Drug MOA/Indications Combo Flashcards

(25 cards)

1
Q

Carbamazepine

A

Enhanced Fast Inactivation

Broad Spectrum

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2
Q

Oxcarbazepine

A

Enhanced Fast Inactivation

Simple & Complex

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3
Q

Eslicarbazepine

A

Enhanced Fast Inactivation

Simple & Complex

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4
Q

Lacosamide

A

Enhanced Fast Inactivation, Enhanced Slow Inactivation

Simple & Complex

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5
Q

Lamotrigine

A

Enhanced Fast Inactivation

Simple & Complex

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6
Q

Phenytoin

A

Enhanced Fast Inactivation

Broad Spectrum, Status Epilepticus

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7
Q

Rufinamide

A

Enhanced Fast Inactivation

Lennox-Gastraut

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8
Q

Topiramate

A

Enhanced Fast Inactivation, Post-synaptic, Glutamate (AMPA)

Broad Spectrum, Lennox-Gastaut

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9
Q

Valproic Acid

A

Enhanced Fast Inactivation, GABA-T Inhibition, Ca²+ Type-T Channel

Absence, Broad Spectrum, Status Epilepticus

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10
Q

Zonisamide

A

Enhanced Fast Inactivation, Ca²+ Type-T Channel

Simple & Complex

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11
Q

Tiagabine

A

GAT-1 Inhibition

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12
Q

Vigabatrin

A

GABA-T Inhibition

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13
Q

Phenobarbital

A

Post-synaptic

Broad Spectrum, Status Epilepticus

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14
Q

Primidone

A

Post-synaptic

Simple & Complex

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15
Q

Clonazepam

A

Post-synaptic

Absence, Myoclonic, Lennox-Gastaut

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16
Q

Clorazepate

A

Post-synaptic

Simple & Complex

17
Q

Lorazepam

A

Post-synaptic

Status Epilepticus

18
Q

Diazepam

A

Post-synaptic

Status Epilepticus

19
Q

Ethosuximide

A

Ca2+ type-T channel

Absence

20
Q

Perampanel

A

Glutamate (AMPA)

21
Q

Felbamate

A

Glycine (NMDA)

Simple & Complex, Lennox-Gastaut

22
Q

Levetiracetam

A

Simple Vesicle Protein (SV2A)

Status Epilepticus

23
Q

Brivaracetam

A

Simple Vesicle Protein (SV2A)

24
Q

Gabapentin

A

Alpha 2 δ Channel

25
Pregabalin
Alpha 2 δ Channel