Drug Quiz 3 Flashcards
(28 cards)
lithium Brand? TC? MOA? AE?
Brand: Lithonate, Lithotabs, Lithobid
TC: Antimanic agent
MOA: unknown (antagonism of NE/Dopamine from nerve terminals/increasing reuptake and inactivation of catecholamines
AE: diarrhea, vomiting, drowsiness, blurry vision, tinnitus
gabapentin Brand? TC? MOA? AE?
Brand: Neurontin
TC: Anticonvulsant/antineuralgic
MOA: unknown
AE: somnolence, dizziness, ataxia
pregabalin Brand? TC? MOA? AE?
Brand: Lyrica
TC: Anticonvulsant
MOA: unknown (related to high binding affinity to the alpha(2)-delta site in CNS tissue?
AE: dizziness, somnolence, dry mouth
primidone Brand? TC? MOA? AE?
Brand: Mysoline
TC: Anticonvulsant
MOA: unknown (raise electro-chemoshock seizure thresholds)
AE: ataxia, dizziness
phenobarbital Brand? TC? MOA? AE?
Brand: Phenobarbital
TC: Anticonvulsant
MOA: inhibition of conduction in reticular formation
AE: somnolence, light-headedness, residual sedation
phenytoin Brand? TC? MOA? AE?
Brand: Dilantin, Kapseals
TC: Anticonvulsant
MOA: Increase the extrusion of sodium ions
AE: ataxia, slurred speech, mental confusion
oxcarbazepine Brand? TC? MOA? AE?
Brand: Trileptal, Oxtellar XR
TC: Anticonvulsant
MOA: Block Na channels, inhibition of repetitive neuronal firing and propagation impulses
AE: dizziness, somnolence, fatigue
levetiracetam Brand? TC? MOA? AE?
Brand: Keppra
TC: Anticonvulsant
MOA: unknown (inhibits burst firing in hippocampus to prevent propagation of seizure activity)
AE: somnolence, asthenia, dizziness
topiramate Brand? TC? MOA? AE?
Brand: Topamax, Trokendi XR
TC: Anticonvulsant
MOA: exact unknown (action potential depolarization, increase frequency of GABA-A receptor activation, antagonizes ability of Kainate to activate Kainate/AMPA subtype of excitatory amino acid receptor)
AE: fatigue, nervousness, difficulty with concentration
carbamazepine Brand? TC? MOA? AE?
Brand: Tegretol (XR), Carbatrol ER, Equetro ER
TC: Anticonvulsant
MOA: reducing polysynaptic responses and blocking post-tetanic potentiation
AE: dizziness, unsteadiness, drowsiness
divalproex Brand? TC? MOA? AE?
Brand: Depakote (ER)
TC: Anticonvulsant/bipolar agent
MOA: unknown (increased brain levels of GABA)
AE: asthenia, somnolence, dyspepsia
lamotrigine Brand? TC? MOA? AE?
Brand: Lamictal, Lamictal XR
TC: Anticonvulsant/bipolar agent
MOA: unknown (inhibition of sodium channels)
AE: rash, dizziness, somnolence
sertraline Brand? TC? MOA? AE?
Brand: Zoloft
TC: Antidipressant
MOA: inhibits reuptake of serotonin (5HT), very weak actions against NE/dopamine (SSRI)
AE: dry mouth, dyspepsia, tremor, sweating
paroxetine Brand? TC? MOA? AE?
Brand: Paxil (XR), Pexeva
TC: Antidepressant
MOA: inhibits reuptake of serotonin (5HT), very weak actions against NE/dopamine (SSRI)
AE: somnolence, asthenia, insomnia, sweating
buproprion Brand? TC? MOA? AE?
Brand: Wellbutrin (SR,XL), Zyban
TC: Antidepressant
MOA: weakly inhibits norepinephrine and dopamine reuptake
AE: dizziness, constipation, weight loss, tremor
fluoxetine Brand? TC? MOA? AE?
Brand: Prozac, Sarafem
TC: Antidepressant
MOA: inhibits reuptake of serotonin, but not norepinephrine (SSRI)
AE: nervousness, sweating, fatigue
trazodone Brand? TC? MOA? AE?
Brand: Desyrel
TC: Antidepressant
MOA: inhibits reuptake of serotonin
AE: hypotension, dizziness, dry mouth, priapism
duloxetine Brand? TC? MOA? AE?
Brand: Cymbalta
TC: Antidepressant
MOA: inhibit reuptake of norepinephrine and serotonin at presynaptic nerve terminals (SNRI)
AE: dry mouth, constipation, dizziness
desvenlafaxine Brand? TC? MOA? AE?
Brand: Pristiq
TC: antidepressant
MOA: inhibit reuptake of norepinephrine and serotonin at presynaptic nerve terminals (SNRI)
AE: dry mouth, constipation, drowsiness
venlafaxine Brand? TC? MOA? AE?
Brand: Effexor (XR)
TC: Antidepressant
MOA: inhibit reuptake of norepinephrine and serotonin at presynaptic nerve terminals (SNRI)
AE: dry mouth, constipation, dizziness
mirtazapine Brand? TC? MOA? AE?
Brand: Remeron
TC: Antidepressant
MOA: antagonist of serotonin 5HT2/5HT3 receptors, also inhibitor of H1 and adrenergic alpha 1/muscarinic receptors
AE: drowsiness, increased appetite, weight gain, dry mouth
vilazodone Brand? TC? MOA? AE?
Brand: Viibryd
TC: Antidepressant
MOA: inhibits reuptake of serotonin (5HT) (SSRI), partial agonist of serotonergic 5-HT receptors
AE: diarrhea, dizziness, dry mouth
citalopram Brand? TC? MOA? AE?
Brand: Celexa
TC: Antidepressant
MOA: inhibits reuptake of serotonin (5HT), NO actions against NE/dopamine (SSRI)
AE: dry mouth, somnolence, impotence
escitalopram Brand? TC? MOA? AE?
Brand: Lexapro
TC: Antidepressant
MOA: inhibits reuptake of serotonin (5HT), NO actions against NE/dopamine (SSRI)
AE: insomnia, ejaculation disorder, somnolence
