Drugs for Rheumatoid Arthritis Flashcards
(6 cards)
1
Q
class and effect of methotrexate?
A
- DMARD
- anti-inflammatory and immunosuppressive
2
Q
How is hydroxychloroquine anti inflammatory?
A
inhibits synthesis of inflammatory cytokines:
- TNF alpha
- IL1B
- Gamma interferon
3
Q
class and effect of hydroxychloroquine?
A
- DMARD
- anti-inflammatory
- can relieve pain when given with methotrexate
4
Q
what class of drug is filgotinib?
A
JAK inhibitor
5
Q
how does filgotinib work?
A
inhibits JAK proteins which play an important role in signal transduction for pro inflammatory cytokines
6
Q
recommended dosages for filgotinib, methotrexate and hydroxychloroquine?
A
filgotinib - 200mg daily
methotrexate - 7.5-25mg injections weekly
hydroxychloroquine - 200-400mg daily
