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Kaplan: CNS Pharmacology > Drugs of Abuse > Flashcards

Drugs of Abuse Flashcards

1
Q

What MOA (so besides blocking reuptake of DA, NE, and 5HT) what causes analgesic effects of cocaine?

A

local anesthetic action from Na+ channel blockade

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2
Q

MDMA other name and MOA? S/E?

A

“ecstasy” amphetamine-like with strong 5HT pharmacology and therefore hallucogenic and generally neurotoxic

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3
Q

Hallucinogens primarily implicate which receptors?

A

5HT

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4
Q

What are the effects of using Hallucinogens?

A

hallucination, sympathomimetic response, causes dyskinesias

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5
Q

Marijuana MOA?

A

interaction of THC with CB1 and CB2 cannabinoid receptors in CNS and periphery

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6
Q

What are the effects of using marijuana?

A

sedation, euphoria, inc. HR, conjunctival irritation, delusions, hallucinations

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Kaplan: CNS Pharmacology (8 decks)

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