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Depression > DSM-5 criteria > Flashcards

DSM-5 criteria Flashcards

(54 cards)

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1
Q

Criteria for depression

A

Mood - depressed
Sleep - increased/decreased
Interest/pleasure - diminished
Guilt or feeling of worthlessness
Energy - decreased
Concentration - decreased
Appetite - increased/decreased
Pyschomotor agitation or retardation
Suicidal Ideation
M SIG E CAPS

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2
Q

Why is it important to rule out Bipolar before starting antidepressants

A

could induce mania or rapid cyclying

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3
Q

Drugs that can worsen depression

A

Atomoxetine
Indomethacin
Efavirenz
Rilpivirine
Beta blockers
Hormonal Contraceptives
Anabolic steroids
Benzodiazepines
systemic steroids
Interferons
Varenicline
Ethanol

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4
Q

How long should antidepressants be given to work

A

4-8 wks

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5
Q

Medication that increase serotonin syndrome

A

SSRI
SNRI
TCAs
Fentanyl
methadone
lithium
tramadol
buspirone
triptans
St Johns wort

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6
Q

Serotonin syndrome symptoms

A

severe nausea
dizziness
HA
diarrhea
agitation
tachycardia
hallucinations

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7
Q

What should be done to when stopping antidepressants

A

taper over several weeks

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8
Q

What SSRI self tapers

A

Fluoxetine because of long half life

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9
Q

What drugs are used to augment with antidepressants

A

Buspirone
Low dose atypical antipsychotic
abilify
olanzapine + fluoxetine
Seroquel XR
brexpiprazole
Esketamine
Lithium

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10
Q

What antidepressants can be used initially for pregancy

A

SSRI

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11
Q

Postpartum drugs that are preferred to be used

A

SSRI
TCAs

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12
Q

What SSRI shoudl not be used in pregancy

A

paroxetine

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13
Q

What TCA should not be used for postpartum depression

A

doxepin

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14
Q

SSRI MOA

A

increase 5-HT

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15
Q

Celexa

A

citalopram

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16
Q

lexapro

A

escitalopram

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17
Q

prozac

A

fluoxetine

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18
Q

Sarafem

A

fluoxetine

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19
Q

Paroxetine

A

paxil

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20
Q

sertraline

A

zoloft

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21
Q

max dosing celexa

A

40mg/ day

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22
Q

celexa dosing

23
Q

Lexapro max dosing

24
Q

celexa max dosing > 60yrs

25
lexapro max dosing > 60yrs old
10mg/day
26
Prozac max dosing
80mg/day
27
Prozac dosing
10-60mg/day
28
Symbyax
fluoxetine + olanzapine
29
Sarafem indication
prementral dysphoric disorder
30
symbyax indication
treatment resistant depression
31
brisdelle indication
vasomotor symptoms
32
brisdelle
paroextine
33
sarafem dosing
20mg/day
34
Paxil IR dosing
10-60mg/day
35
Paxil CR dosing
12.5-62.5mg/day
36
sertraline
zoloft
37
zoloft dosing
50-200mg/day
38
contraindication with SSRIs
MAOI Inhibitors linexolid IV Methyline blue pimozide
39
What disorder should not be used with brisdelle
pregnancy
40
Warning for SSRIs
QT prolongation hyponatremia fall risk bleeding
41
Side Effects of SSRIs
decreased libido ejaculation difficulties erectile dysfunction somnolence insomnia nausea dry mouth diaphoresis weakness tremor diszziness HA
42
Most activating SSRI
fluoxetine
43
Most sedating
paroxetine
44
What SSRI is preferred in pt with cardiac risk
sertraline
45
What is the washout period with SSRIs and MAOIs
two week 5 weeks with fluoxetine b/c of half life
46
QT prolongation is see most consistantly with which SSRIs
lexapro and celexa
47
fluoxetine and paroxetine inhibit what liver enzyme
CYP2D6
48
what is the preferred SNRI with tamoxifen
Venlafaxine
49
Vilazodone
Viibryd
50
Viibryd MOA
SSRI and -HT1A partial Agonist
51
Vortioxetine
trintellix
52
Trintellx MOA
SSRI and 5HT3 antagonist and 5HT1A agonist
53
Viibryd should be taken with food T/F
True
54

Depression (1 decks)

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