Drug Monitoring

Question 1

What are the monitoring parameters for statins?

Answer 1

LFT
At:
* Baseline
* 3 months
* 12 months

Question 2

What are the monitoring parameters for ACE inhibitors?

Answer 2

U&E
* Prior to treatment
* After increasing dose
* At least annually

Question 3

What are the monitoring parameters for amiodarone?

Answer 3

TFT
LFT

• TFT, LFT, U&E, CXR prior to treatment
• TFT and LFT every 6 months

Question 4

What are the monitoring parameters for DOACs?

Answer 4

Renal funtcion (creatinine clearance)

Added this on myself

Question 5

What are the monitoring parameters for mthotrexate?

Answer 5

FBC
LFT
U&E

The Committee on Safety of Medicines recommend ‘FBC and renal and LFTs before starting treatment and repeated weekly until therapy stabilised, thereafter patients should be monitored every 2-3 months’

Question 6

What are the monitoring paramters for azathioprine?

Answer 6

FBC
LFT

• FBC, LFT before treatment
• FBC weekly for the first 4 weeks
• FBC, LFT every 3 months

Question 7

What are the monitoring parameters for lithium?

Answer 7

Lithium
TFT
U&E

• Prior to treatment → TFT, U&E
• Lithium levels weekly until stabilised → then every 3 months
• TFT, U&E every 6 months

Question 8

What are the monitoring parameters for sodium valproate?

Answer 8

LFT

Before treatment → LFT, FBC
LFT ‘periodically’ during first 6 months

Question 9

What are the monitoring parameters for glitazones?

Answer 9

LFT

Before treatment → LFT
LFT ‘regularly’ during treatment

Question 10

The tables below show the monitoring requirements of common drugs. It should be noted these are basic guidelines and do not relate to monitoring effectiveness of treatment (e.g. Checking lipids for patients taking a statin)

Answer 10

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