Drugs Flashcards
(43 cards)
Which drugs work on the mesolimbic pathway?
Antipsychotics
Which pathway is involved with extrapyramidal symptoms of drugs?
Nigrostriatal
Decreased dopamine in the tuberoinfundibular pathway causes what with boobs?
Gynecomastia, lactation
What’s the first-line treatment for narcolepsy?
Modafinil
What are 4 good maintenance treatments for bipolar?
- Lithium
- Valproate
- Lamotrigine
- Quetiapine
What are the 2 main organs that lithium affects?
- Thyroid
2. Kidneys
What’s a first-line monotherapy for bipolar (for patients with frequent hospitalizations or aggression etc)?
Lithium or valproate plus second generation antipsychotic
What’s the treatment for PCP intoxication?
Benzos
Which 2 antipsychotics are less likely to cause tardive dyskinesia?
- Clozapine
2. Quetiapine
What class of drugs can treat extrapyramidal symptoms but not TD?
Anticholinergics
What 2 drugs treat acute dystonia?
- Benztropine
2. Diphenhydramine
What 3 drugs treat akathisia?
- B-blocker
- Benzodiazepine
- Benztropine
What 2 drugs treat parkinsonism?
- Benztropine
2. Amantadine
What 2 drugs treat tardive dyskinesia?
- Valbenazine
2. Deutetrabenazine
What are the 4 adverse effects of Clozapine?
- Agranulocytosis
- Seizures
- Myocarditis
- Metabolic syndrome
What are the 2 treatments for lithium toxicity?
- IV hydration
2. Hemodialysis (if severe)
What do pupils look like in opioid withdrawal?
Dilated
Which 2 types of drugs can cause seizures during withdrawal?
- Alcohol
2. Benzos
What’s the treatment for NMS after stopping the antipsychotic?
Restart dopamine agents; if refractory: Dantrolene or Bromo
What kind of a drug is levodopa?
Dopamine precursor
What kind of a drug is pramipexole?
Dopamine agonist
Can too high of a dose of carbidopa-levodopa cause psychosis?
Yep
What are 3 alternatives to amphetamines for ADHD?
- Atomoxetine
- Guanfacine
- Clonidine
What syndrome is caused by B1 deficiency, is associated with mammillary bodies, and has anterograde amnesia and confabulations?
Korsakoff syndrome
