Drug Synergy Flashcards

1
Q

What is atripla

A

comprises of three drugs efavirenz (NNRTI), tenofovir (NtRTI) and entricibatine (NRTI) that are used in HAART therapy to treat HIV

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2
Q

What is a CCR5 inhibitor

A

Maraviroc

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3
Q

What is a gp41 inhibitor

A

Enfuvirtide

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4
Q

What are two integrase inhibitors

A

Raltegravir and Elvitegravir

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5
Q

What are drugs are used in combination to treat Hep C

A

Sofosbuvir, PEG interferon and Ribavarin

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6
Q

Two antibiotics that act together to promote increased death of Staph and enterococcus

A

Gentamicin/Aminoglycoside and penicillin

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7
Q

two drugs used together to restrict fungal growth

A

Flucytosine and amphotericin

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8
Q

Two drugs used together to inhibit the DNA synthesis pathway

A

Trimethoprim and Sulfonamides

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9
Q

Two drugs used to inhibit Prostate cancer

A

Cisplatin and etoposide

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10
Q

Immunsuppressants used in synergy

A

Glucocorticoids, cytotoxic drugs, calcineuron inhibitors, and antibody therapy targetted towards inhibiting cytokine receptors, t-lymphocyte depletion and co-stimulation block

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11
Q

What antibody is an anti-IL-2R

A

Daclizumab

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12
Q

What antibody is targetted against T cells

A

Anti-thymocyte globulin

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13
Q

What Fusion protein is against Co-stimulation of APCs

A

Abatacept (CTLA-4fusion)

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14
Q

What HIV drugs as NNRTI

A

Zalovudine (AZT) and Zalcitabine

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