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Fucking Hell > Drugs > Flashcards

Drugs Flashcards

(54 cards)

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1
Q

Amphetamine

A

Mixed salts (Adderall),
dexamphetamine,
lisdexamphetamine

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2
Q

Methylphenidate

A

Ritalin
Concerta

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3
Q

Atomoxetine

A

Ne>serotonin>dopamine

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4
Q

Guanfacine

A

Lowers Blood pressure
ADHD

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5
Q

Benzo for anxiety

A

Diazepam
Xanax: GAD, Panic
Ativan: surgery

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6
Q

Citalopram

A

SSRI; PDA, SAD

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7
Q

Escitalopram

A

SSRI; all

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8
Q

Prozac

A

Fluoxetine, SSRI; panic only

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9
Q

Fluvoxamine

A

SSRI; panic and social

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10
Q

Paroxetine

A

SSRI; all

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11
Q

Sertraline

A

SSRI; all

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12
Q

Duloxetine

A

SNRI; GAD only

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13
Q

Venlafaxine

A

SNRI; all

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14
Q

Buspirone

A

Anxiety: GAD
Presynaptic 5-HT1A agonist,
D2 antagonist.

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15
Q

Apo-clomipramine

A

Tricyclic antidepressant

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16
Q

Depression - MOAI

A

Nardil
Pamate
Menerix

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17
Q

Anxiety

A
  1. Benzo
  2. SSRI & SNRI
  3. Buspirone
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18
Q

ADHD

A
  1. Amphetamine
  2. Metheylphenidate
  3. Atomoxetine
  4. Guanfacine
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19
Q

Bipolar Disorder

A
  1. Anticonvulsant
  2. Atypical antipsychotics
  3. Antidepressant
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20
Q

Valoproate

A

Anticonvulsant - Bipolar disorder
GABA increase

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21
Q

Lamotrigine

A

Anticonvulsant, bipolar disease
Glutamate decrease

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22
Q

Carbamazepine

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A

Anticonvulsant; bipolar

23
Q

Lithium

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A

Anticonvulsant; bipolar
- antioxidant defense
- increase GABA
- inhibit DA and GLU
- increase grey matter

24
Q

Olanzapine

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A

Bipolar disorder
Rapid

25
Quetiapine
Bipolar disorder Acute mania and depressjon
26
Anticonvulsant for Bipolar Disorder
1. Valproate 2. Lamotrigine 3. Carbamazepine 4. Lithium
27
Atypical Antipsychotics for Bipolar Disorder
1. Olanzepine 2. Quetiapine
28
Schizophrenia
1. Typical antipsychotics 2. Atypical antipsychotics
29
Typical antipsychotics
1. Chlorpromazine 2. Haloperidol - positive symptoms - extrapyramidal effect - neuroleptic malignant syndrome - peolactin release
30
Atypical antipsychotics For schizophrenia
1. Clozapine 2. Quetiapine 3. Aripiprazole (3rd gen)
31
Epilepsy
1. Modulation of votage gated ion channels 2. Inhibition of synaptic excitation: inhibit Glutamate 3. Enhancement of synaptic inhibition: increase GABA
32
Epilepsy: Modulation of votage gated channels
1. Inhibition of Na+ channel - phenytoin - carbamazepine - valproic acid - topiramate 2. Inhibition of T-type Ca2+ channel - ethosuximude 3. K+ channel activation
33
Epilepsy 2. Inhibition of synaptic excitation: glu
Inhibit 1. L-type Ca2+: gabapentine 2. SV2A : levetiacetam, brivaracetam 3. AMPA or kainate: perampanel, topiramate
34
Epilepsy 3. Enhancement of synaptic inhibition: GABA
1. PAM of GABA: benzo, barbi, topiramate! 2. Inhibition of GABA-T: vigabatrin (blindness)
35
Migraine
1. 5-HT1 receptor agonist 2. NSAIDs 3. CGRP ab
36
Migraine drugs: 1. 5-HT1 agonist
1. Ergot Alkaloids - ergotamine 2. Triptan - sumatriptan, zolmitriptian
37
NSAIDs
Arachidonic acid - prostagladin - //- prostanoid (COX-1 or COX-2) mediated
38
CGRP
Binds CLR/RAMP1 , NO production and glutamate increase — vasodilation, pain
39
CGRP drug - ab
Erenumab - ab for CGRP receptor Galcanezumab - ab for CGRP
40
Alzheimers Disease
1. NMDA antagonist; memantine 2. Anti-AChE - donepezil - galantamine - rivastigmine 3. Antibody for beta-amyloid - aducanumab
41
Parkinsons disease 1. L- DOPA (+) 2. Dopamine agonist 3. MAO-B inhibitor
1. L Dopa, carbidopa, entacapone 2. Pramipexole Ropinirole Apomorphine 3. Selegiline Rosagiline
42
Barbiturates
1. Phenobarbitaturate: tonic-clonic 2. Pentobarbital- animal euthanasia
43
Benzodiazepine
1. Short acting - xanax - ativan - flunitrozepam 2. Long acting: diazepam 3. Z drugs - zolpidem - zolpiclone
44
Opioids
Morphine, codeine, oxycodone, fentanyl
45
Opioid overdose drug
1. Acute: narcan - mu antagonist 2. Chronic: - buprenorphine (partial agonist - methadone (full agonist - naltrexone (competitive antagonist
46
Alcohol abuse treatment
Diazepam Acamprosate Naltrexone
47
Diazepam
Benzodiazepine. Anxiolytic, anticonvulsant Acute alcohol withdrawal symptom
48
Quetiapine
Atypical antipsychotic. Bipolar disorder Schizophrenia
49
Topiramate
All epilepsy treatment
50
Naltrexone
Opioid chronic abuse treatment ( mu competitive antagonist) Alcohol restraint in NAc and VTA
51
Carbamazepine
inhibit Na+ channel Anticonvulsant in Bipolar disorder Epilepsy
52
Status epilepticus
Epilepsy 5 min
53
Migraine
Premonitory, aura, headache, postdrome
54
Neuroleptic malignant syndrome
Increased heart rate Typical antipsychotics side effect

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