Drugs For Diabetes Flashcards
(33 cards)
Pre diabetic conditions
Sugar level in fasting is 100-125 and random level below 200
Type 1 diabetes
Destruction of beta cells of pancreas
Type 2
Insulin resistance
Diabetes symptoms
Polydepsia
Polyurea
Poly phagia
Dry mouth fatigue
Ketoacidosis
4 drugs used for diabetes
GYMNEMA
SYZYGIUM
AZADIRACHTA
MOMORDICA
GYMNEMA sn
GYMNEMA Sylvestre
GYMNEMA local name
Asclepiadaeae
GYMNEMA ln.
Gurmar
GYMNEMA cons.
Gymnemic acid
Gymnemoside
Gymnemo saponins
Tannins and mucilins…
Moa of GYMNEMA
Increase insulin secretion from pancreas
Inhibition of hormones that increases glucose form liver…
ADRs of GYMNEMA
There may be some hypoglycemia
Uses of GYMNEMA
Diabetes
Hepatic disorders
Gastric disorders
SYZYGIUM SN
SYZYGIUM Jambolanum
SYZYGIUM LN
Jamun
SYZYGIUM fam.
Myrtaceae
SYZYGIUM con.
Jamboline, Vit B. Vit C glycosides, kaemferol..
Jamboline glycosides MOA
Increase insulin secretion
Block reductase enzyme
Alkaloid jambocine and glycosides gamboline MOAs
Inhibition of starch conversion to sugar
Uses of SYZYGIUM
Diabetes
Diarrhea
Gastric problems
Bronchitis
AZADIRACHTA SN
Melia AZADIRACHTA
LN of AZADIRACHTA
Neem
AZADIRACHTA class
Meliaceae
AZADIRACHTA cons.
Azadirachtine…
MOA of AZADIRACHTA
Regeneration of beta cells
Decrease in glycosidic activity
Inhibition of serotonin effect on insulin