Drugs of the Day 1

Question 1

Acetylcysteine

Answer 1

B: Mucomyst
C: Mucolytic and Antidote

SE: Nephrotoxicity,

U: Tylenol Overdose, Atelectasis(lung collaps)

Question 2

Acyclovir

Answer 2

B: Zovirax
C: Antiviral
U: Herpes Zoster, Varicellar Zoster

SE: Acute Kidney Injury

Question 3

Adenosine

Answer 3

B: Adenocard
C: Class V antiarrhythmic
SE: Arrhythmias
U: PSVT,

Question 4

Alteplase

Answer 4

B: Activase
C: Thrombolytic Agent

U: disintegrate blood clots,
restore central venous catheter function (IV Line)

SE: MI, Stroke, Pulmonary embolism

Question 5

Amikacin

Answer 5

B: Amikin
C: Aminoglycoside Antibiotic

U: SERIOUS multi-drug resistant Gram
negative infections(Pseudomonas)

SE: Nephrotoxicity, Ototoxicity, Narrow therapeutic window, Draw peak and trough levels

Question 6

Amiodarone

Answer 6

B: Cordarone
C: Class 3 antiarrhythmic

U: arrhythmia, atrial fibrillation

SE: Hypo/Hyperthyroidism, Pulmonary toxicity, increased
liver function tests

DI: Many!!!!! Including warfarin which could increase
the risk of bleeding.

Question 7

Amphotericin B

Answer 7

B: Fungizone
C: Antifungal

U: Fungal Infections, Immunocompromised patients

SE: Nephrotoxicity, Infusion-related reactions if not premedicated with Ibuprofen,
hypokalemia(arrhythmias) , anemia

Question 8

Ampicillin

Answer 8

B: N/A
C: Penicillin Antibiotic

U: Bacterial infections

SE: Hypersensitivity Reaction (cross-sensitivity with
cephalosporins and carbapenems.)

Cidal and DOC

Question 9

Ampicillin / Sulbactam (B-Lactamase inhibitor)

Answer 9

B: Unasyn
C: Penicillin Antibiotic

U: Bacterial Infections, skin/soft tissue infections (Celulitis)

SE: Hypersensitivity Reaction (cross-sensitivity with
cephalosporins and carbapenems.)

Question 10

Atropine

Answer 10

B: N/A
C: Anticholinergic / Antispasmodic

U: used before operation to decrease salivation and
secretions, also used to treat bradycardia

SE: Anticholinergic SE

Question 11

Azithromycin

Answer 11

B: Zithromax
C: Macrolide Antibiotic

U: Community acquired pneumonia/upper respiratory tract infections, MAC in AIDS patient, immunocompromised patient

static

SE: QT prolongation

Question 12

Aztreonam

Answer 12

B: Azactam
C: Monobactam Antibiotic

Cidal, NO cross sensitivity w/ other B-lactam

U: Gram-negative infections only (Pseudomonas)

Question 13

Bumetanide

Answer 13

B: Bumex
C: Loop Diuretic

U: Edema associated with heart failure, renal, and/or liver disease

SE: Dehydration, Hypokalemia, Hyponatremia

Question 14

Buprenorphine

Answer 14

B: Buprenex
C: Mixed opiate agonist/ antagonist

U: Heroin Withdrawal, Moderate to severe pain,

SE: Constipation, circulatory and respiratory depression

Question 15

Caspofungin IV only

Answer 15

B: Cancidas
C: Antifungal

U: nvasive fungal infections (i.e. candida,
Aspergillus).

SE: Anemia, Immunocompromised patients

Question 16

Cefazolin

Answer 16

B: Ancef
C: 1st generation Cephalosporin antibiotic

U: Skin and soft tissue infection (not MRSA), Surgical prophylaxis

SE: Hypersensitivity, Cross Sensitivity

Cidal

Question 17

Cefepime

Answer 17

B: Maxipime
C: 4th generation Cephalosporin antibiotic

U: Hospital infection by Pseudomonas & Gram -ve rods, Immunosuppressed patient, fever

Question 18

Cefotaxime

Answer 18

B: Claforan
C: 3rd generation Cephalosporin antibiotic

U: Lower respiratory tract infections, Some pediatric infections

NO Pseudomonas

Question 19

Ceftazidime

Answer 19

B: Tazicef
C: 3rd generation Cephalosporin antibiotic

U: Nosocomial infections caused by Pseudomonas and other multidrug
resistant Gram negative rods

Question 20

Ceftriaxone

Answer 20

B: Rocephin
C: 3rd generation Cephalosporin antibiotic

U:Community acquired pneumonia (in conjunction with a Macrolide)

IM for Gonorrhea

NOT Pseudomonas, & Neonates

SE: Biliary Sludging

Question 21

Chlorpromazine

Answer 21

B: Thorazine
C: Typical Antipsychotic

U: Psychosis, Nausea/vomiting, DOC for intractable hiccups

SE: QT prolongation,
mask Parkinson’s, Extrapyramidal Effects (EPS), Tardive Dyskinesias, Sedating effects

Question 22

Ciprofloxacin

Answer 22

B: Cipro
C: Fluoroquinolone Antibiotic

U: UTI, Hospital pneumonia W/ combination therapy.

SE: QT Prolongation, tendon rupture,

Not for HTN, PVD, history of aneurysm, not for <18YO, not for pregnant women.

Cidal

Question 23

Cisplatin

Answer 23

B: Platinol
C: Antineoplastic

U: Bladder, testicular, and ovarian cancers.

SE: Ototoxicity, Nephrotoxicity, Neurotoxicity(seizures), GI toxicity

Question 24

Clindamycin

Answer 24

B: Cleocin
C: Lincosamide Antibiotic

U:
Anaerobic Infections (some MRSA Strain), Prophylaxis for dental procedures

SE: N/V/D, Clostridium difficile

Static

Question 25

Daptomycin

Answer 25

B: Cubicin C: Lipopeptide Antibiotic U: Skin and soft tissue infections caused by MRSA or other susceptible Gram + bacteria SE: Rhabdomyolysis, Cidal

Question 26

Darbepoetin Alfa

Answer 26

B: Aranesp C: Colony Stimulating Factor U: Anemia associated with chronic renal failure or chemotherapy SE: Hypertension, infection BBW: Increase due to clots, MI, Stroke, VTE

Question 27

Dexamethasone

Answer 27

B: Decadron C: Glucocorticosteroid U: Pulmonary diseases, Septic shock, Cerebral edema, Preterm labor (to help with fetal lung maturation) SE: Cushings syndrome, psychosis, osteoporosis Lab Values: increase WBC, Glucose Taper down if more than 7 days

Question 28

Diazepam

Answer 28

B: Valium C: LA Benzodiazepine U: Status epilepticus, Anxiety, Adjunct to anesthesia SE: Sedation, hypotension, bradycardia, and respiratory depression, decrease HR, BP, RR

Question 29

Digoxin

Answer 29

B: Lanoxin C: Miscellaneous Antiarrhythmic U: Heart failure, Atrial fibrillation SE: Bradycardia Drug TOX: GI, CNS(yellow halos), and arrhythmias Must have levels

Question 30

Diltiazem

Answer 30

B: Cardizem C: Non-dihydropyridine Calcium Channel Blocker U: Atrial fibrillation, Angina SE: Bradycardia, hypotension

Question 31

Diphenhydramine

Answer 31

B: Benadryl C: H1 Histamine antagonist U: Anaphylactoid reactions, Insomnia U: Anticholinergic

Question 32

Dobutamine

Answer 32

B: Dobutrex C: Positive Inotrope U: Cardiogenic shock SE: Tachycardia, angina, increased blood pressure Not first line agent, mostly ICU

Question 33

Dolasetron

Answer 33

B: Anzemet C: Serotonin Receptor Antagonist U: Prevention and treatment of nausea and vomiting SE: QT prolongation, increased serotonin syndrome,

Question 34

Dopamine

Answer 34

B: Intropin C: Vasopressor U: Cardiogenic shock SE: Tachycardia, angina ICU only

Question 35

Doripenem

Answer 35

B: Doribax C: Carbapenem Antibiotic U: Broad spectrum antibiotic used for multi-drug resistant organisms including Pseudomonas Warnings: Watch cross sensitivity with penicillins/cephalosporins. Cidal

Question 36

QT Prolongation

Answer 36

Azithromycin, Ciprofloxacin, Dolasetron, Chlorpromazine

Question 37

Cidal

Answer 37

Ampicillin, Aztreonam, Cefazolin, Ciprofloxacin, Daptomycin, Doripenem

Question 38

Atrial fibrillation

Answer 38

Amiodarone, Digoxin, Diltiazem,

Question 39

Nephrotoxicity

Answer 39

Amphotericin B, Acetylcysteine,