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Drug reactions Flashcards

(59 cards)

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1
Q

Drugs that cause hypothyroidism

A

Lithium

Amiodarone

Sulfonamides

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2
Q

Drugs that cause acute hepatitis and jaundice

A

Erythromycin

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3
Q

Drugs that cause diarrhea

A

Metformin, Erythromycin, Colchicine, Orlistat, Acarbose

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4
Q

Drugs that cause hepatic necrosis

A

Rifampin, isoniazid, pyrazinamide, statins, fibrates

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5
Q

Drugs that cause pancreatitis

A

Didanosine

Corticosteroids

Alcohol

Valproic Acid

Azathioprine

Diuretics

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6
Q

Drugs that cause agranulocytosis

A 
Ganciclovir
Clozapine
Carbamazepine
Colchicine
Methimazole
Propylthiouracil
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7
Q

Drugs that cause hyperglycemia

A 
Tacrolimus
Protease inhibitors
Niacin
HCTZ
Corticosteroids
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8
Q

Drugs that cause aplastic anemia

A

Carbamazepine, Methimazole, Propylthiouracil, NSAIDs, Benzene, Chloramphenicol

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9
Q

Hemolytic anemia

A

Methyldopa, PCN

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10
Q

Drugs that cause hemolysis with G6PD deficiency

A

Hemolysis IS D PAIN

Isoniazid
Sulfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
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11
Q

Drugs that cause megaloblastic anemia

A

Having a BLAST with PMS

Phenytoin
Methotrexate
Sulfa drugs

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12
Q

Drugs that cause fat redistribution

A

Protease inhibitors, Glucocorticoids

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13
Q

Drugs that cause gingival hyperplasia

A

Phenytoin, CCBs, Cyclosporine

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14
Q

Drugs that cause gout

A 
Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporine

“Painful Tophi and Feet Need Care”

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15
Q

Drugs that cause myopathy

A

Fibrates, niacin, colchicine, hydroxychloroquine, IFN-alpha, penicillamine, statins, glucocorticoids

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16
Q

Drugs that cause photosensitivity

A

Sulfonamides
Amiodarone
Tetracyclines
5-FU

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17
Q

Drugs that cause Stevens-Johnson

A

Anti-epileptics
Allopurinol
Sulfa drugs
PCN

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18
Q

Drugs that cause SLE-like syndrome

A 
Sulfa drugs
Hydralazine
Isoniazid
Procainamide
Phenytoin
Etanercept
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19
Q

Drugs that cause tendon/cartilage damage

A

Fluoroquinolones

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20
Q

Drugs that cause seizures

A

Isoniazid (B6 def)
Bupropion
Imipenem/cilastatin
Enflurane

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21
Q

Drugs that cause DI

A

Lithium

Demeclocycline

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22
Q

Drugs that cause hemorrhagic cystitis

A

Cyclophosphamide
Ifosfamide

both chemo drugs

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23
Q

Drugs that cause interstitial nephritis

A

Methicillin, NSAIDs, Furosemide

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24
Q

Drugs that cause SIADH

Study These Flashcards
A

“Can’t Concentrate Serum Sodium”

Carbamazepine
Cyclophosphamide
SSRIs

Also: chlorpropamide (sulfonylurea), lung dz (pna, tb, ventilator use)

25
Drugs that cause pulmonary fibrosis
"Breathing Air Badly from Medications" Bleomycin Amiodarone Busulfan Methotrexate (chemo drugs, except amiodarone)
26
Drugs that cause disulfiram like rxns
``` Metronidazole Cephalosporins Griseofulvin Procarbazine Sulfonylureas ```
27
Reversal of thrombolytics (eg TPA)
Aminocaproic acid
28
Heparin reversal
Protamine sulfate
29
Drugs that cause aplastic anemia
Carbamazepine, Methimazole, Propylthiouracil, NSAIDs, Benzene, Chloramphenicol
30
Hemolytic anemia
Methyldopa, PCN
31
Drugs that cause hemolysis with G6PD deficiency
Hemolysis IS D PAIN ``` Isoniazid Sulfonamides Dapsone Primaquine Aspirin Ibuprofen Nitrofurantoin ```
32
Drugs that cause megaloblastic anemia
Having a BLAST with PMS Phenytoin Methotrexate Sulfa drugs
33
Drugs that cause fat redistribution
Protease inhibitors, Glucocorticoids
34
Drugs that cause gingival hyperplasia
Phenytoin, CCBs, Cyclosporine
35
Drugs that cause gout
``` Pyrazinamide Thiazides Furosemide Niacin Cyclosporine ``` "Painful Tophi and Feet Need Care"
36
Drugs that cause myopathy
Fibrates, niacin, colchicine, hydroxychloroquine, IFN-alpha, penicillamine, statins, glucocorticoids
37
Drugs that cause photosensitivity
Sulfonamides Amiodarone Tetracyclines 5-FU
38
Drugs that cause Stevens-Johnson
Anti-epileptics Allopurinol Sulfa drugs PCN
39
Drugs that cause SLE-like syndrome
``` Sulfa drugs Hydralazine Isoniazid Procainamide Phenytoin Etanercept ```
40
Drugs that cause tendon/cartilage damage
Fluoroquinolones
41
Drugs that cause seizures
Isoniazid (B6 def) Bupropion Imipenem/cilastatin Enflurane
42
Drugs that cause DI
Lithium | Demeclocycline
43
Drugs that cause hemorrhagic cystitis
Cyclophosphamide Ifosfamide both chemo drugs
44
Drugs that cause interstitial nephritis
Methicillin, NSAIDs, Furosemide
45
Drugs that cause SIADH
"Can't Concentrate Serum Sodium" Carbamazepine Cyclophosphamide SSRIs
46
Drugs that cause pulmonary fibrosis
"Breathing Air Badly from Medications" Bleomycin Amiodarone Busulfan Methotrexate (chemo drugs, except amiodarone)
47
Drugs that cause disulfiram like rxns
``` Metronidazole Cephalosporins Griseofulvin Procarbazine Sulfonylureas ```
48
Reversal of thrombolytics (eg TPA)
Aminocaproic acid
49
Heparin reversal
Protamine sulfate
50
Drugs that cause hypocalcemia
bisphosphonates, loop diuretics, foscarnet (also causes hypokalemia, hypomagnesemia, hypophosphatemia)
51
Daptomycin side effect?
rhabdomyolysis | lipopeptide used to treat G-
52
Gingival hyperplasia is a side effect of ____
phenytoin (in 50% of pts)
53
phenytoin AEs
CNS sx (ataxia, nystagmus) gingival hyperplasia, coarsening of facial features, hirsutism interferes with folic acid metabolism --> megaloblastic anemia P450 inducer
54
Lithium AEs
neuromuscular excitability, nephrogenic DI, hypothyroidism, cardiac conduction defects
55
Isoniazid - severe AE?
hepatitis
56
Drug that can cause pancreatitis?
didanosine (NRTI)
57
Drugs that cause acute tubular necrosis
aminoglycosides, lead, cisplatin, radiocontrast media, amphotericin B, foscarnet
58
Drugs that can precipitate in kidney tubules and cause obstruction?
sulfonamides, methotrexate, acyclovir, triamterene
59
Toxicity of hydroxychloroquine?
irreversible retinopathy long-term users (eg mild RA, SLE) should have regular ophtho exams

Pharmacology (4 decks)

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