Drugs and the kidney Flashcards
1
Q
What are some renal scenarios when drug dose might need to be reduced?
A
GFR reduced
tubular excretion of drugs reduced
if other methods of drug excretion (eg. liver) are less than 50% - think kidney function
2
Q
What drugs can turn urine red?
A
rifampicin
phenothiazines
3
Q
What drugs can cause a false positive urine protein dip stick?
A
cephalosporins
penicillins
tolbutamide
4
Q
What drugs can cause alterations in renal blood flow?
A
NSAIDs
ACE-i + ARBs
ciclosporin
5
Q
What drugs can cause direct tubular toxicity?
A
aminoglycosides
cisplatin
amphotericin
6
Q
What drugs can cause glomerulonephritis?
A
gold
penicillamine
7
Q
Common drugs which require monitoring of U&Es?
A
ACE-i/ARBs
diuretics
DOACs
carbamazepine
lithium
digoxin
8
Q
At what eGFR should metformin be stopped?
A
<30ml/min
