Drugs

Question 1

What does Bromocriptine do and what is it used to treat?

Answer 1

Action = Dopamine agonist

Tx for = Prolactinomas

Question 2

What does Desmopressin do and what is it used to treat?

Answer 2

Action = ADH analogue

Tx for = Central Diabetes Insipidus

Question 3

What does Tamoxifen do and what is it used to treat?

Answer 3

Action = Estrogen antagonist

Tx for = Breast cancer

Question 4

What does Perchlorate do and what is it used to treat?

Answer 4

Action = Na/I cotransporter inhibitor (on basolateral membrane)
Tx for = Hyperthyroidism (excess T3/T4)

Question 5

What does Thiocyanate do and what is it used to treat?

Answer 5

Action = Na/I cotransporter inhibitor (on basolateral membrane)
Tx for = Hyperthyroidism (excess T3/T4)

Question 6

What does Propylthiouracil (PTU) do and what is it used to treat?

Answer 6

Action = Inhibits thyroid peroxidase

Tx for = Hyperthyroidism (excess T3/T4)

Question 7

What does Metformin do and what is it used to treat?

Answer 7

Action = Upregulates insulin receptors on target tissues

Tx for = Type II Diabetes Mellitus

Question 8

What does Ketoconazole do and what is it used to treat?

Answer 8

Action = Inhibits steroid hormone synthesis

Tx for = Cushing’s Syndrome

Question 9

What does Metyrapone do and what is it used to treat?

Answer 9

Action = Inhibits steroid hormone synthesis

Tx for = Cushing’s Syndrome

Question 10

What does Spironolacetone do and what is it used to treat?

Answer 10

Action = Aldosterone antagonist

Tx for = Primary Hyperaldosteronism (Conn Syndrome)

Question 11

What does Octreotide do and what is it used to treat?

Answer 11

Action = Somatostatin analogue (inhibits GH)

Tx for = Acromegaly