Drugs and NRTMs Flashcards

1
Q

Heroin

A
  • Normal: inhibitory NRTMs active in synapse stop domamine from being released
  • Heroin stops inhibitory NRTM from being released and dopamine is let free
  • Heroin mimics Opiate (natural)
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1
Q

Marijuana

A
  • Normal: inhibitory NRTMs active in synapse stop domamine from being released
  • cannabinoid receptors blocked by THC which turns off inhibitory NRTM so dopanie released
  • THC mimics anandamide
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2
Q

LSD

A
  • LSD enters into synapse and takes up seratonin receptors
  • LSD can excite or inhibit cell it attatches to through receptor
  • LSD mimics seratonin
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3
Q

Alcohol

A
  • Normal: GABA inhibits action potentials while GLUTAMATE excites action potentials to control neural activity
  • alcohol interacts with both GABA and GLUTAMATE receptors
  • makes GABA more inhibitory and GLUTAMATE inhibitory
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4
Q

Ecstasy

A
  • Normal: seratonin transporters remove SRTN from cleft after its done its job
  • ecstasy is taken up by transporters instead of the SRTN
  • seratonin continues to bind with receptor (overstimulation)
  • ecstasy mimics seratonin
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5
Q

Cocaine

A

Normal: dopamine transporters remove dop from cleft after job done
- cocain blocks transporters so dop trapped in cleft (overstimulation)

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6
Q

Methamphetamine

A
  • Normal: dopamine transporters remove dop from cleft after job done
  • Transporters take meth instead of dop
  • dop stuck in synapse, binds again and again, overstim
  • meth mimics dopamine
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7
Q
A
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