Drugs, drugs, drugs

Question 1

imipramine, nortriptyline, clomipramine, amitriptyline are in what drug class?

Answer 1

TCA’s

Question 2

TCA MOA

Answer 2

inhibits reuptake of NE and serotonin

Question 3

what is lithium used for? What is it’s therapeutic index?

Answer 3

acute mania (bipolar); very LOW index

Question 4

what is dangerous about a TCA overdose?

Answer 4

life-threatening arrhythmias; it can also lower seizure threshold

Question 5

What disorder would not be indicated for treatment with TCA’s?

Answer 5

bipolar

Question 6

valproic acid, divalproex sodium, carbamazepine are in what drug class?

Answer 6

anticonvulsants

Question 7

What taste does lithium leave in the mouth?

Answer 7

metallic taste is normal

Question 8

What are some adverse effects of anticonvulsants?

Answer 8

somnolence, headache, GI upset, weight gain

Question 9

AE of lithium

Answer 9

headache, dry mouth, polydipsia, GI upset, fine tremor

Question 10

fluoxetine, paroxetine, sertraline, citalopram, escitalopram are in what drug class?

Answer 10

SSRI’s

Question 11

What medication shouldn’t you take with SSRI’s?

Answer 11

MOAI’s

Question 12

SSRI’s take a minimum of how many weeks to work?

Answer 12

2 weeks at least

Question 13

This SSRI is good for anorexia

Answer 13

fluoxetine

Question 14

venlafaxine, desvenlafaxine, duloxetine are in what drug class?

Answer 14

SNRI

Question 15

What food is contraindicated in MAOI’s?

Answer 15

tyramine

Question 16

phenelzine, tranylcypromine are in what drug class?

Answer 16

MAOI

Question 17

bupropion is indicated for what? And is contraindicated for what?

Answer 17

indicated: smoking cessation, depression
contraindicated: bulimia

Question 18

when would you use mirtazapine? AE?

Answer 18

a depressed patient who can’t sleep;

AE: weight gain and increased appetite

Question 19

Would patient has not responded to their SSRI and it’s been six (to eight) weeks- what do you do?

Answer 19

1. start a different SSRI
   OR
2. at bupropion

Question 20

second line augment tx

Answer 20

lithium or thyroid

Question 21

Third line treatment for depression?

Answer 21

mirtazapine or nortriptyline

Question 22

4th line depression treatment

Answer 22

MAOI

Question 23

define remission

Answer 23

three weeks without symptoms

Question 24

what are the atypical antipsychotics?

Answer 24

risperidone and olanzapine

Question 25

These extrapyramidal symptoms develop first when taking antipsychotics

Answer 25

dystonias