Drug performas Flashcards

(41 cards)

1
Q

Paracetamol drug name

A

acetaminophen/N-(4-hydroxyphenyl)ethanamide

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2
Q

Paracetamol trade names

A

Tylenol
Calpol
Panadol

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3
Q

Paracetamol indications

A

Mild pain

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4
Q

Paracetamol how does it work

A

Inhibits production of prostaglandins which cause pain and inflammation (mainly in the brain)

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5
Q

Paracetamol side effects

A
Allergic reaction
Rash
Swelling
Flushing
Low bp
fast heartbeat
rare
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6
Q

Contraindications paracetamol

A
Hypersensitivity
analgesic nephropathy
renal disease
hepatic impairment
alcohol abuse
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7
Q

Paracetamol interactions

A

Alcohol - mild sedation, liver damage
Anticoagulants - increases effect
anti-convulsants
some antibiotics (amlodipine)

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8
Q

Paracetamol elimination

A

Kidneys - urine

98% eliminated in 24 hrs

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9
Q

Paracetamol advice

A

relieves pain and fever
2x tablets every 4-6 hours
no more than 8 in 24 hours

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10
Q

Ibuprofen drug name

A

(RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid

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11
Q

Ibuprofen trade name

A
advil
motrin
medipren
nurofen
proposal
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12
Q

Ibuprofen indications

A

Mild pain

Fever

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13
Q

Ibuprofen how does it work

A

blocks prostaglandin to reduce pain and swelling

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14
Q

Ibuprofen side effects

A
Vomiting
heart burn
bloating
gas
diarrhoea
constipation
dizziness
gi ulcer
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15
Q

Ibuprofen contraindications

A

asthma that is NSAID/aspirin sensitive
known hypersensitivity
active GI bleeding
peptic ulcer

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16
Q

Ibuprofen interactions

A
NSAIDs
Aspirin
corticosteroids
antihypertensives
anticoagulants
diuretics
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17
Q

Ibuprofen excretion

A

urine

24 hours

18
Q

Ibuprofen advice

A

take with meal or snack

19
Q

Co-codamol trade names

A

panadeine
codibar
tylex

20
Q

Co-codamol uses

A

mild to severe pain
children over 12
short term relief

21
Q

Co-codamol how does it work

A

reduces production of prostaglandins in the brain and spinal cord
mild opioid -small amount converted to morphine

22
Q

Co-codamol side effects

A
constipation
nausea
vomiting
dizziness
light headedness 
infection
addiction
23
Q

Co-codamol contraindictions

A

known hypersensitivity
conditions where morphine/opioids are contraindicated
0-18 undergone tonsillectomy
breastfeeding

24
Q

Co-codamol interactions

A
alcohol
some antibiotics 
antihistamines
anaesthetics
anticholinergics (block acetyl choline)
25
Co-codamol elimination
Absorbed from GI tract metabolised in liver excreted in urine as glucuronic acid
26
Co-codamol advice
don't take anything else 2x every 4-6 hours no more than 8 in 24 hrs do not drive until you know how it affects you
27
Chlorphenamine actions
relieves sinus congestion, watery eyes, runny nose, itchy throat, sneezing, due to colds, allergies, hay fever
28
Chlorphenamine tradenames
Puritan | Qdall AR
29
Chlorphenamine how does it work
prevents actions of histamine
30
Chlorphenamine side effects
``` dizziness drowsiness dry mouth/nose/throat blurred vision restlessness ```
31
Chlorphenamine contraindications
known hypersensitivity to antihistamines, lactose, magnesium monoamine oxidase inhibitor in last 14 days
32
Chlorphenamine interactions
alcohol sedatives opioids neuroleptics
33
Chlorphenamine elimintation
metabolised and excreted primarily in urine
34
Chlorphenamine advice
eases allergic reactions | common side effects are sleepiness - may affect driving
35
Gaviscon trade names
tums | maalox
36
What is gaviscon made of
aluminum hydroxide and magnesium carbonate
37
Gaviscon how does it work
neutralises stomach acid to treat heartburn and sour stomach by forming a protective raft on top of the stomach when it comes into contact with acid
38
Gaviscon side effects
nausea, constipation, diarrhoea, headaches
39
Gaviscon contraindictions
``` calcium carbonate sodium hyroxide magnesium stomach or intestinal blockage constipation haemorrhoids ```
40
Gaviscon interactions
phosphate supplements (often contain potassium) calcium supplements other aluminium and calcium antacids
41
Gaviscon elimination
faeces - GI tract