Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Baloney > Drugs - Neurology > Flashcards

Drugs - Neurology Flashcards

1
Q

Anticholinergics

A

Atropine

Tolterodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Atropine class and indications?

A

Anticholinergic (antimuscarinic)
Anti-arrhythmic

Bradycardia - - Organophosphate poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Atropine interactions, contraindications, cautions, adverse effects?

A

A/E: Dry mouth, tachycardia, palpitations, arrhythmias, mydriasis, photophobia, raised intraocular pressure.

Toxicity: Tachycardia, hyperpyrexia, restlessness, confusion, excitement, hallucination, delirium, may progress to circulatory failure + respiratory depression

INT: Quinidine, anti-depressants, some antihistamines -> additive anticholinergic effects

CI: Narrow angle glaucoma, Myesthenia gravis, Ulcerative colitis, Toxic megacolon, Acute hemorrhage w/ cardiovascular instability, Thyrotoxicosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tolterodine class and indications?

A

Anticholinergic
Urinary antispasmodic

Overactive bladder - - Urge urinary incontinence - - Urinary urgency and frequency
Competitive muscarinic receptor antagonist – similar to atropine – relaxes smooth mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tolterodine interactions, contraindications, cautions, adverse effects?

A

A/E: Dry mouth, chest pain, headache, somnolence, fatigue, dry skin, abdominal pain, constipation, dyspepsia, diarrhea, dizziness, anxiety, weight gain, abnormal vision, dry eyes, paresthesia, nervousness, urinary retention

INT: Macrolide abx, antifungals, vinblastine, cyclosporine -> Risk of overdose
Rivastigmine, Donepezil -> risk of cholinergic neurogenic hypersensitivity

CI: Urinary retention - - gastric retention
Pregnancy, BPH, Narrow angle glaucoma, Myesthenia gravis, Ulcerative colitis, Toxic megacolon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Sympathomimetics

A 
Dextroamphetamine
Methylphenidate
Oxymetazoline
Pseudoepinephrine
Phenylephrine
Phentermine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dextroamphetamine class and indications?

A

Amphetamine – CNS Stimulant
Narcolepsy - - ADHD.
Amphetamines = non-catecholamine sympathomimetic amines.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dextroamphetamine interactions, contraindications, cautions, adverse effects?

A

A/E: Appetite loss, insomnia, abdominal pain, palpitations, tachycardia, elevated BP, loss of libido

INT: Amphetamines, Tricyclics, MAOI, Norepinpehrine -> increase absorption of these

CI: Hyperthyroidism, glaucoma, hypertension, advanced arteriosclerosis, MAOI, agitated states

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Methylphenidate class and indications?

A

SNRI - Piperidine derivative

ADHD - - Narcolepsy.
Increases release of norepinephrine → stimulates impulse transmission in respiratory system & CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Methylphenidate interactions, contraindications, cautions, adverse effects?

A

A/E: Decreased appetite, insomnia, headache, abdominal pain, nausea, vomiting

INT: Blood pressure medications may be less effective
Phenytoin and TCAs may have serum levels raised

CI: Within 2 weeks of MAOI - Heart issues - Glaucoma - Marked anxiety, tension, agitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Oxymetazoline class and indications?

A

Decongestant (Vicks)
Sinusitis - Congestion - - nasal spray or drops to relieve congestion
Vasoconstrictor effect on mucosal blood vessels topically → reduces edema of nasal mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Oxymetazoline interactions, contraindications, cautions, adverse effects?

A

A/E: Rebound congestion w/ prolonged use
Nasal spray -> stinging, burning, dry mouth/throat
Headache, insomnia, tachycardia, HTN, nervousness, nausea, dizziness, palpitation, arrhythmia

INT: None

CI: Glaucoma, hyperthyroidism, heart dz, hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pseudoephedrine class and indications?

A

Decongestant
Alpha and Beta adrenergic receptor agonist

Nasal congestion

Alpha-adrenergic receptor agonist → vasoconstriction by simulation of receptors of resp mucosa
Beta-adrenergic receptor agonist → bronchial relaxation, increased heart rate and contractility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pseudoephedrine interactions, contraindications, cautions, adverse effects?

A

A/E: Rebound congestion and rhinorrhea, nervous issues, mood changes, confusion, hypotension, faint, flushing, heartrate changes, arrhythmias, Anginal pain

INT: MAOI co-admin -> Hypertensive crisis
Digoxin, Quinidine, TCA -> HTN, Arrhythmias risk

CI: Pheochromocytoma, Severe hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Phenylephrine class and indications?

A

Decongestant - - Alpha (and weak Beta) adrenergic agonist

Nasal congestion spray - - Mydriasis eye dropper

Vasoconstriction of arterioles of nasal mucosa d/t alpha adrenergic receptor agonist stimulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Phenylephrine interactions, contraindications, cautions, adverse effects?

A

A/E: Mood changes, nervous issues, confusion, heartrate changes, increased salivation, SOB

INT: Beta Blockers may have increased hypotensive fx
MAOI co-admin -> potentiates HTN

CI: Hypertension - V-tach - Angle Closure Glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Phentermine class and indications?

A

Sympathomimetic appetite suppressant

Obesity – short term use for moderate to severe obesity
Stimulates cerebral cortex → suppresses appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Phentermine interactions, contraindications, cautions, adverse effects?

A

A/E: Urticaria, heartrate changes, nervous issues, dry mouth, change in libido / impotence

INT: Antacids - TCA (risk of arrhythmia) - Phenytoin, Phenobarbital serum concentrations reduced

CI: Pulmonary HTN, Hypertension, CVD, Glaucoma, within 2 weeks of MAOI, Lactation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Cholinergic agonist

A

Nicotine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Nicotine class and indications?

A

Cholinergic agonist

Smoking cessation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Nicotine interactions, contraindications, cautions, adverse effects?

A

A/E: PATCH -> Skin rash - discontinue if severe, vasculitis - - Gum etc -> headache, nervous sx, dysmenorrhea, cold and flu, chest pain

INT: Nicotine patch + Bupropion = hypertension

CI: Recent stroke, acute MI, unstable angina, severe arrhythmias, occasional smokers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Acetylcholinesterase inhibitors

A

Donepezil

Rivastigmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Donepezil class and indications?

A

Cholinesterase inhibitor
Alzheimer’s Dz (mild to moderate)
Inhibits cholinesterase in CNS - - increase acetylcholine transmission - - slows cognitive decline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Donepezil interactions, contraindications, cautions, adverse effects?

A

Same as Rivastigmine

A/E: M/C HA, Diarrhea, Nausea

GI sx -> Diarrhea, nausea, vomiting, increased acid - - bradycardia, vivid dreams causing insomnia

INT: Increases cholinergic effects, decreases anticholinergic effects

CI: RELATIVE CIs -> HR changes, Ht dz, asthma, copd, ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Rivastigmine class and indications?

A

Cholinesterase inhibitor
Alzheimer’s Dz (mild to moderate)
Inhibits cholinesterase in CNS - - increase acetylcholine transmission - - slows cognitive decline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Rivastigmine interactions, contraindications, cautions, adverse effects?

A

Same as Donepezil

A/E: GI sx -> Diarrhea, nausea, vomiting, increased acid - - bradycardia, vivid dreams causing insomnia

INT: Increases cholinergic effects, decreases anticholinergic effects

CI: RELATIVE CIs -> HR changes, Ht dz, asthma, copd, ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Benzodiazepines

A

Alprazolam

Diazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Alprazolam class and indications?

A

Xanax
Benzodiazepine anxiolytic

Anxiety – short term management - - Anxiolytic, muscle-relaxant, anticonvulsant, anti-depressant, sleep modifying effects. Binds to GABA specific sites throughout CNS → increases inhibitory effect of GABA on neuronal excitability (ie decreases neuronal excitability)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Alprazolam interactions, contraindications, cautions, adverse effects?

A

A/E: Drowsiness m/c - - also depression, HA, dry mouth, confusion, vertigo

INT: Potentiates alcohol and CNS depressants

CI: Pregnancy, lactation - Angle closure glaucoma - severe hepatic impairment - sleep apnea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Diazepam class and indications?

A

Valium
Benzodiazepine anxiolytic, anticonvulsant

Severe anxiety - - Insomnia w/ anxiety - - MM spasms - - Alcohol withdrawal sx - - Seizures - - RLS Anxiolytic, muscle-relaxant, anticonvulsant, anti-depressant, sleep modifying effects. Binds to GABA specific sites throughout CNS → increases inhibitory effect of GABA on neuronal excitability (ie decreases neuronal excitability)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Diazepam interactions, contraindications, cautions, adverse effects?

A

A/E: Dependence, withdrawal - Drowsiness - fatigue - confusion

INT: Increased clearance of Diazepam w/ anticonvulsants - may decrease Levodopa effectiveness - Hypothermia with Lithium - additive w/ alcohol or other CND depressant

CI: Pregnancy and lactation (D) - Myasthenia gravis - respiratory depression - hepatic impairment - angle closure glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Non benzodiazepine anxiolytics

A

Buspirone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Buspirone class and indications?

A

Non-benzodiazepine Anxiolytic

GAD Anxiety – short term management
No affinity for GABA receptors - - anxiolytic d/t affinity for serotonin receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Buspirone interactions, contraindications, cautions, adverse effects?

A

A/E: Dizziness, drowsiness, nausea, headache

INT: Alcohol/CNS depressants - MAOI combined leads to hypertension

CI: Epilepsy - hepatic or renal impairment - children under 18 - MAOI use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Insomnia

A

Zolpidem

Melatonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Zolpidem class and indications?

A

Ambien
Non-barbiturate hypnotic

Insomnia – short term management - - Strong sedative, weak anxiolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Zolpidem interactions, contraindications, cautions, adverse effects?

A

A/E: Tolerance, dependence, rebound insomnia - confusion - abnormal thought/behavior

INT: TCA -> sedation and incoordination - - Alcohol -> sedation

CI: Severe hepatic insufficiency - Elderly - Driving - GERD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Melatonin class and indications?

A

Tryptamines

Insomnia – disturbed biorhythms, sleep disorders
Cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Melatonin interactions, contraindications, cautions, adverse effects?

A

A/E: Increased seizure activity - drowsiness - headache - disruption of circadian rhythm - may worsen depression

INT: None

CI: Immunosuppressive tx concurrently

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Seizure drugs

A

Carbamazepine
Phenytoin
Gabapentin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Carbamazepine class and indications?

A

Anticonvulsant

CBZ → Cranial nerve (Trigeminal) neuralgia + Bipolar Disorder Prophylaxis + Zeizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Carbamazepine interactions, contraindications, cautions, adverse effects?

A

A/E: Ataxia (lack of voluntary coordination of mm movements) - dizziness, drowsiness, dry mouth

MAY CAUSE: Lupus - SIADH

DEPLETIONS: Folate - Vitamin D + K

INT: Decreases effect of OCP - reduces tolerance to alcohol

CI: Pregnancy (D) (causes NTD) - Porphyria - Bone marrow depression - Jaundice - Hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Phenytoin class and indications?

A

Anticonvulsant

Epilepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Phenytoin interactions, contraindications, cautions, adverse effects?

A

A/E: Hirsutism - Acne - Osteomalacia - GI problems - Dizziness, insomnia, nervous sx

INT: Enhances lithium toxic effects
Decr. serum levels/effects -> acyclovir, antineoplastics, benzodiazepines, ciprofloxacin, CYP2C9 inducers (Carbamzepine), CYP2C19 inducers (Rifampin), folic acid
Incr. metabolism of antiarrhythmics, anticonvulsants, antipsychotics, beta blockers, CCB, Chloramphenicol, Corticosteroids, Doxycycline, Estrogens, HMG CoA reductast inhibitors, Methadone, Theophylline, TCA’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Gabapentin class and indications?

A

GABAnergic Anticonvulsant

Epilepsy - - Neuropathic Pain - - Peripheral edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Gabapentin interactions, contraindications, cautions, adverse effects?

A

A/E: Ataxia - Tremor - Sedation

INT: Absorption reduced w/ antacids

CI: Lactation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Gabanergic drugs

A

Gabapentin (similar structure GABA but not agonist or antagonist - MOA not known)
Pregabalin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Pregabalin class and indications?

A

GABAnergic anticonvulsant
CNS Depressant

Fibromyalgia - - Neuropathic pain → Diabetic Neuropathy - - Shingles (post-herpetic neuralgia)
NOT Trigeminal neuralgia - - NOT acute pain - - NOT post-surgical pain
Epilepsy → Partial seizures w/ or w/out secondary generalization
Off-label → RLS, Migraine prevention, Social Anxiety, alcohol withdrawal

49
Q

Pregabalin interactions, contraindications, cautions, adverse effects?

A

A/E - Drowsiness - Ataxia - Fatigue

CI: Pregnancy (C)

50
Q

Modafinil class and indications?

A

Non-amphetamine CNS stimulant
Narcolepsy w/ Excessive daytime sleepiness (EDS)
Sleep Apnea

51
Q

Modafinil interactions, contraindications, cautions, adverse effects?

A

A/E: Back pain - Insomnia

CI: Cirrhosis - Cardiac conditions

52
Q

Skeletal muscle relaxants

A

Carisoprodol
Ketamine
Cyclobenzaprine

53
Q

Carisoprodol class and indications?

A

Skeletal muscle relaxant - Carbamate derivative

Painful muscles spasm w/ MSK conditions

54
Q

Carisoprodol interactions, contraindications, cautions, adverse effects?

A

A/E: Dizziness - Drowsiness

INT: Additive CNS depressant

CI: Lactation - Hypersensitivity - Acute Intermittent Porphyria

55
Q

Ketamine class and indications?

A

Skeletal muscle relaxant - NMDA receptor antagonist

Anesthesia

56
Q

Ketamine interactions, contraindications, cautions, adverse effects?

A

A/E: Hallucinations - Hypertension

57
Q

Cyclobenzaprine class and indications?

A

Skeletal muscle relaxant - ANS agent

Painful muscle spasm w/ MSK conditions

58
Q

Cyclobenzaprine interactions, contraindications, cautions, adverse effects?

A

A/E: Drowsy, Dizzy, Dry Mouth

INT: Alcohol - TCA - MAOI

CI: Recent MI, arrhythmias, severe liver dz

59
Q

Parkinsons

A

Levodopa-carbidopa
Pramipexole
Bromocriptine

60
Q

Levodopa-carbidopa class and indications?

A

Dopamine precursor / decarboxylase inhibitor
Monotherapy in Parkinson’s dz
Levodopa → converted to dopamine in CNS - - Carbidopa → inhibits peripheral degradation of levodopa and increases availability to CNS

61
Q

Levodopa-carbidopa interactions, contraindications, cautions, adverse effects?

A

A/E: Dizzy, Dry mouth - Confusion - Insomnia - Hallucinations

Recommend no drug holidays

CI: Lactation - Angle Closure Glaucoma - Acute MI - MAOI concurrent use

62
Q

Pramipexole class and indications?

A

Dopamine agonist
Non-ergot derivative

Parkinson’s Dz - - Restless Leg Syndrome (RLS)
Non-ergot derivative dopamine receptor agonist used as adjunct to Levodopa to manage sx in advanced Parkinson’s - - also monotherapy for initial symptomatic management in Parkinson’s

63
Q

Pramipexole interactions, contraindications, cautions, adverse effects?

A

A/E: Compulsive behavior (Gambling, Hypersexuality) - Orthostatic HTN - Somnolence - Confusion - Also headache, aches, pains, N + V, decreased appetite

CI: Lactation - shuts down lactation

64
Q

Bromocriptine class and indications?

A

Dopamine agonist
Ergot derivative

Parkinson’s Dz - - Hyperprolactinemia - - Galactorrhea - - Infertility - - Neuroleptic malignant syndrom
Ergot derived dopamine agonist – also inhibits secretion of prolactin from anterior pituitary
Must be tapered - - no drug holiday

65
Q

Bromicriptine interactions, contraindications, cautions, adverse effects?

A

A/E: Erythromyalgia (burning, redness of extremities)

Can cause Neuroleptic Malignant Syndrome - Symptoms include high fever, sweating, unstable blood pressure, stupor, muscular rigidity, and autonomic dysfunction.

Caution - Must be tapered - - no drug holiday

66
Q

Antipsychotics

A

Risperidone
Prochlorperazine
Aripiprazole
Haloperidol

67
Q

Risperidone class and indications?

A

Atypical antipsychotic
Serotonin + Dopamine Antagonist

Schizophrenia - - Psychotic disorders

68
Q

Risperidone interactions, contraindications, cautions, adverse effects?

A

A/E: Neuroleptic Malignant Syndrome - Symptoms include high fever, sweating, unstable blood pressure, stupor, muscular rigidity, and autonomic dysfunction.

Weight gain

69
Q

Prochlorperazine class and indications?

A

Antipsychotic – D1 + D2 antagonist - - Anti-emetic

VERTIGO m/c use
Anti-emetic for chemo

Psychotic disorders symptomatic management - - short term mgmt of non-psychotic anxiety in GAD
Severe nausea and vomiting of various causes

70
Q

Prochlorperazine interactions, contraindications, cautions, adverse effects?

A

A/E: Sedation - Hypotension

Neuroleptic Malignant Syndrome

Symptoms include high fever, sweating, unstable blood pressure, stupor, muscular rigidity, and autonomic dysfunction

71
Q

Aripriprazole class and indications?

A

Schizophrenia - - Bipolar Disorder Type I (manic depression). Tablet or extended release injection.

72
Q

Aripriprazole interactions, contraindications, cautions, adverse effects?

A

A/E: Dizziness - Lightheadedness - Weight Gain - Salivation - Insomnia

Neuroleptic Malignant Syndrome

Symptoms include high fever, sweating, unstable blood pressure, stupor, muscular rigidity, and autonomic dysfunction

73
Q

Haloperidol class and indications?

A

Typical Antipsychotic
Schizophrenia - - Tourettes (tics) - - Mania in Bipolar Disorder - - Alcohol withdrawal nausea, vomiting, delirium, agitation, psychosis, hallucinations - - Oral, IM or IV - - short acting or long acting injection in Schizophrenia

74
Q

Haloperidol interactions, contraindications, cautions, adverse effects?

A

A/E: Neuroleptic Malignant Syndrome

Symptoms include high fever, sweating, unstable blood pressure, stupor, muscular rigidity, and autonomic dysfunction

Injection site reaction

CI: Previous history of acute stroke or coma.
Severe intoxication with alcohol or any other drug that acts as a central nervous system depressant.
Heart disease.
Allergy to haloperidol or other drugs of the butyrophene class.

75
Q

Antidepressants

A 
Amitriptyline
Fluoxetine
Escitalopram
Venlafaxine
Bupropion
Vaemicline
Trazodone
Phenelzine
76
Q

Amitriptyline class and indications?

A

Tricyclic

Mood depression - - Chronic pain

77
Q

Amitriptyline interactions, contraindications, cautions, adverse effects?

A

A/E: Anti-cholinergic activity -> Dry mouth, dizziness, tremor, blurred vision
Anti-histaminergic -> sedation, weight gain

CI: CV disease - hx of MI, CAD, arrhythmias

78
Q

Fluoxetine class and indications?

A

SSRI
Depression - - OCD - - Bulimia nervosa - - Anorexia nervosa - - Fibromyalgia - - Panic attacks - - Phobia - - Premenstrual Dysphoric Disorder (PMS/PMDD)

79
Q

Fluoxetine interactions, contraindications, cautions, adverse effects?

A

A/E: Suicidality in persons below age 24

Anorexia, insomnia, sexual dysfunction, risk of GI bleed

INT: 5-HTP, Tryptophan

80
Q

Escitalopram class and indications?

A

SSRI

Major Depressive Disorder - - GAD Anxiety

81
Q

Escitalopram interactions, contraindications, cautions, adverse effects?

A

A/E: Suicidality in persons below age 24

Anorexia, insomnia, sexual dysfunction, risk of GI bleed

INT: 5-HTP, Tryptophan

82
Q

Venlafaxine class and indications?

A

Effexor
SNRI

Major Depressive Disorder - - GAD Anxiety - - Panic Disorder - - Social Phobia
Second line anti-depressant - - equal efficacy to Citalopram but higher incidence of suicide and other adverse effects

83
Q

Venlafaxine interactions, contraindications, cautions, adverse effects?

A

3

84
Q

Bupropion class and indications?

A

Atypical Antidepressant - Serotonin Antagonist and Reuptake Inhibitor (SARI)
Depression - - Smoking cessation

85
Q

Bupropion interactions, contraindications, cautions, adverse effects?

A

A/E: Agitation - Insomnia - Anorexia - but does not cause weight gain or sexual dysfunction

CI: Eating disorders

86
Q

Vaemicline class and indications?

A

Atypical Antidepressant - Nicotine Receptor Partial Agonist

Nicotine addiction - - Partial nicotine receptor agonist stimulates nicotinic receptors more weakly than nicotine - Contrast w/ nicotinic antagonist Bupropion and nicotine replacement therapy (patch, gum)

87
Q

Vaemicline interactions, contraindications, cautions, adverse effects?

A

7

88
Q

Trazodone class and indications?

A

8

89
Q

Trazodone interactions, contraindications, cautions, adverse effects?

A

Atypical Antidepressant - Triazolpyridine derivative

Depression - - Panic - - Anxiety

90
Q

Phenelzine class and indications?

A

MAO Inhibitor

Atypical depression

91
Q

Bipolar disorder

A

Lithium

92
Q

Lithium class and indications?

A

Mood stablizer - - Anti-manic

Bipolar Affective Disorder
Monitor lithium, electrolytes, thoyroid, renal function – avoid changes in salt, coffee

93
Q

Lithium interactions, contraindications, cautions, adverse effects?

A

Caution - Monitor lithium, electrolytes, thoyroid, renal function – avoid changes in salt, coffee

94
Q

Opioid analgesics

A 
Codeine
Hydrocodone
Oxycodone
Methadone
Morphine
Naltrexone
95
Q

Codeine class and indications?

A

Opioid agonist - - Anti-tussive

Pain (mild to moderate) - - Cough suppressant - - Acute diarrhea

96
Q

Codeine interactions, contraindications, cautions, adverse effects?

A

6

97
Q

Hydrocodone class and indications?

A

Opioid agonist - - Anti-tussive

Pain (moderate to severe) - - Cough suppressant

98
Q

Hydrocodone interactions, contraindications, cautions, adverse effects?

A

8

99
Q

Oxycodone class and indications?

A

Opioid agonist

100
Q

Oxycodone interactions, contraindications, cautions, adverse effects?

A

Pain (moderate to severe)

101
Q

Methadone class and indications?

A

Opioid agonist

Pain - - Opioid dependence - - Heroin detoxification

102
Q

Methadone interactions, contraindications, cautions, adverse effects?

A

2

103
Q

Morphine class and indications?

A

Opioid agonist

Pain (moderate to severe) - - Cough - - Analgesia during labor

104
Q

Morphine interactions, contraindications, cautions, adverse effects?

A

4

105
Q

Naltrexone class and indications?

A

Opioid agonist

Opioid dependence - - Adjunct in alcohol dependence
Competitive antagonist at opioid receptor sites – blocks action of opioids and precipitates withdrawal sx in opioid dependent individuals

106
Q

Naltrexone interactions, contraindications, cautions, adverse effects?

A

6

107
Q

Migraine

A

Sumatriptan
Caffeine
Propanolol -> Migraine Prophylaxis
Pregabalin -> Migraine Prophylaxis

108
Q

Sumatriptan class and indications?

A

Vascular headache suppressant
Selective 5-HT1 agonist

Migraine headache

109
Q

Sumatriptan interactions, contraindications, cautions, adverse effects?

A

9

110
Q

Caffeine class and indications?

A

CNS stimulant

Migraine headache

111
Q

Caffeine interactions, contraindications, cautions, adverse effects?

A

1

112
Q

Recreational drugs

A

2

113
Q

Cannabis class and indications?

A

Cannabinoid

Pain analgesia - - Anti-emetic - - Appetite stimulant - - Glaucoma

114
Q

Cannabis interactions, contraindications, cautions, adverse effects?

A

4

115
Q

Cocaine class and indications?

A

Amino Ester - - Anesthetic

For introduction of local (topical) anesthesia of accessible mucous membranes of oral, nasal, laryngeal cavities

116
Q

Cocaine interactions, contraindications, cautions, adverse effects?

A

6

117
Q

Heroin class and indications?

A

Narcotic - - Opioid agonist

Acute pain - - MI - - Acute pulmonary edema - - Chronic pain

118
Q

Heroin interactions, contraindications, cautions, adverse effects?

A

8

Baloney (37 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions