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10. Asthmas > Drugs > Flashcards

Drugs Flashcards

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1
Q

Drug classes use for short term management

A
  • Short acting beta-agonist (min)

- PO/IV corticosteroids (hours)

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2
Q

Drugs belong to SABA

  • Agents
  • MOA
  • ADEs
A
  • Albuterol
  • Fenoterol
  • Levalbuterol
  • MOA: activates adenylate cyclase which increase cAMP (antagonism of bronchoconstriction)
  • ADEs: palpitation, tachycardia, tremor, light-headedness, nervousness, HA and nausea
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3
Q

Xopenex

  • Class:
  • Dose/age
  • Expiration
    • Open up foil
    • Open up but leave in foil
A

Lavalbuterol

  • Form: HFA, Neb
  • Class: SABA
  • > 12 y.o: 0.63 mg TID
  • 6-12 y.o: 0.31 mg TID
  • Open up foil: good for 1 wk
  • Open up but leave in foil: good for 2 weeks

Xopenex HFA MDI

  • Class: SABA
  • Dose: 2inh (90mcg) q4-6h or 1 inh q4h
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4
Q
  • 1st line for persistent asthma:

- ADEs of inhaled corticosteroids

A
  • Corticorsteroid is 1st line for persistent asthma in adults and children. It have high anti-inflammatory effects

ADEs

  • Oral candidiasis, dysphonia, cough
  • To prevent: use spacer device and rinse mouth after
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5
Q

Aerospan

  • Form
  • Age limited:
A

Flunisolide

  • Form: HFA
  • Age limited: >/= 6 y.o
  • Come with built in space => no need to rec a spacer
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6
Q

Veramyst

  • Indication
A

Fluticasone furoate

  • Indication: allergic rhinitis, allergic conjunctivitis
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7
Q

Flonase

  • Indication
A

Fluticasone propionate

  • Indication: Allergic rhinitis
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8
Q

Dymista

  • Indication
A

Fluticasone + Azelastine

  • Indication: Allergic rhinitis
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9
Q

Alvesco

  • Age
  • Indication
A

Ciclesonide - Prodrug

  • Age: for greater than 12 y.o
  • Indication: Asthma
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10
Q

Omnaris

  • Dose
  • Indication
  • Ketoconazole
A

Ciclesonide

  • Omnaris: 2 spray per nostril QD
  • Indication: Allergic rhinitis
    => Ketoconazole increase systemic [ ] may lead to adrenal suppression
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11
Q

NasalCrom OTC

A

Cromolyn Nasal Sol’n

  • Class: Mast cell stabilizer
  • Indication: allergic rhinitis
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12
Q

Opticrom

  • Indication
A

Cromolyn

  • Indication: allergic conjuctivitis for year round rhinitis
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13
Q

Servent diskus

  • Class
A

Salmeterol DPI

Class: LABA

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14
Q

Foradil

  • Form:
  • Indication
  • Storage
A

Formoterol

  • Form: DPI
  • Prevention of exercise induced: 1 puff 10 min prior to exercise
  • Refrigerate the dry powder cap => dose BID
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15
Q

**Advair

  • Dose:
  • Exp after opened foil
A

Salmeterol + Fluticasone

  • Form: Diskus and HFA
  • After foil open: food for 1 month
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16
Q

**Symbycort

  • Form:
  • Indication
  • Exp after opened foil wrap
  • Age of use:
A

Formoterol + Budesonide: MDI

  • Asthmas & COPD maintenance
  • 2 puffs BID
  • The foil wrap protects if from moisture: after open is only good for 90 days
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17
Q

Dulera

  • Form
A

Formoterol + Mometasone:

  • Form: MDI
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18
Q

Singulair

  • Class
  • Indication
  • Frequency
A

Montelukast

  • Anti Leukotriences. Preceptor antagonist
  • Indication: allergy, asthma, exercise induce asthma
  • Frequency: QPM
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19
Q

Accolate

  • Class
  • Indicaiton
  • Adm
A

Zafirlukast

  • Anti-Leukotriences
  • Indication: ppx/tx of chronic asthma
  • Adm: BID on empty stomach (accolate = eat later)
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20
Q

Zyflo CR

  • Class
  • Indication
  • And
  • Monitor
A

Zileuton

  • Anti Leukotriences
  • Indicaiton: ppx/tx of chronic asthma
  • Adm: BID with Foods
  • Monitor: LFTs
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21
Q

Xolair

  • ADE:
  • Monitor:
  • Indication
  • Frequency
A

Omalizumab

  • Malignancies; anaphylaxis
  • Monitor: IgE and Eosinophril
  • Indication: allergic asthma, chronic idiopathic urticaria. Not for acute asthma
  • Frequency: 2-4 weeks SC
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22
Q

Inhaler w/ Lactose

A
  • Pulmicort Flexhaler
  • Serevent diskus
  • Flovent diskus
  • Asmanex
  • Advair Diskus
  • Foradil
  • Spiriva
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23
Q

Tornalate

  • Class
  • Indication
A

Bitolterol

  • Class B2 - Agonist
  • Indication: for preterm labor
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24
Q

Metaprel
ProMeta

  • Class
  • Indication
A

Metaproterenol

  • Class: beta-2 agonist
  • Indication: bronchoconstriction
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25
Brethine - Indication - SE risk:
Terbutaline - Class: beta-2 agonist - Indication: suppress contraction - ORAL: should not use for preterm tx: risk of cardiac problem. Have not shown to be effective - Injectable: should NOT use > 2-3 days for suppressing contraction due to serious maternal heart problems & death
26
Common agents use to treat Preterm Labor
- Magnesium sulfate (MgSO4) - Indomethacin - Nifedipine
27
Makena - Dose - Indication
Hydroxyprogesterone caproate - Dose: IM once a week from 16th to 37th week of pregnancy - Indication: preterm pregnancy
28
Drugs use for prevention of exercise induced bronchoconstriction
- LABA - Salmetrol - Formoterol: 1 puff 10 min prior to exercise - Montelukast - Cromolyn (Instal) - Singulair: 10mg PO 2H before exercise
29
Open foil expiration date: - Xopenex Nebulizer - Servent Diskus - Advair - Formoterol (Foradil) DPI: - Symbicort (budesonide & formoterol) - Combivent Respimat - Tudorza Pressair (Aclidinium): - Brovana (arformoterol neb)
- Xopenex Nebulizer: Open up foil plastic good for 1 week & opened foil but left inside good for 2 weeks - Servent Diskus: 6 weeks - Advair: 1 months - Formoterol (Foradil) DPI: 4 months from date of dispense (same as for Pradexa) - Symbicort (budesonide & formoterol): after open, only good for 90 days - Combivent Respimat: Write discard date on the label of the inhaler 3 months from the date the cartridge is inserted or when put on pharmacy label - Tudorza Pressair (Aclidinium): discard when 60 counter goes to 0 or 45 days after open or taking it out of the sealed pouch - Brovana (arformoterol neb): up to 6 weeks at RT
30
Which DPI can be dose QPM once daily or BID
- Asmanex - Mometasone
31
Strength for the following meds: - Advair: - Symbicort
- Advair: 100/50; 250/50; 500/50 (Steroid change but LABA stays same) - Symbicort: 80 mcg/4.5mcg; 160 mcg/4.5 mcg
32
In asthma and COPD med, all medications are in mcg excepto two med, which are they:
- Theophyllin | - Xolair
33
Ventolin - Brand/Form - Dose
Albuterol - Form: HFA - Dose: 1-2 puffs Q4-6H prn
34
Proventil - Generic/Form - Dose
Albuterol - Form: HFA - Dose: 1-2 puffs Q4-6H prn
35
ProAir - Generic/Form - Dose
Albuterol - Form: HFA - Dose: 1-2 puffs Q4-6H prn
36
AccuNeb - Generic/Form
Albuterol - Form: Neb Sol'n
37
VoSpire Generic/Dose
Albuterol Tab - Dose: 4-8 mg PO Q12H Max 16mg Q12H
38
Albuterol Tab - Form
- MDI - Syrup 2mg/5mL - IR: 2, 4 mg tab - ER: 4, 8 mg
39
QVAR - Form - Dose - Space:
Beclomethasone HFA Adult dose: - 40mcg 1-4 puffs BID - 80 mcg 1-2 puffs BID 5-11 years - 40 mcg: 1-2 puffs BID - No need spacer b/c the particle is small & will deposit into the lung
40
Beconase AQ - Indication: - Frequency
Beclomethasone - Indication: allergy rhinitis - Frequency: BID
41
Qnasl - Indication: - Frequency
Beclomethasone - Indication: Allergy rhinitis - Frequency: 2 spray into each nostril QD - For 12 y.o or older - Prime 4x
42
Pulmicord Flexhalder - Form - How to use it
Budesonide - Form: Dry powder => no need a spacer or shake - Inhale quick forceful inspiration
43
Pulmicort Respules - Form - Age limited
Budesonide - Form: Nebulizer - Age: as young as 12 mo old
44
Rhinocort - Indication
Budesonide - Allergic rhinitis
45
Entocort EC - Indication - Dose - Avoid
Budesonide - Indication: Crohn's Disease - Dose: 9mg PO QD - Avoid: grapefruit juice
46
Uceris - Indication - Dose - Avoid
Budesonide - Indication: ulcerative colitis - Dose: 9mg PO QD in AM - Avoid: grapefruit juice
47
Asmanex Twisthaler - Generic/form
Mometasone - Form: dry powder
48
Nasonex - Indication - Dose
Mometasone - Indication: allergic rhinitis - Dose: 2 prays in each nostril daily
49
Elocon - Form
Mometasone - Form: topical apply QD
50
Flovent - Form
Fluticasone - Form: MDI
51
Flovent Rotadisk - Form
Fluticasone - Form: DPI
52
Advair
Salmeterol + Flovent Rotadisk
53
Arnuity Ellipta - Form - Frequency - Age
Fluticasone - Form: DPI QD - Age: > 12 y.o
54
Zetonna - Dose - Indication - Ketoconazole
Ciclesonide - Zetonna: 1 spray/nostril QD - Indication: Allergic rhinitis => Ketoconazole increase systemic [ ] may lead to adrenal suppression
55
Flo-Pred
Prednisolone
56
Millipred
Prednisolone
57
Prelone
Prednisolone - Contain EtOH
58
Pediapred
Prednisolone
59
Orapred
Prednisolone ODT
60
Veripred 20
Prednisolone
61
Corticosteroid equivalent
- Cortisone 25mg - Hydrocortisone 20mg - Prednisolone 5mg - Prednisone 5mg - Methylprednisolone 4mg - Triamcinolone 4mg - Dexamethasone 0.75mg
62
Alocril
Nedocromil - I: allergic conjunctivitis
63
Elixophyllin - Form - MOA - Dose
Theophylline - methylxanthines - Form: Elixir = disulfram rxn - MOA: Increase cAMP & cGMP - Dose: 300-400mg/d. Max 900mg/d Swallow as a whole w/ full glass of water. Do not crush
64
Theo-24
Theophylline - methylxanthines
65
Theochron ER-12H
Theophylline - methylxanthines
66
Theophylline - methylxanthines Adult level: Children level:
Adult level: 5-15 mcg/mL | Children level: 5-10 mcg/mL
67
Theophylline - Aminophylline conversion
Theophylline = 80% of aminophylline dose
68
Nasocort
Triamcinolone

10. Asthmas (1 decks)

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