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Baloney > Drugs - Gynecology / Urology > Flashcards

Drugs - Gynecology / Urology Flashcards

1
Q

Hormones

A 
DHEA
Estradiol
Estriol
Conjugated estrogens / Premarin
Estrone
Pregnenolone
Progesterone
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2
Q

DHEA class and indications?

A

Anabolic steroid

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3
Q

DHEA interactions, contraindications, cautions, adverse effects?

A

2

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4
Q

Estradiol / Estriol class and indications?

A

Estradiol - Hormone – modulates pituitary secretion of gonadotropins, LH and FSH thru negative feedback

Vulvar atrophy, vaginal atrophy in menopause - - metastatic breast cancer - - hypoestrogenism - - osteoporosis - - prostate cancer

Estriol - Hormone – normalizes vaginal epithelium - - mild proliferative effect on endometrium

Menopausal hormone replacement therapy - - infertility due to cervical hostility - - menopausal atrophic vaginitis

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5
Q

Estradiol / Estriol interactions, contraindications, cautions, adverse effects?

A

2

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6
Q

Estrone class and indications?

A

Menopausal HRT - - Osteoporosos prophylaxis

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7
Q

Estrone interactions, contraindications, cautions, adverse effects?

A

2

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8
Q

Pregnenolone class and indications?

A

Precursor of steroid hormone

Memory enhancement

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9
Q

Pregnenolone interactions, contraindications, cautions, adverse effects?

A

2

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10
Q

Progesterone class and indications?

A

Amenorrhea - - Abnormal uterine bleeding - - Contraception - - PMS. Induces secretory change in endometrium, promotes mammary gland development, relaxes uterus, blocks follicular maturation and and ovulation, and maintains pregnancy.

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11
Q

Progesterone interactions, contraindications, cautions, adverse effects?

A

2

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12
Q

Contraceptives

A

Levonoregestrel
IUD
Medroxy-progesterone
Norgestimate

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13
Q

Levonoregestrel IUD class and indications?

A

Synthetic progestin

Contraception - - Menorrhagia - - Endometriosis - - Anemia. Synthetic progestin, inhibits ovulation by negative feedback on hypothalamus → reduced secretion FSH, LH

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14
Q

Levonoregetrel IUD interactions, contraindications, cautions, adverse effects?

A

2

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15
Q

Medroxyprogesterone class and indications?

A

Progesterone - Depo-provera

Contraception - - Endometriosis. Synthetic progesterone - - converts proliferative phase of endometrium into secretory phase – has no estrogenic effects, some androgenic & anabolic activities.

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16
Q

Medroxyprogesterone interactions, contraindications, cautions, adverse effects?

A

2

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17
Q

Norgestimate class and indications?

A

Mononessa

Contraception. Progestin + estrogen – inhibits gonadotropin secretion from pituitary – prevents follicular maturation and ovulation - - stimulates growth of mammary tissues.

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18
Q

Norgestimate interactions, contraindications, cautions, adverse effects?

A

2

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19
Q

Labor Induction

A

Oxytocin

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20
Q

Oxytocin class and indications?

A

Posterior pituitary hormone

Post-partum hemorrhage - - Labor induction - - Incomplete or inevitable abortion

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21
Q

Oxytocin interactions, contraindications, cautions, adverse effects?

A

2

22
Q

BPH drugs

A

Finasteride

Tamsulosin

23
Q

Finasteride class and indications?

A

5-alpha reductase inhibitor

BPH - - Male pattern baldness (alopecia)

24
Q

Finasteride interactions, contraindications, cautions, adverse effects?

A

2

25
Q

Tamsulosin class and indications?

A

BPH - - Hepatic impairment - - Renal impairment - - Ureter stone expulsion

26
Q

Tamsulosin interactions, contraindications, cautions, adverse effects?

A

2

27
Q

Erectile Dysfunction

A

Sildenafil

28
Q

Sildenafil class and indications?

A

Phosphodiesterase 5 inhibitor

Erectile dysfunction

29
Q

Sildenafil interactions, contraindications, cautions, adverse effects?

A

2

30
Q

Urinary Tract Infections / Prostatitis

A

Phenazopyridine
Nitrofurantoin
Ciprofloxacin
Amoxicillin

31
Q

Urinary Tract Antiseptic

A

Phenazopyridine

32
Q

Phenazopyridine class and indications?

A

Non-opioid urinary analgesic / antiseptic

Cystitis, Prostatitis, Urethritis pain and irritability

33
Q

Phenazopyridine interactions, contraindications, cautions, adverse effects?

A

2

34
Q

UTI / STI Antibiotics

A 
Phenazopyridine
Nitrofurantoin
Ciprofloxacin
Amoxicillin
Azithromycin
Doxycycline
Metronidazole
Fluconazole
35
Q

Nitrofurantoin class and indications?

A

Macrobid - - 5-nitrofuran derivative

Kills E. coli in UTI
Urinary Tract Infections – acute, uncomplicated UTIs. Interferes w/ cell metabolism and cell wall synthesis. Bactericidal to most gram (+) and gram (-) urinary pathogens.

36
Q

Nitrofurantoin interactions, contraindications, cautions, adverse effects?

A

2

37
Q

Ciprofloxacin class and indications?

A

Fluoroquinolone → Broad spectrum nucleic acid inhibitor that prevents DNA unwinding

X FOR ANTHRAX
Diverticulitis - - Urinary tract - - Prostate - - Intra-abdominal (w/ Metronidazole)
Bone or joint and skin infections - - Inhalational anthrax - - Infectious diarrhea - - Otitis media - - Chronic sinusitis - - Chlamydia - - Gonorrhea
Cipro is broad spectrum abx prescribed during lag time waiting for culture and sensitivity - - when results are in, prescribe specific abx

38
Q

Ciprofloxacin interactions, contraindications, cautions, adverse effects?

A

2

39
Q

Amoxicillin class and indications?

A

Beta-Lactam – Bactericidal → inhibits cell wall synthesis
Broad spectrum penicillin

Strep throat - - Sinusitis - - Pneumonia - - UTI - - Chlamydia
Ear, Nose, Throat infxn - - Genitourinary tract - - Skin structure - - Gonorrhea
Lower Resp Tract w/ susceptible beta-lactamase negative strains of Streptococcus spp (a and b-hemolytic strains only). Acute, uncomplicated gonorrhea (ano-genital and urethral infxn) d/t Neisseria gonorrhea in both M+F

40
Q

Amoxicillin interactions, contraindications, cautions, adverse effects?

A

2

41
Q

Azithromycin class and indications?

A

Macrolide antibiotic – protein synthesis inhibitor

Diarrhea, Legionella (Legionnaire’s Dz aka Atypical Pneumonia) - - Chlamydia urethritis - - Chancroid
URTI (Otitis media, Sinusitis) d/t Streptococci, Pneumococci, H. influenzae - - Mycobacterium avium

42
Q

Azithromycin interactions, contraindications, cautions, adverse effects?

A

2

43
Q

Doxycycline class and indications?

A

Tetracycline antibiotic – broad spectrum bacteriostatic protein synthesis inhibitor. Penicillin alternative

Acne - - Lyme Disease (Borrelia bergdorferi infxn) - - Mycoplasma pneumonia - - Chlamydia
Gonorrhea and Syphilis if Penicillin allergy - - Cholera - - Rickettsia (ie Typhus, no relation to Rickets)

44
Q

Doxycycline interactions, contraindications, cautions, adverse effects?

A

2

45
Q

Metronidazole class and indications?

A

Antiparasitic, Antibiotic

C. difficile treatment - - Diverticulitis
Amoebiasis - - Balantidiasis - - Trichomoniasis
Giardiasis - - Bacterial vaginosis - - H. pylori - - Rosacea - - Tetanus

46
Q

Metronidazole interactions, contraindications, cautions, adverse effects?

A

2

47
Q

Fluconazole class and indications?

A

Systemic antifungal - - Synthetic azole - - Inhibits fungal cell membrane formation → Kills

Yeast infections
Candidiasis → Oropharyngeal (Thrush), Esophageal, Systemic - - Candida UTI - - Candidal balanitis
Bone marrow transplant prophylaxis
Cryptococcal meningitis

48
Q

Fluconazole interactions, contraindications, cautions, adverse effects?

A

2

49
Q

Urinary Antispasmodic

A

Tolterodine

50
Q

Tolterodine class and indications?

A

Anticholinergic
Urinary antispasmodic

Overactive bladder - - Urge urinary incontinence - - Urinary urgency and frequency
Competitive muscarinic receptor antagonist – similar to atropine – relaxes smooth mm

51
Q

Tolterodine interactions, contraindications, cautions, adverse effects?

A

2

Baloney (37 decks)

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