drugs containing alkaloids Flashcards
(19 cards)
Based on their basic character and solubility profiles.
extraction
Nitrogenous organic molecule that has a pharmacological effect on humans and animals
alkaloids
These alkaloids can also be derived from nonamino acid precursors.
pseudoalkaloids
The alkaloids isolated from plants of these families, while having several legitimate medicinal uses, are probably best known for their toxic properties.
tropane alkaloids
Derived from an amino acid is not a part of the heterocyclic.
protoalkaloids
These are also known as heterocyclic alkaloids and contain nitrogen in heterocyclic ring system.
typical alkaloid
These are also known as nonheterocyclic alkaloids and contain nitrogen in aliphatic chain.
atypical alkaloids
Alkaloids are generally classified by their common molecular precursors, based on the biological pathway used to construct the molecule.
classification
Alkaloids have a bitter taste and appear as a white solid, except nicotine which has a brown liquid.
true alkaloids
The collected powdered material is extracted with water or aqueous alcohol containing dilute acid.
method b
A CLASS OF COMPOUNDS WHICH TYPICALLY CONTAIN NITROGEN AND HAVE COMLEX RING STRUCTURES
alkaloids
_________ WAS THE SCOURGE OF EUROPE, LIKELY HAVING INTRODUCES THROUGH THE MIDDLE EAST. IT IS CAUSED BY PROTOZOA OF THE GENUS Plasmodium.
malaria
ARE COMMONLY FOUND IN PLANTS OF THREE FAMILIES, SOLANACEAE, ERYTHROXYLACEAE, AND CONVOLVULACEAE FAMILIES.
tropane alkaloids
HE IS AN FRENCH APOTHECARY THAT ISOLATED THE ALKALOID AFTERWARDS KNOWN AS NARCOTINE IN 1803
CHARLES DEROSNE
HE IS AN HANOVERIAN APOTHECARY THAT FURTHER INVESTIGATED OPIUM AND ISOLATED MORPHINE
FRIEDRICH SERTURNER
OBTAINED FROM AMINO ACID AND THEY SHARE A HETEROCYCLIC RING WITH NITROGEN. THEY ARE HIGHLY REACTIVE SUBSTANCES WITH BIOLOGICAL ACTIVITY EVEN IN LOW DOSES.
TRUE ALKALOIDS
THEY ARE DERIVED FROM THE PRECURSORS OR POST-CURSORS OF AMINO ACID THAT ALSO RESULT FROM THE AMINATION AND TRANSAMINATION REACTIONS OF THE DIFFERENT PATHWAYS.
PSEDOALKALOIDS
THESE ARE ALSO KNOWN AS NONHETEROCYCLIC ALKALOIDS AND CONTAIN NITROGEN IN ALIPHATIC CHAIN.
ATYPICAL ALKALOIDS
THESE ARE ALSO KNOWN AS HETEROCYCLIC ALKALOIDS AND CONTAIN NITROGEN IN HETEROCYCLIC RING SYSTEM.
TYPICAL ALKALOIDS
