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Flashcards in Drugs Deck (135)
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1

Guaifenesine (Robitussin)

Mucokinetic
Expectorant
Tx: dry cough

2

N-acetylycysteine (Mucomyst)

Mycolytic
Tx: COPD

3

Epinephrine

Beta agonist non-selective
BronchoD
Tx: any bronchoC or cardiac arrest

4

Terbutaline (Bricanyl)

B2 AG
BrochoD
Tx: Asthma and bronchospasm
AE: sympathetic overactivation
CNS: nervousness headache
CV: palpitation, tachycardia
GI: xerostomia, nausea
PNS: tremor/cramps

5

Salbutamol/Albuterol (ventolin)

B2 AG
BronchoD
Tx: Asthma + bronchospasm
AE: sympathetic overactivation
CNS: nervousness headache
CV: palpitation, tachycardia
GI: xerostomia, nausea
PNS: tremor/cramps

6

Salmeterol

B2 AG
BronchoD
For asthma
Has exosites
AE: xerostomia and non-odontogenic tooth pain

sympathetic overactivation
CNS: nervousness headache
CV: palpitation, tachycardia
GI: xerostomia, nausea
PNS: tremor/cramps

7

Formoterol

B2 AG
BronchoD
No exosite; chronic management of asthma
AE: sympathetic overactivation
CNS: nervousness headache
CV: palpitation, tachycardia
GI: xerostomia, nausea
PNS: tremor/cramps

8

Atropine

Musc ANT
BronchoD and decrease mucus

AE: mydriasis and xerostomia
Nervousness and hallucination

9

Ipratropium bromide

Musc ANT
BronchoD and decrease mucus
For asthma but not COPD
No CNS effect (Can’t cross BBB)

10

Tiotropium (Spiriva)

Musc ANT
BronchoD and decrease mucus
Tx: only for COPD
M3>M1>>M2

11

Theophylline (uniphyl)

PDE3/4 ANT
BronchoD
Tx: Asthma and COPD
BronchoD by increase cAMP + adenosine rec ANT + anti-inflammatory (decrease His, LT, PG)
Narrow therapeutic index
Phenytoin and barbiturate decreases half life
Erythromycin and oral contraceptive = increase half life

12

Fluticasone (Flovent)

Glucocorticoid
Anti-inflm
Tx: asthma and COPD
AE: osteoporosis and suppress immune system
Decrease PG = gastritis and ulcer

13

Ciclesonide

Glucocorticoid
Anti-inflm
Tx: asthma and COPD
AE: osteoporosis and suppress immune system
Decrease PG = gastritis and ulcer

14

Omalizumab

IgE ANT
Blocks histamine
Tx: Chronic management of asthma and COPD
AE: increase allergic rxn, malignancies, sinusitis, candidiasis, NO xerostomia

15

Zileuton

LT inhibitor - lipooxigenase INH

16

Montelukast

LT receptor INH
Blocks Cys-LT1 receptor
Tx: prophylaxis + chronic asthma
AE: non-odontogenic tooth pain, increase bleeding and thrombocytopenia
Metabolized by 2C9 and 2A4

17

Zafirlukast

LT receptor INH
Blocks Cys-LT1 receptor
Tx: prophylaxis + chronic asthma
AE: non-odontogenic tooth pain, increase bleeding and thrombocytopenia
Metabolized by 2C9 and 2A4

Less AE than montelukast

18

Thiazides

Na/Cl transporter ANT
Distal conv tubule
Tx: Mild/Mod HT
AE: xerostomia, thrombocytopenia, sialadenitis
Increase Ca reabsorption

19

Propranolol

Non-selective ANT - both B1/2
AE: xerostomia, thrombocyotpenia, fatigue, bronchospasm, bradycardia, male sexual dysfunction, hypoT
DI with epi in LA -> increase BP

20

Metoprolol

B1 ANT - cardioselective beta blocker
AE: xerostomia, thrombocytopenia
DI with epi in LA -> increase BP

21

Atenolol

B1 ANT - cardioselective beta blocker
AE: xerostomia, thrombocytopenia
DI with epi in LA -> increase BP

22

Prazosin (minidress)

A1 ANT
TX: HT
Sympatholytic
AE: xerostomia and orthostatic hypoT
Increase VasoD, HDL, decrease VLDL and LDL

23

Clonidine (catapress)

A2 AG
TX: HT
Sympatholytic - centrally acting
AE: xerostomia, sedation, bradycardia

24

A-methyldopa

A2 AG (Metabolite)
Tx: HT
Sympatholytic
False NT - prevents NE release

25

Reserpine

NE pump ANT
Tx: HT
Sympatholytic - indirect - prevents release
AE: depression

26

Guanethidine

NE pump ANT
Sympatholytic indirect
TX: HT
No depression

27

Nifedipine (Adalat)

Ca channel blocker
On BV SMC
TX: HT
AE: vasoD - dizziness, edema, peripheral vasoD - decrease Ca = vasoD and less CO
GINGIVAL HYPERPLASIA
Dihydropiridine - doesn’t affect AV

28

Verapamil

Ca channel blocker - L type (cardiac)
TX: HT
AE: gingival hyperplasia and reduce AV conduction and constipation
Non-DHP
Decrease chrono and iono trophy

29

Diltiazem (cardizem CD)

Ca channel blocker - L type (cardiac)
TX: HT
AE: gingival hyperplasia and reduce AV conduction and constipation
Non-DHP
Decrease chrono and iono trophy

30

Sodium nitroprusside

Increase NO - VasoD
For emerg HT only