Drug Names: CV Flashcards
(107 cards)
1
Q
Propanolol
A
Non-Selective Beta Blocker (Class II Antiarrhythmic)
2
Q
Carveidilol
A
Non-selective Beta Blocker (Class II Antiarrhythmic). Also blocks Alpha 1 (relaxes smooth muscle…)
3
Q
Sotalol
A
Non-selective BB (Class II anti-a)
But also acts as a Class III anti-a as it inhibits the influx of K+ during the Phase 3 repolarisation. Thus increases refractory perior in all cardiac tissues
4
Q
Metoprolol
A
Cardio-selective BB (Class II anti-a)
5
Q
Atenolol
A
Cardio-selective BB (Class II anti-a)
6
Q
Bisoprolol
A
Cardio-selective BB (Class II anti-a)
7
Q
Nebivolol
A
Cardio-selective BB (Class II anti-a)
8
Q
Prazosin
A
a1 Antagonist (Post-synaptic terminal) (relax smooth muscle)
9
Q
Methyldopa
A
A2 Agonist (Pre-synaptic terminal) (relax smooth muscle)
10
Q
Clonidine
A
A2 Agonist (pre-synaptic terminal) (relax smooth muscle)
11
Q
Monoxidine
A
A2 Agonist (Pre-synaptic terminal) (relax smooth muscle)
12
Q
Nifedipine
A
Dihydropyridine CCB (Class IV anti-a)
13
Q
Felodipine
A
Dihydropyridine CCB (Class IV anti-a)
14
Q
Amlodopine
A
Dihydropyridine CCB (Class IV anti-a)
15
Q
Diltiazem
A
Benzothiazepine CCH (Class IV anti-a)
16
Q
Verapamil
A
Phenylalkylamina CCH (Class IV anti-a)
17
Q
Glyceryl Trinitrate
A
Nitrate
18
Q
Isosorbide mononitrate
A
Nitrate longer acting
19
Q
Isosorbide Dinatrate
A
Nitrate longer acting
20
Q
Nicorandil
A
Nitrate
21
Q
Perhexiline
A
Nitrate
22
Q
Enalapril
A
ACEI
23
Q
Captopril
A
ACEI
24
Q
Fosinopril
A
ACEI
25
Lisinopril
ACEI
26
Candesartan
ARBs
27
Irbesartan
ARBs
28
Losartan
ARBs
29
Mannitol
Osmotic Diuretics
30
Hydrochlorothiazide
Thiazide
31
Chlorthalidone
Thiazide
32
Bendofluazide
Thiazide
33
Indapamide
Thiazide
34
Frusemide
Loop Diuretic
35
Ethecrynic Acid
Loop Diuretic
36
Bumetanide
Loop Diuretic
37
Piretanide
Loop Diuretic
38
Spironolactone
K+ Sparing Diuretic
39
Amiloride
K+ Sparing Diuretic
40
Triamterene
K+ Sparing Diuretic
41
Allopurinol
Used for gout, which can be a side effect of diuretics
42
Quinidine
Class 1a Anti-a
43
Lignocaine
Class 1b Anti-a
44
Mexiletine
Class 1b Anti-a
45
Flecainide
Class 1c Anti-a
46
Amiodarone
Class III Anti-a. Also has actions similar to Class IV(CCB), Class II (BB) and Class I(inhibits Na+ influx during phase 0). **Amiodarone pulmonary fibrosis and thyroid problems**
47
Sotalol
Non-selective BB AND Class III Anti-a
48
Digoxin
Class V Anti-a
49
Atropine
Class V Anti-a AND Endogenous neurotransmitter used in shock
50
Adenosine
Class V
51
Adrenaline
Class V
52
Isoprenaline
Class V
53
Noradrenaline/Adrenaline
ENdogenous Neurotransmitters. Used in Shock
54
Atropine
Endogenous Neurotransmitters. Used in Shock. AND Class V
55
Dopamine
Endogenous Neurotransmitters. Used in Shock.
56
Vasopressin
Endogenous Neurotransmitter. Used in Shock
57
Dobutamine
Sympathomimmetic - used in shock
58
Saline
Crystalloid Fluid replacement
59
Albumex
Colloid Fluid Replacement
60
Haematcel
Colloid Fluid Replacement
61
Activated Protein C
Anticoagulation treatment in shock
62
Gemfibrozil
TG-lowering drug
63
Nicotinic Acid
TG-lowering drug
64
Atorvastatin
LDL-lowering statin
65
Simvastatin
LDL-lowering statin
66
Pravastatin
LDL-lowering statin
67
Fluvastatin
LDL-lowering statin
68
Cholestyramine
Cholesterol Absorption Inhibitor
69
Ezetimibe
Cholesterol Absorption Inhibitor
70
Torcetrapid
HDL increasing drug?
71
Low dose aspirin
Anti-platelet
72
Clopidogrel
Anti-platelet
73
Abciximab
Anti-platelet
74
Streptokinase
Fibrinolytic/thrombolytic drug
75
TPA, rTPA: Alteplase, Reteplase, Tenecteplase
Fibrinolytic/thrombolytic drugs
76
Heparin
Anti coagulant
77
LMWH
Anti-coagulant
78
Warfarin
Anti coagulant
79
Rivaroxaban
Anti coagulant
80
Dabigatran
Anti coagulant
81
Apixaban
Anti coagulant
82
Vitamin K
Pro-coagulant
83
codeine, pholcodeine, oxycodone, dihydocodeine, dextromethorphan
Anti-tussives for dry cough
84
Guaifenesin, ammonium salts, senega, liquorice and sodium citrate
Anti-tussives: Expectorants
85
Linctus
Anti-tussive: productive cough, demulcents
86
Bromhexine, Acetylcysteine
Anti-tussives: Mucolytics
87
Codeine, Paracetamol
Analgesics
88
Prednisolone
Oral Glucocorticoid (anti-inflammatory, respiratory)
89
Becolmethasone
Preventer: Inhaled glucocorticoids
90
Budesonide
Preventer: Inhaled glucocorticoids
91
Fluticasone
Preventer: Inhaled Glucocorticoids
92
Salbutamol
Reliever: SABA (bronchidilator) (ventolin) (bronchodilation + decresed mucous production)
93
Terbutaline
Reliever: SABA (bronchidilator) (Bricanyl) (bronchodilation + decreased mucous production)
94
Salmeterol
Preventer: LABA (severent) (bronchodilation + decreased mucous production)
95
Eformeterol
Preventer: LABA (Oxis) (bronchodilation + decreased mucous production)
96
Ipratropium Bromide
Reliever (short acting): Muscarinic Antagonists (suppresses parasympathetic activity, leading to bronchidilation and decreased mucous production)
97
Tiotropium Bromide
Symptom Controller (long acting): Muscarinic Antagonist (suppresses parasympathetic activity, leading to bronchodilation and decreased mucous production)
98
Montelukast
Both preventer and reliever: Leukotriene receptor antagonist (anti-inflammatory)
99
Zafirlukast
Both preventer and reliever: Leukotriene receptor antagonist (anti-inflammatory)
100
Sodium cromoglycate
Both preventer and reliever: Chloride channel blocker. Stabilizes mast cells
101
Nedocromil Sodium
Both preventer and reliever: chloride channel blocker. Stabilises mast cells.
102
Theophylline
Both preventer and reliever: Xanthine bronchodilator (long acting bronchodilator used in persistent asthma, has to be used 4d)
103
Aminophylline
Both preventer and reliever: Xanthine bronchidilator (long acting bronchodilator used in persistent asthma, has to be used 4d)
104
Indomethacin, Naproxen, Aspirin, Ibuprofen, paracetamol, diclofenac
NSAIDS: non-steroidal anti-inflammatory drugs
105
Celecoxib, Rofecoxib, Lumiracoxib
COX2 Inhibitors: Anti-inflammatory
106
Action of Class I
Slow depolarisation (phase 0) by blocking fast Na+ channels. This slows depolarisation, thus slowing rate of contractions. Thus can help to prevent arrhythmias. Lognocaine has rapid dissociation time, and binds to both open and closed channels, thus it has the lowest pro-arrhythmic affect because by dissociating quickly, it effecitvely differentiates between normal and abnormal cardiac cells: normal cells will not be slowed by lignocaine, only abnormally behaving cells.
107
What to BBs do?
Antagonise SNS activity by binding to B1 and B2 receptors. B1 antagonists - block NA/A from binding, causing cardiac muscle relaxation. B2 antagonists - block NA/A from binding, thus contract smooth muscle.
There are non-selectives and B1 selectives. All non selectives at high enough concentrations. Negative inotrope and neg chronotrope as mainly act by inhibiting Ca+ entry into the cell. Thus good for HTN, angina....
