Drugs affecting male productive system ch. 41

Question 1

What is penile erection dysfunction>

Answer 1

Condition in which the corpus cavernosum does not fill with blood to allow for erection
* Aging process
* Vascular/neuro conditions

Question 2

Describe phosphodiesterase type 5 (PDE5) inhibitors

Answer 2

Allows for smooth muscle relaxation and filling of the corpus cavernosum
* Can be timed for sexual activity based on drug onset
* Difference in the various PDE5 is in the onset and duration
* Some last approximately 4 hours (Viagra, Levitra)
* Others last approximately 36 hours (Cialis)

Question 3

what is **sildenafil (Viagra)?

Answer 3

PDE5 INHIBITORS

Question 4

what are adverse effects sildenafil (Viagra)?

Answer 4

HA, flushing, diarrhea,
ototoxicity/hearing loss

Question 5

what are contras of sildenafil (Viagra)?

Answer 5

Obstruction, penile implants, women (?)

Question 6

what are cautions of sildenafil (Viagra)?

Answer 6

Bleeding disorders, CAD, PUD, long QT

Question 7

what are drug interactions with sildenafil (Viagra)?

Answer 7

Nitrates, alpha adrenergic blockers 
serious cardiovascular events

Question 8

What are nursing considerations

Answer 8

Not to be taken with grapefruit, avoid
high fat meals prior to use
* Stress that meds are only effective in
presence of sexual stimulation