competitive antagonists of NAChR

Act as muscle relaxants

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10
Q

Atracurium

A

Reversible competitive antagonists of NAChR

Act as muscle relaxants

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11
Q

Pancuronium

A

Reversible competitive antagonists of NAChR

Act as muscle relaxants

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12
Q

Pilocarpine

A

Muscarinic agonists

Treat glaucoma

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13
Q

Bethanechol

A

Muscarinic agonists
Stimulates gut motility
Assists bladder emptying

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14
Q

Atropine

A

Non-selective muscarinic antagonists
Block secretions, mild tachycardia
Dilates pupil

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15
Q

Hyoscine

A

Muscarinic antagonists
Block mucous secretions
Anti-motion sickness drug

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16
Q

Ipratropium

A 
Muscarinic antagonists
Treat asthma (Bronchodilator)
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17
Q

Tolterodine

A

Muscarinic antagonists

Treat urinary incontinence

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18
Q

Hexamethonium

A

Nicotinic antagonists

Anti-hypertensive drug, reduce blood pressure

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19
Q

Trimetaphan

A

Nicotinic antagonists
Lower blood pressure, reduce bleeding
Rarely used in surgery

20
Q

Dyflos

A

Anticholinesterase

Irreversible

21
Q

Parathion

A

Anticholinesterase
Irreversible
Phosphorylate the esteratic site

22
Q

Ecothiopate

A

Anticholinesterase
Irreversible
Phosphorylate the esteratic site
Treat glaucoma

23
Q

Pralidoxime

A

Reative phosphorylated cholinesterase (BChE)

24
Q

a-methyl-p-tyrosine

A

Block tyrosine hydroxylase
Prevent Tyrosine –> L-DOPA
Used in treatment of tumours of adrenal medulla

25
Q

Carbidopa

A

Block Dopa Decarboxylase (DDC)

Used to treat Parkinson’s disease (given with L-Dopa)

26
Q

Reserpine

A

Block vesicular monoamine transporter (VMAT)
Prevent storage of noradrenaline
Used as an anti-hypertensive drug (lower blood pressure)

27
Q

Guanthidine

A

Block release of catecholamines (NA/Adrenaline)

28
Q

Imipramine

A

Block Uptake 1
Enhance sympathetic neurotransmission
Tricycle antidepressants

29
Q

Amitriptyline

A

Block Uptake 1
Enhance sympathetic neurotransmission
Tricycle antidepressants

30
Q

Monoamine oxidase inhibitor

A

Prevent breakdown of NA / adrenaline

Must alter their diet, prevent high level of tyramine

31
Q

Amphetamine

A

Displaces NA from storage sites
Enter to presynaptic knob by Uptake 1 mechanism
Increase NA release

32
Q

Tyramine

A

Taken up into nerve terminals by NET (Uptake 1)
Causes release of cathecolamines

Effects are increased by MAO inhibitors

33
Q

Cocaine

A

Block reuptake transport into nerve terminals (Uptake 2)

34
Q

Imipramine

A

Block reuptake of NA at nerve endings

Anti-depressive drug

35
Q

Phenylephrine

A

alpha-1 adrenoceptor agonists

Treat hypotension and nasal congestion

36
Q

Tizanidine

A

alpha-2 adrenoceptor agonists

Acts as muscle relaxant

37
Q

Isoprenaline

A

beta-selective adrenoceptor agonists

Used for acute heart block treatment

38
Q

Salbutamol

A

beta-2 adrenoceptor agonists

Treat asthma

39
Q

Dobutamine

A

beta-1 adrenoceptor agonists

Increase cardiac output

40
Q

Phenoxybenzamine

A

Non-selective alpha-adrenoceptor blocker
irreversible
Used in treatment of phaechromocytoma (adrenal gland tissue tumour)

41
Q

Phentolamine

A

Non-selective alpha-adrenoceptor blocker
Reversible
Used in treatment of phaechromocytoma (adrenal gland tissue tumour)

42
Q

Prazosin

A

alpha-1 block

Used as antihypertensive

43
Q

Labetalol

A

non-selective beta-adrenoceptor blocker
Used to treat stable congestive heart failure
Reduce arterial blood pressure

44
Q

Carveldilol

A

non-selective beta-adrenoceptor blocker
Used to treat stable congestive heart failure
Reduce arterial blood pressure

45
Q

Propanolol

A

Selective beta blocker

Treat disturbances of cardiac rhythm, myocardial infarction and angina

46
Q

Metoprolol

A

Selective beta-1 blocker

Treat disturbances of cardiac rhythm, myocardial infarction and angina

4BBY1040 (1 decks)

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