Drugs in Pregnancy

Question 1

Which can cause in the end of pregnancy?

Answer 1

resulting pulmonary hypertension

Question 2

Aspirin which can cause in end of pregnancy?

Answer 2

haemorrhage in neonate

Question 3

Phenytoin in stage 2?

Answer 3

Hydantoin syndrome

Question 4

Valproic acid ?

Answer 4

neural tube defects

Question 5

Diethyl stilbestrol ?

Answer 5

vaginal adenocarcinoma after puberty in
females and hypotrophic testis in male fetus.

Question 6

FDA Risk categories?

Answer 6

● A…Remote risk of fetal harm
● B…No risk in animal studies , no well controlled human studies
● C…Risk in animal studies, no well controlled human studies
● D… Proven risk of fetal harm -potential benefits versus risk
● X…Proven risk of fetal harm - Drugs should not be used.

Question 7

Prescribing in pregnancy?

Answer 7

Use the smallest effective dose
 Use tried and tested drugs wherever possible in preference to new agents
 Minimize prescribing
 Warn the pregnant women about the risks of Smoking, Alcohol, OTC over the
counter drugs and drugs of abuse
 Keep Naloxone available in case of administering opioids to mother to treat
neonatal respiratory depression