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Dvt Flashcards

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1
Q

Blue man syndrome

A

Amiodarone

So many effecets

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2
Q

Drug of choice for torsade de points

A

Iv mgso4

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3
Q

Atropine

A

Used for sinus brady cardia

Second degree heart block

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4
Q

Drig of choice for emergrncy hyperkalemia

A

Insulin+glucose calcium gluconate

Salbutamol

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5
Q

Tapid relief of braethlessness in ccf

A

Furosemide morphine

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6
Q

Omecamitiv

A

Direct myosine activator

Positive ionotropic

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7
Q

Nesiritide

A

Bnp

Only iv

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8
Q

Neprylisina inhibitor

A

Ecadotril sacubitril

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9
Q

Drug contraindicated in b/ l renal artey stenoais

A

ACE inhibitors

ARBs

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10
Q

Hypertension plus dm frat lime of antihypertensives

A

Ace>arbs> ccb

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11
Q

Antihypertenaive having Uricosuric action

A

Losartan amlodipine

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12
Q

Safe antihypertensive in pregmancy

A

Labetalol

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13
Q

Direct guanyl cyclase activators

A

Riiocoguqtcinociguat

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14
Q

Most preferred diuretic for ascitia dute to liver failure

A

Spirinoloactone

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15
Q

Contarindicated diuretic in liver failure

A

Acetazolamide

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16
Q

Rapid symptom relief in in pulmonary edema

A

Furosemide

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17
Q

Diseaase modifier in pulmonary edema

A

Spironolactone

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18
Q

Which diuretic cause stome formation

A

Loop diuretic

Ex thiazide

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19
Q

Diurteic for mountain sickens

A

Acetazolamide

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20
Q

Doc for hypercalcuria or williams syndrome

A

Thiazide

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21
Q

Diruteic sfor hirsuitism and pcos

A

Spirinolactone

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22
Q

For cystic finrosis diuretic?

A

Amiloride

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23
Q

Thrombolytic agents are mainly used for

A

Stemi

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24
Q

Best antidote for thrombolityit induced bleeding

A

Eaca

Tranexamic acid

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25
Anticoagulant causes hupercoagulation dermal necrosis and purple toe syndrome
Warafarin
26
Warfarin antidote
Phytonadione k1
27
Direct factor 2 a inhibitor
Dabigatran
28
Antidote for dabigatran
Iv idarucizamab
29
Sea sickness
Meclizine
30
Morning sickness
Doxylamine plus vit b6
31
Motion sickness vomiting
Scopolomine(hyoscine)
32
Anti emetic causing acute dystonia
Metoclopramide
33
Red eye caused by
Nebilone
34
Melanosiis coli caused by
Sennna laxative
35
Doc for ins causing ischemic colitis
.alosetron | 5ht3 antagonist
36
Guany l cyclase activator
Linaclotise Plecanatide For constipation
37
Lubiprostone
Type 2 chloride channel avtivator
38
Somatostatin analoge useful for acromagly and vushing syndromw
Pasiretide
39
Growth hormone recptor blocker
Pegvisomet
40
Dwarfism drugs
``` Sermorelin Hexarelin Tesamorelin -all areGH RF Growth hormone Somatrem Sonatropin ```
41
Hyperprolactemia
Cabergoline
42
Pph drug
Methyl ergometrine
43
Anti diabetic acting on brain
Bromocroptine | Pramlintide
44
Insulin secretagogue
Sulfonyl urea Maglinitides Glob1 analogue Dpp4 inhibitor
45
Anti diabetic drug acting on kidney
Sglt2
46
Name one glp2
Shor
47
Ultra short acting insulin
Lispro aspart glusine
48
Insulin absorbtion
Abd>
49
Antidiabetic approved for obesity
Liraglutide | Semaglutide
50
Drug approved for both dm 1 and 2
Insulin | Pramlinitide
51
Antidiabeti having tisk of medullary ca of thyroid
glp1 analogue
52
Antidiabetic having lung cancer risk
Afreeza inhalable insulin
53
Macular edema
Pioglitazone
54
Antidiabetic causing uti
Sglt2 inhibitor
55
Antidiabetic causing urti
Dppt 4 inhibitor
56
Only one sfe of kidney
Liraglutide
57
Injectable agent for erectile dyafunction
Alprostadik Phentolamine Papacerine
58
Antihypertensine causing erectile dysfunction
Thiazide | Beta blockers
59
Sterioid for lung maturation in preterm baby
Betamethazone-12 mg every 24 hrw 2 dises | Dexamerhazone 6 mg 4 dose 12 hrs apart
60
Drugs causes oateonecroais of femur neck
Steroid
61
Osteonecroais of jawm.
Bisphosphanates
62
Drug inhibiting osteoclast
Bisphosphantae Denosumab Raloxifen
63
Promotes osteoblast
Teriparatide Abaoparatide Vit d Calcium
64
Dual action both osticlastic and osteoblastic
Strontium ranelate
65
Name for myasthenia grqvis
Pyridostigmine | Neoatigmine
66
Drug for sx of kyasthenia
Edrophonium short acting
67
Alzheimer disease
Chollinegic enhancers
68
Anti smoking drugs effective
Varenicline
69
Name alpha 2 agonist used as centrally acting mr
Tizanidine
70
Adrenwrgic agonist for cardiac stress test
Dobutamine
71
Beta blocker causing qt prolongation
Sotelol
72
Doc for hocm alathesia
Propranolol
73
Antiepileptic for obesity
Zonisamide and topi ramate
74
Antidepressants for obseity
Buoropione
75
Antidiabetic for rx of obesity
Liraglutide | Semaglutide
76
D2 blocking antipsychotic
Phenothiazine Thioxqnthems Butyriophenones
77
Tardive dyakinesia rx
Valbenezine-vmat 2 inhibitor
78
Eps
Trihexyphenifyk
79
Malignant neuroleptic syndrome
Dantrolene
80
Atypical antipsychotics causing myocarditis hypersalivation agranulocytosis
Closapine
81
Antipsychotic for anti aduicidal action
Clozapine
82
Catarct causing antipsychotic
Quitiapine
83
Atypical antipsychotic causing ot prolongation
Ziprasidone
84
Metabolic syndrome
Closapine Olanzapine Quitiapine
85
Parkinson ds paychoais
Pimavanserin
86
Cheese reaction
Phentolamine
87
Drug for depression ocd ptsd bulimia | Premature ejaculation
Ssri
88
Antidepressants for smoking control
Bupropion Adhd Obesity
89
Herbal medice for depression
St johns wort
90
Ssri averae reaction in delayed ejaculation
Trazadone
91
Hypo active sexual sesire disorde in female
Flibanserin | Bremelanotide
92
Postparatum depruas
Breslonolo
93
Opiod deaddiction
Methadone | Buprenorphine
94
Opiod withdrawl stmptom
Lofexidine
95
St anthonys fire
Ergotism | Gamgrene
96
Most commonest for prophylactic for migrane
Beta blocker
97
Cgrp antagonisit
Olcegepant | Talcagepant
98
Drugs cauing uveitis
Btimonidine | rifabutin
99
Whorl like pattern in cornea
Amioloride
100
Bulls eye retinopathy
Chloroquine
101
Lid lag
Apraclonidine
102
Bronchoapsam causing drigs
Beta blockers
103
Heterochromia irisia
Lantanipriat | Bimatoproat
104
Red eye
Dipivefrine
105
Vgfr blocker
Bevacizumab | Etc
106
Gtcs
Valproate>lamotrigine
107
Absenwce seizue
E>v>l
108
Atupical seizures
V>l> t
109
Febrile seizure
Diazepam | Midazolam
110
Safest antiepileptic in pregnancyy
Levitaracetam>lamotignine
111
Infantile spasm and tuberous sclerosis
Vagabatrin
112
Phenytoin mc advereseceffet
Hyperplasia of gums
113
Carbamazapine
``` Steven johnososn syndromhepatotoxic Aplastic anemia Diplopia Ataxia Siadh Esonophiloa ```
114
Valproate
``` All types of epilepsy Prophylaxis of migraine Mood stabilizers in bipolar disesa Se Vomiting Alopecia Liver toxic in children Rashes Obeaity Amonia increse leads to encephalopathy-rx l carnitine) Tremors ``` Pancratand pcos
115
Antiepileptic cause wt loss
``` Topiramide Zonisammide But causes Nephrolitjiasis Angle closure glucoma Carbonic anhydrqzie activity ```
116
Increase memory
Leviteracetram | Bivaracetam
117
Antiepileptic cause frequent eye check up
Vigabatrine Ezogabine Topiramate
118
Toxin leads to parkinsons diseae
mptp toxin
119
Levodopa contra indicated in
Angle cloaure glucoma cause mudriasis | Melanoma produce melanin
120
Drug induced parkinsonis
Benshexol
121
Restless leg syndrome
Ropinrol doc | Pramipexol
122
Huntingtons d/s
Excessive dopamine Vmat 2 inhibitor-tetra benazine -doc Deutetrabenazine
123
Tourette syndrome
Guanfacine>clonidine
124
Amyotrophic lateral sclerosis lou gehrigs ds
Riluzole nmda antagoniat
125
Progeria stndrome
Lonafarnib
126
Mutiple aclerosis
Mc donald criteria Relapse ma-interferon beta Spms- mitoxantrine> interferon beta Ppms-ocrelizumab cd 20 blocker
127
Maximum improvement in mutiple sclerosis inedda scale
Mitoxantrone>natalizumab
128
Natalizumab se
Progressive mutifocal leucoencephalopathy
129
Moat comkon process of absoprption
Aimple passive diiffusion non ionized drug absorbed
130
High first pass metabolism in liver
Lignocaine | Sterioidal hormone
131
Bioavailability
F= auc oral/auc iv | Auc area under cover
132
T max C max Auc
T max rate of absorbtion C max max concent Auc extend of annsorbtion
133
Highest volume of depoaition
Chloroquine
134
Plasma protein binding of srugs | Acidic drug bind to albumin
Basic drugs bind to alpha 1 acid glycoproteins
135
Forced alkaline diuresis by
Sodium carbonate
136
Forced acid diureis by
Amkonium choride
137
Why sulphonimide ci in neonate and last trimester of preg
Kerniteris
138
Qt prolongation doc
Mgso4
139
Patient with alzheimer meed rx for overactive bladder best doc
Trospium (anticholinergic which doesn’t cross blood brain barrier)
140
Direct guanyl cyclase activator used in primary htn
Riociguat
141
Apoxaben action reveresed by(oral anticoagulant)
Andexamet alpha
142
Thiazide effective even in the presence of kidney failure
Metolazone
143
Adverse effects of cholesterol lowering agents
Cutaneous flushing-niacin Oily stools- ezetimibe Gall stone-fenofibrate(ppar alpha agonists) Myalgia-rosuvastatin
144
Statin cause adverse effecta
Hepatotoxic myopathy
145
Newly dxed hyperthyroidism in frst trimester pregnancy suitable doc
Propulthiouracil-strong protein hinding less chance of crossing placenta
146
Antidiabetic drug and aote of action
Pramilintid-hind brain Empaglifozine-kidney Miglit-small intestine Pioglitazone-adipose tissue
147
Antidiabeti drugs and advereseeffecta
Exenatide-pancreatitis Sitagliptin-nasopharyngitis Dapaglifozin-hypotension Pioglitazone-fluid retension
148
To control postprandial blood glucose which id better insulin
Short acting lispro | Oral meglinitide
149
Serm and its indications
Ospemifenw-dyspareunia Ormiloxafene-contraception Clomiphine-
150
Monoclonal ab useful in osteoporosis targetingagainst RAnk l
Denosumab
151
Depression pt with sssri developed sexual dysfunction whichbis suitable
Mirtazapine minimal sexual dysfunction
152
Drig used for Rx of opoid poisoning and prevention of relapse of opiod habit
Naltrexone
153
Drug forBronchial asthama targeting against il 4
Dupilimab
154
Vegfr for rx of ARMD
Pegaptanib
155
Child with influeza aspirin ci becosz
Reyes syndrome | Fulminant hepatic failure dur to aspirin
156
Moa of dapsone for bacterial and fungal infection
Competition with paba in follic acid synthesis
157
Drugs in late trimester which cause increased seruk unconjugated bilirunin in neonate
Cotrimoxazole which contain a sufomide
158
Girl on antiepileptic for 6 months No further eposodes eeg and ct normal Wat further line of mx
Continue antiepileptic for 2 years and then slowly taper
159
Thyroud hormone act on
Intracellular receptor(nuclear receptors)
160
Drug binfld to fk bing protein inhibit calcineurin leading to immunosuppression
Tacrolimus/fk506
161
Frst kine drug of choice gir angina
Beta blockers (decrease worklod(hr))>ccb(decre HR,Incre blood flow)>nitrates(decres work load))
162
Nitrates and sildenafil dont give together
Severe hypotensive shock
163
Which antianginal drug cause aphthous ulcers
Nicorandil
164
Antianginalbdrug aggrevating movement disorde
Trimetazidine
165
Antianginal drug causing luminous phenomena
Ivabradine
166
Rx of atrial fibrillation
2 group of drugs 1)rate controller—beta blockers ,ccb,digoxin—acting onAV node 2)rhytm reveersal-class 3 anti arrythmic k+ channel blocking Ibutilide Dofetilide Amiidarone Vernakalent
167
Antivoagulant used in prevention of thrombus in AF
Directly acting oral anticoagulant or vitamin k antagoniat like warfarin
168
Doc of acute svt
Iv adenosine>iv verpemil
169
Prwvention of recurrence of svt
Oral beta blockers Oral verapemil Oral amiodarone
170
Ecg with delta wave pr interval<120
Wpw syndrome | Abnormal fibres connecting ateioventricukar
171
Doc for arrythmia in wpw syndrome
``` Flecanaide-class 1c Procqinqmide-class 1 a ```
172
Rx foe wpw syndrome
Radio frequency ablation
173
Doc for vt according to acls
Amiodarone | Lignocaine
174
Rx of choice for vt
Dc ahock
175
Antidote for mgso4
Calcium gluconate
176
Doc dor congenital qt
Propranalol
177
Disese modifying drugs in ccf
Beta blockers Acei Arbs Spironolactone
178
Calcium sensitisor drugs for ccf
Pimibendan | Levosimendan
179
Drug inhibiting both ace and neprylisin
Omapatrilat,sampatrilat
180
Drug which causing angio edema
Ace inhibitir due to bradykininaccumulation
181
Absolute ci antihyoertensive in pregnanacg
Ace i | Arbs
182
Rh i kinase inhibitir for rx of pilmonary htb
Fasudi
183
Diuretic ci in pulmonary edema
Mannitol
184
Diuretic used in awrosol cystic fibrosis
Amiloride | Improves mucociliart swcretion
185
Doc for lithium insuced siabetes insipidua
Amiloride
186
Doc for cranial di
Desmopressin
187
Doc for nephrogenic di
Thiazides
188
Direct xa factor inhibitors
Apixaban Rivaroxaban Edoxaban Betrixaban
189
Common antidote for 2a and xa inhibitors
Ciraparantag
190
How statins reduce ldl levels
By upregulation of ldl receptors at hepatocyte surface | Also decrese total cholesterol
191
Pcsk9 inhibitir for reduction of ldl
Alirocumab | Evolocumab
192
Drug which decrease the absorption of dietry choleaterol
Ezetimibe | Adv effect steatorrhiea
193
Bronchodialators
Beta 2 agonists Methyl xanthines M3 blockers
194
Moat important adverse effect of salbutamol(beta 2 agonists)
Tremor
195
Along with laba in order to prevent desensitization which drug used
Inhalable corticosteroid
196
M3 blockers for bronchodialation
Ipratropium | Cause paradoxical bronchospasm
197
Methyl xanthines as bronchodialtors
``` Tgeophylline,amino phylline Adv effects of theophylline Seizure Diuresis Arrythmia ```
198
Monoclonal ab used for bronchial asthma
Omalizumab igE MepoliUmab iL5 Reslizumab iL 5 Benralizumab iL 5
199
Cholinergic drug used for dx of asthma
Methacholine(challenge test)
200
How ppi have longer duration of action eventhough it has short half life
Irreversible blockage of h+ k+atpase pump
201
Drig interaction pf omeprazole
Clopidogrel Clopidogrel is a prodrug which need activation But omeprazole inhibit cyp2c19
202
Adv effects of ppi
Vit b12 deficienc | Hio bone fracture
203
Name one drug useful for gastritis which cause teratogenicity im pregnancy
Misoprostol | Moebiua ayndrome-6.7 cn danage
204
Ulcerprotectuve which cause black colour tongue
Bismuth
205
Anticholinergic for gastritisris
Pirenzepine Telezepine Both are m1 antagonist
206
Neuronkinin 1 antagonist for late phase vomiting
Aprepitant Fosaprepitant Rolapitant Neupitant
207
Longest acying 5 ht3 blocker
Palinosetron
208
Anti emetic having apetite atimulating action
Cannabinoids Nabilone Dronabinol
209
Antiemetic causes head ache
Ondansetrin
210
Cftr ingibitor
Croflemer | Use-hiv diarrhoea
211
Atosiban
Oxytocin receptor antagoniat | Tocokytic
212
Antithyroid drug causing agranulocytoasis
Methimazole
213
Antithyroid causing angioedema
Ligols iodine
214
Non thyroidal drug causing hypothyroidism
Lithium
215
Anti tb drugs cqusing hypothyroidism
Ethionamide | Pas
216
Antidiabetic acting onnliver
Metformin | Pramlintide
217
Antidiabetic acting on adipose and muscle tissue casuing insulin sensitization
Metformin | Pioglitazone
218
Glp2 inhibtor for short bowel syndrome
Teduglutide
219
Female sexual stimulants
Flibanserin | Bremelanotide
220
Dysmorphic eye lash caused by
Erlitinib
221
Crystallibe maculopathy
Tomixefen
222
Antidote for methyl alcohol
4-methyl pyrazole(fonipizole)
223
Antidote for atropine
Physostigmine
224
Antidote for beta blockers
Glucagon
225
Antidote for digoxin
Digibind
226
Antidote for morphine
Iv naloxone f/b oral naltrexone
227
Antidote for p mol
N acetyl cystine | Methinine
228
Antidote for benzodiazepines
Flumazenil
229
Chelating agent for lead,arsenic,mercury
BAL
230
BAL contraindicated in
Iron and casmium poisoning
231
Chelating agent for iron poisoning
Desferrioxamine Dexrazoxane Deferiprone
232
Chelating agent for cu poisoning
Zinc Trietine Tetrathiomolybdate
233
Hemodialysis done for which drugs
``` BLAST Barbiturates Lithium Alcohol Aspirin Salicylates Theophylline ```
234
No role for hemodyaliss which drugs
``` AVOID AB Amfetamine Verapamil warfarin Organophosphate Imipramine Digoxin Amiodrone Benzodiazepines Choroquine ```
235
Antidote for amfetamine
Ammonium chloride
236
Antidote for verapemil
Calcium gluconate
237
Antidote for warfarin
Vitamin k1
238
Antidote for tca poisoning
Sodium bicarbonate
239
Longest actimg antidepressant drugs
Fluoxetin
240
All ace inhibitors are pro drug except
Captopril and lisinopril
241
All phase 1 reactions of metabolism occurs in
Microsomes
242
Only microsomal phase 2 reaction
Glucoronide conjugation
243
CYP enzyme inducers
``` GPRS Griseofulvin Phenobarbitone Rifampicin Smokking Alcohol(chronic) ```
244
CYP enzyme inhibitirs
``` COKE IVC GAR Cimetidine Omeprazole Ketoconazole Erythromycin Isomiazid Valproate Ciprofloxacin Grape fruit juice Alcohol(acute) Ritonavir ```
245
Why rifampicin causes contraceptive failure
Rifampicin is a cyp inducer hence it increses cyp3a4
246
P glycoprotein
Efflux transporter Throw drug out of body Substrate—digoxin
247
P glycoprotein inducers
``` Rifampicin | Reduce digoxin plqsma concentration | Loss of effects ```
248
Pnglycoprotein inhibitors
``` QUACK Quinidine Verapamil Aniodarone Clarithro/erythromycin Ketoconazole ``` Increases plasma concentration of digoxin | Tixicity arrythmia
249
All pituitary hormones are g protein couoled receptors except
Growth hormone | Prolactin
250
First order kinetic
If the drug is reduced exponentially Elimination directly proportional to concentration Constant farction eliminated Half life is constant
251
Zero order kinetics
Drug decreased in linear pattern Elimination constant Constant amount eliminated Halflife proportional to concentration
252
Zeroborder kinetucs ahown by
``` Watt power Warfarin Alcohol and aspirin Theophylline Tolburamide Phenytoin ```
253
Pure zero order kinetics shown by
Alcohols
254
Pseudo zero order kinetics ahown by
Phenytoin
255
Loading dose=
Vd X target concentration | Target comcentration achieved after 4-5 halflives
256
Maintanance dose =
Clearance capacity X target concentration
257
Half life =
0.693(Vd/CL) O.693/K K=elimination rate constant
258
Hit and run drugs/suicide inhibitors/irreversible inhibitors
``` MAO inhibitors Omeprazole (all PPI) Organophosphate Guanethidine Resrpine Aspirin ```
259
Activated charcol is
Physical antagonist
260
Protamine sulphate
Heparin antidote,chemical antagonist
261
Prostacyclin VS
Thromboxane A2 physiological antagonists
262
Propranolol(beta blocker)
Pharmacological antagonist
263
Drugresponse curve(DRC) of competitive antagonist
Right shift Vmax(response)—unchanged Km(dose)—increased
264
DRC of non competitive antagonist
Reduce alope of DRC Vmax reduced Km(diose)—unchanged
265
Inverse agonist @ H3 receptir
Tiprolisant
266
Inverse agoniat @CB1 receptor
Riminabant
267
Inverse agonist @GABA-a
Beta carboline
268
Thalidomide teratogenicitu cause
Phocomelia
269
Lithium cause
Enstein anomaly(cardiac malformation)
270
ACE inhibitors cause
Renal agenesia
271
Warfrain cause
Chondrodyaplasia punctata
272
Carbimazole teratogenicity
Aplasia cutis
273
Tetracycline teratogenicitu
Bine teeth and cartillage defect
274
Valproate,methotrexate
Apina bigida(NTD)
275
Phenytoin teratogenicity
Cleft lip/palate
276
Z techinque
Intramuscular injections To avoid staining of aubcutaneous tissue Eg::anti paychotics,iron,DMPA
277
Essential drug
Satisfy priority healthcare needs of majority of population should not be combined with other drugs
278
Placebo
Dummy drug(no active ingredient)
279
Orphan drugs
Drug for rare disease(<1 per lakh population)
280
Schedule H drugs
Prescription drugs
281
Schedule G drug
Given under medical supervision
282
Schedule X drug
Narcotic and paychotrophic drugs(ketamine)
283
Phase zero trial
Micro dosing trial
284
Pharmacovigilance
Monitor adverse drug reactions
285
Disulfiram like reaction
1)Chlorpropamide,cefaperazone—methyk-thio-tetrazole(MTT) ring 2)gresiofulvin Metronidazole Procarbazine
286
Drugs undergoing acrtylation
``` SHIP—D Sufonamide Hydralazine Isonizid Procqinamide Dapsone ```
287
Drug frim Cinchona bark
Quinine
288
Drug from papaver somnoferim
Morphine alkaloid
289
Drugs from bellaanoda
Atropine
290
Drug from erythroxyluk coca
Coacine
291
Digitalis-fox glove
Digoxin
292
Thwrapeutic index
Safety margin of drug | TI=TD50/ED50
293
Side effects of anticancer drugs
``` 1) Bone martow supresssion(not seen in asparaginase,bleomycin,chlorambucil,vincristine) 2) Mucosal ulcer—palifermine 3) Chemotherapy induced nausea vomiting ```
294
Secondary cancer caused by anticancer drugs
AML
295
Anticancer drug causing SIADH
Vincristine>Taxanes
296
Anticancer drug causing cerebellar toxicity
Cytarabine
297
Ototixic anticancer drug
Cuclophosphamide cisplatin
298
Most emitogenic anticancer drug
Ciaplatin
299
Anticancer drug causing pulmonary fibrosis
Bleomycin | Busulphan
300
Anticancer drug causing cardio toxicity
Doxorubicin/adriamycin(anthracycline)
301
Nephrotoxic anticancer drug
Cisplatin | Antidote—amifostine
302
Anticancer causing henorrhagic cystitia
Cyclophosphamide,ifosfamide | MESNA
303
Anticamcer drug causing glove stock neuropathy
Paclitaxel
304
Anticqncer causing foot drop neuropathy
Vincristine
305
Anticancer drug causing hepatic vein fibrosis
Busulphan(budd chiari ayndrome) | Mx defibritide
306
Anticancer drig contrindicated in criggler najjar syndromw
Irinotecan
307
Anticancer drug causing flagellate pigmentaion
Bleomycin
308
Anticancer drig causing icthyosis
Bleomycin
309
Regimen for hodgkins lymphoma
``` ABVD Adriamycin Bleomycin Vinbastine Dacarbazine ``` ``` Earlier MOPP regimen Mechlorethamine Oncovin(vincristine) Procarbazine Prednisolone ```
310
Regimen of choice for CLL
FCR Fludarabine Cyclophosphamide Rituximab
311
Regimen of choice for AML
7 C 3D regimen | Cytarabine+Daunorubicin
312
Doc for hiatiocytosis,hairy cell leukemia
Cladribine
313
Regimwn for ALL
``` VPAD Vincristine Prednisolone Asparaginase Daunorubicin ```
314
Regimen for retinoblastoma
VEC Vincristine Etoposisde Carboplatin
315
Regimen for NHL
``` R—CHOP Rituximab Cyclophosphamide Hydroxy daunorubicin Oncovin Prednisolone ```
316
Regimen for colorectal cancer
FOLFOX/FOLFIRI+BEVCIZUMAB Follinic acide 5-FU oxiplatin/irinitecan
317
Regimen for acute promylocytuc leukemia
ATRA | Arsenic trioxide
318
Non small cell cancer mitation
Egfr
319
Maligannat melanoma drugs
1)BRAF inhibitors Vemurafenib,dabrafenib 2)MEK inhibitors Tremetinib,cobemetinib
320
Which cacineurin inhibitir cause gum hyoertrophy and hirsuitiam
Cyclosporin
321
Ises of thalidomide
Type 2 leprae reaction Mds Muriple myelima Oral ulcer
322
Most dangerous side effect of thalidomide
Neurotoxicity
323
Doc for endotracheal stenosis
Mitimycin c
324
Samptars triad
Aspirin+asthma*ethnoidal polyp
325
Aspirin in children cause
Reye’s syndrome hepatic failure
326
Fulminant hepatic failure in p mol
200 microgram /ml at 4 h and 30 micrigram at 15 hour
327
Monitoring of p mol ovedose
Rumack mathew nomogram
328
All cell wall inhibitor drugs are bacteriocidal except
Cycloserine bacteriostatic
329
Mmm cephalosporin causing disufiram raction,hypofibrenimia,and renal safe
Cefoperazone
330
Side effect of chloramphenicol
Grey baby syndrome | Aplastic anaemia
331
Vanvomycin side effects
Res man syndrome(histamine release)
332
A
333
Rate of drug eliminatoon
Plasma concentaration X clearance
334
Drugs follow zero order kinetics
``` Alcohol Theophylline Tolbutqmadime Heparin Phenytoin Methanol Warfarin ```
335
Loop diuretic ci with
Amino glycosides | Both cause ototoxicity
336
Doc for gtcs myoclonic seizure absence siezure
Valproate
337
Doc for partial seizure rolandic epilepsy
Carbamazepine
338
Seizures in neonate doc
Phenobarbital
339
Doc alcohol withdrawl seizures benzodiazepines
340
Status epilepticus
Lorazepam>>diazep
341
Infantile spasm with tuberous sclerosis
Vigabatri
342
Infantile spasm without tuberous sclerosiis
Acth
343
Trigeminal neuralgia
Carbamazepine
344
Restless leg syndrome prsmipexole
345
Antimicrobial causing seizures
Imipenenm Acuclovirflutoquinilone Cycloserine
346
Retinopathy
Cholroquine bulls eye retinopathy
347
Drugs causing qt prolongation
Eruthromycin Flq Quknines Bedaquinoine
348
Nephroticicity
``` Aminoglycosides Tetracycline Colistin Amphortericin b Sulfonamide Tenofocir avuclovir ```
349
Ototoxicity
Aminoglycoside Streptocycimi Minicyclin

Pharmacology (1 decks)

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