Drug side effects Flashcards

1
Q

NSAIDs

A

No Urine (RF)
Systemic dysfunction/ HF
Asthma
Indigestion
Dyschiariasis aka blood clotting

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2
Q

Antihypertensive general side effects
1- BB/ CCB
2- ACE-i/ diuretics

A

Hypotension
1- Bradycardia
2- Electrolyte disturbances

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3
Q

What is a common side effect of BB?

A

Wheeze

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4
Q

What is a common side effect of ACE-i

A

dry cough

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5
Q

What is a common side effect of CCB

A

Peripheral oedema

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6
Q

What is a common side effect of diuretics ( thiazide or potassium sparing)

A

Thiazide : Gout
Potassium sparing: Gynaecomastia

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7
Q

What drugs should be avoided with methotrexate?

A

NSAIDs
Trimethoprim
Infection

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8
Q

What are the common side effects of steroids?

A

Stomach Ulcers
Thin skin
Edema
Right and left HF
Osteoporosis
Infection
Diabetic complications:

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9
Q

What drugs should be stopped before surgery?

A

I LACK OP
Insulin
Lithium
Anticoagulants
K- sparing diuretics
Oral hypoglycemics
Peridopril and other ACE-i

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10
Q

Drugs associated with increased confusion

A

Diazepam
Co-codamol
Glucocorticoids
trazodone?

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11
Q

Digoxin

A

Confusion
Nausea
Visual halos
Arrythmias

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12
Q

Lithium

A

Tremor
Tiredness
Arrythmias/ seizures/ coma/ RF/ Diabetes Insipidus

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13
Q

Phenytoin

A

Gum hypertrophy
ataxia
nystagmus
peripheral neuropathy
teratogenicity

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14
Q

What medication should you adjust in addisonian patients when they are sick?

A

Increase their dose of steroids

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15
Q

When would you use butamenide in the treatment of HF?

A

Cases of resistant HF to furosemide

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16
Q

What is a common side effect of carbimazole?

A

Neutropenia

17
Q

Enzyme inducing drugs and progesterone only contraceptives?

A

Use the parenteral form.

18
Q

PreScriber format??

A

Patient details
Re: reaction/allergy
Sign
Check contraindications
Route of each drugs
Iv fluids if needed
Blood clot prophylaxis
Emetics
Relief for pain

19
Q

when would you prescribe an ACE-i( time of day)

A

At night- as it can cause postural hypotension

20
Q

List Enzyme Inhibitors (aka drugs which encourage bleeding on Warfarin)

A

PC40 inhibitors
AODDEVICES
- Allopurinol
-Omeprazole
-Disulfiram
-Eryhthromycin
-Valproate
-Isoniazid
-Ciproflaxacin
-Ethanol
-Sulphonamides

21
Q

List of enzyme inducers

A

PC BRAS
- Phenyyoin
- Carbamezapine
- Barbituates
- Rifampicin
- Alcohol
- Sulfonylureas

22
Q

When would a man be on Tamoxifen?

A

Treatment of prostate/ breast cancer

23
Q

Which Anti-HTN between a bb and a thiazide-type diuretic would you stop and why?

A

Thiazide type diuretic- has no effect on HR AKA down not slow it down.
Also usually stopped before surgery anyways as can cause gout

24
Q

First line drugs for treatment of acute ex of COPD?

A

Salbutamol + SABA e.g. Ipratropium bromide

25
Q

side effect of olanzapine?

A

Increases QTc

26
Q

what medication improves the skin side effects of a rash?

A

Chloranphenamine

27
Q

A 1% solution (g in ml?)

A

1 g in 100 ml

28
Q

contraindication to laxido?

A

Bloating

29
Q

drugs avoided in peripheral arterial disease?

A

Beta-Blockers

30
Q

drugs which predispose to candida?

A

Steroids
Amoxi
clari

31
Q

Drugs which might cause urinary retention?

A

Anti-cholinergics
General anaestetics
Alpha-adrenoreceptor agonists
Benzodiazapenes
NSAIDs
CCBs
Anti-histamines
Alcohol

32
Q

Measure used to measure function of HRT?

A

Blood pressure

33
Q

Hypoglycemia treatment

A

20% glucose. 100mls over 15mins

34
Q

First line for treating an acute dystonic reaction?

A

Procyclidine hydrochloride

35
Q

Drugs commonly associated with hyperkalemia?

A

Dalteparin sodium/ Enoxaparin
ACE-i/ARBs
Mycophenolate
Diclofenac
Potassium sparing diuretics e.g. spironolactone
Trimethoprim

36
Q
A

t