Drugs Flashcards
(39 cards)
Aspirin
NSAID:
CV prophylactically, antipyretic, analgesic, colon CA prevention, anti-inflammatory
Diflunisal
NSAID:
more potent than ASA
no antipyretic activity (doesn’t cross BBB)
Oxaprozin
NSAID:
anti-inflammatory
analgesic
antipyretic
Ibuprofen (motrin)
NSAID:
anti-inflammatory
analgesic
antipyretic
Naproxen
NSAID:
anti-inflammatory
analgesic
antipyretic
Flubiprofin
NSAID:
anti-inflammatory
analgesic
antipyretic
Indomethacin
NSAID: Gouty arthritis OA potent anti-inflammatory (worse GI and CNS effects)
Sulindac
NSAID:
less potent than indomethacin
Etodolac
NSAID:
less GI problems
Diclofenac
NSAID: RA OA Ankylosing spondilitis (more potent than indomethacin or naproxen)
Nabumatone
NSAID:
RA
OA
Piroxicam
NSAID
Meloxicam
NSAID
-cox2 selective
Ketorolac
NSAID:
post surgery
-injectable
Celecoxib
NSAID:
cox2 inhibitor
Acetaminophen (tylenol)
inhibits PG only in CNS -analgesic -antipyretic (not anti-inflammatory) {glutathione} antidote = n-acetylcysteine
Morphine
Opiate: mu receptor
analgesia
rarely: diarrhea & cough
ADR: resp and circulatory depression, constipation, euphoria, miosis
meperidine
Opiate: kappa receptor antimuscarinic activity post surgery (do not use with chronic pain = develop seizure) monitor: s/s of jerking or twitching
Methadone
Opiate: mu receptor
analgesic
-morphine or heroin withdrawal
-chronic pain control
Fentanyl
Opiate:
IV = post op
Patch = chronic pain
Codeine
Opiate:
prodrug metabolized to morphine
Oxycodone
Opiate:
combine with ASA or Acetaminophen
Hydrocodone
Opiate:
combine with ASA or Acetaminophen
Propoxyphene
Opiate:
low analgesic activity
related to methadone