Drugs In Heart Failure

Question 1

5 core drugs in heart failure

Answer 1

Diuretics
B blockers
Vasodilators
ACEIs
Inotropes

Question 2

Cardiac glycoside that inhibits Na/K ATPase and increase intracellular Ca++ resulting to an increase cardiac contractility

Answer 2

Digoxin

Question 3

Drugs that causes competitive inhibition to Digoxin

Answer 3

Quinidine
Amiodarone
Cyclosporine
Diltiazem
Verapamil

Queen Amidala Castrated Darth Vader

Question 4

What arrhythmia is caused by Digoxin

Answer 4

Premature ventricular arrhythmia

Question 5

Anti-arrhythmic drug of choice for Digitalis Toxicity

Answer 5

Lidocaine

Alt: Phenytoin

Question 6

Digoxin antibodies

Answer 6

Digibind

Fab fragments

Question 7

Drugs that improves survival in cases of Heart failure

Answer 7

ACEIs
B blockers
Aldosterone antagonists

ABA buhay ka pa pala

Question 8

Polymorphic ventricular tachycardia caused by antiarrhythmitics that changes the shape of the action potential and prolong QT interval

Answer 8

Torsades de Pointes

Question 9

Drug of choice for Torsades de Pointes

Answer 9

Magnesium Sulfate

Question 10

Class 1 anti-arrhythmics that causes prolongation of AP duration

Answer 10

Group 1A

Question 11

Class 1 anti-arrhythmics that causes shortening of AP duration

Answer 11

Class 1B

Question 12

MoA of class 1A anti-arrhythmics

Answer 12

Slows down conduction velocity and pacemaker activity thereby causing prolongation of AP

Question 13

Class 1a anti-arrhythmic drugs

Answer 13

Quinidine
Procainamide
Disopyramide

QPD loves to prolong heart actions

Question 14

Triad of cinchonism

Answer 14

Headache
Tinnitus
Vertigo

Question 15

Drug pf choice for drug induced arrhythmias

Answer 15

Sodium lactate