Drugs For Diabetes Flashcards

(33 cards)

1
Q

Pre diabetic conditions

A

Sugar level in fasting is 100-125 and random level below 200

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2
Q

Type 1 diabetes

A

Destruction of beta cells of pancreas

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3
Q

Type 2

A

Insulin resistance

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4
Q

Diabetes symptoms

A

Polydepsia
Polyurea
Poly phagia
Dry mouth fatigue
Ketoacidosis

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5
Q

4 drugs used for diabetes

A

GYMNEMA
SYZYGIUM
AZADIRACHTA
MOMORDICA

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6
Q

GYMNEMA sn

A

GYMNEMA Sylvestre

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7
Q

GYMNEMA local name

A

Asclepiadaeae

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8
Q

GYMNEMA ln.

A

Gurmar

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9
Q

GYMNEMA cons.

A

Gymnemic acid
Gymnemoside
Gymnemo saponins
Tannins and mucilins…

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10
Q

Moa of GYMNEMA

A

Increase insulin secretion from pancreas
Inhibition of hormones that increases glucose form liver…

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11
Q

ADRs of GYMNEMA

A

There may be some hypoglycemia

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12
Q

Uses of GYMNEMA

A

Diabetes
Hepatic disorders
Gastric disorders

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13
Q

SYZYGIUM SN

A

SYZYGIUM Jambolanum

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14
Q

SYZYGIUM LN

A

Jamun

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15
Q

SYZYGIUM fam.

A

Myrtaceae

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16
Q

SYZYGIUM con.

A

Jamboline, Vit B. Vit C glycosides, kaemferol..

17
Q

Jamboline glycosides MOA

A

Increase insulin secretion
Block reductase enzyme

18
Q

Alkaloid jambocine and glycosides gamboline MOAs

A

Inhibition of starch conversion to sugar

19
Q

Uses of SYZYGIUM

A

Diabetes
Diarrhea
Gastric problems
Bronchitis

20
Q

AZADIRACHTA SN

A

Melia AZADIRACHTA

21
Q

LN of AZADIRACHTA

22
Q

AZADIRACHTA class

23
Q

AZADIRACHTA cons.

A

Azadirachtine…

24
Q

MOA of AZADIRACHTA

A

Regeneration of beta cells
Decrease in glycosidic activity
Inhibition of serotonin effect on insulin

25
ADRs.
Maybe the loss of fertility in men Severe reaction in children Vomiting, diarrhea , loss of consciousness and even death
26
Uses of AZADIRACHTA
Use in diabetes Sedative and anthalmentic..
27
MOMORDICA
MOMORDICA charantia
28
Local name of MOMORDICA
Karela
29
MOMORDICA family
Cucurbitaceae
30
Constituents of MOMORDICA
Charantin, Cucurbitacin B- carotene Lectin...
31
MOA of MOMORDICA Role of charantin and lectin
Charantin increases insulin sensitivity Lectin has insulin like activity
32
Uses of MOMORDICA
Antidiabetic Stomachic Gout Ulcer Anthelmintic
33
ADRs of MOMORDICA
Diarrhea Hypoglycemia Fever