Drugs Flashcards
(184 cards)
Why would Pyroxidine be prescribed?
Prevent side effect of Isoniadzid (peripheral neuropathy)- TB mediation
What are the side effects of Phenytoin?
Gingival hyperplasia, peripheral neuropathy, lymphadenopathy
How does Memantine work?
NMDA antagonist - second line treatment for alzheimers
What enzyme needs to be tested prior to started Aziothiarpine? and what is Azathioprine used for?
TPMT levels prior to staring treatment. Azathioprine is used to induce remission in Crohns
Side effects of calcium channel blockers? eg Amlodipine
Ankle swelling
What is the reversal agent for Dabigitran (DOAC)?
idarucizumab
What is the reversal agent for Heparin?
protamine sulfate
What are some examples of anti musclarinics used in urge incontinence?
First line: Oxybutanin. Second line: tolterodine
What monitoring is required with use of Amiodarone?
LFTS/ TFTS/ U+Es 6 monthly. ECG every 12 months
What type of antibiotic is Clarithryomycin and what is a side effect?
Macrolide. Side effect is VT (torsades de points)
What morphine drugs can be used in patients with CKD 4 (palliative care)?
Alfentanil, oxycodone, buprenorphine, fentanyl
How does Gliclazide work?
ATP dependent K channels on pancreatic beta cells
What is a side effect of nicorandil?
Ulceration including anal ulceration
What monitoring is required for Hydroxychloroquine?
Ophthalmology referral prior to commencing treatment. Need annual visual check
What is a side effect of Co-amoxiclav?
Can cause cholestasis- elevated bilirubin/ itching
What are the side effects of Cisplatin?
Hypomagnesium, ototoxicity and peripheral neuropathy
What are the side effects of Methotrexate?
Bone marrow suppression, liver fibrosis, lung fibrosis.
What are the side effects of Doxorubcin?
Cardiomyopathy
What would a side effect of long term oral trimethoprim for acne be?
Depress haemopoetisis
What type of drug is Losartan ?
ARB
What drugs can cause hypercalcaemia?
Thiazide drugs eg Bendroflumethazide or calcium containing antiacids
What type of drug is Carvedilol?
B blocker. Used post MI
What type of drug is Gliclazide and what are some of the side effects?
Sulphonylurea.
SI include weight gain and hypoglycaemia
What type of drug is Bumetanide? and what is the side effect?
Loop Diuretic
Ototoxicity