Dyspnea and Cough (Tyler) Flashcards

1
Q

What is the etiology of Churg-Strauss?

A

Idiopathic

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2
Q

What lab is important for dx GPA/WG?

A

c-ANCA

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3
Q

What might you include in the ddx for an acute cough?

A
URI or post-viral cough
Pneumonia
Pulmonary edema
PE
Aspiration pneumonia
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4
Q

What is the hallmark CXR finding in sarcoidosis?

A

Hilar adenopathy

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5
Q

Who usually presents with idiopathic pulmonary fibrosis?

A

Men in their 6th and 7th decades, current and past smokers

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6
Q

What diagnostic triad do we see in GPA (WG)?

A

URI, LRI, glomerulonephritis

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7
Q

What is the hallmark feature of idiopathic pulmonary fibrosis?

A

Heterogenous distribution of parenchymal fibrosis against background of mild inflammation (UIP)

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8
Q

What is idiopathic pulmonary fibrosis clinically characterized by?

A

Progressive parenchymal scarring and loss of pulmonary function

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9
Q

What extra pulmonary manifestations do we see with idiopathic pulmonary fibrosis?

A

Clubbing and right heart failure

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10
Q

What do we see in an CXR with idiopathic pulmonary fibrosis?

A

Bilateral reticular opacities

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11
Q

What might you include in the ddx for dyspnea?

A
Pneumonia
COPD
Asthma
Pneumothorax
Pulmonary emboli
Cardiac disease (i.e. HF, AMI, valvular dysfunction)
Difffuse alveolar hemorrhage
Metabolic acidosis
Cyanide toxicity
Interstitial lung disease
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12
Q

Are the granulomas in GPA/WG caseating?

A

Yes

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13
Q

What might you include in the ddx for a non-pulmonary cough?

A
GERD
Postnasal drip
Sinusitis
HF
Laryngitis
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14
Q

Who does GPA/WG usually present in?

A

30-50YO

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15
Q

What is the gold standard for idiopathic pulmonary fibrosis dx?

A

Lung biopsy

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16
Q

What are the three most common causes of dyspnea?

A

Heart disease
Lung disease
Anemia

17
Q

What might you include in the ddx for a chronic cough?

A

Post-nasal drip*
Asthma*
GERD*
Pulmonary infection*

Bronchiectasis, bronchitis, TB, CF, MAC, asthma, COPD, ACEi, environmental exposures, sarcoidosis, b-blockers

18
Q

What is the only tx shown to prolong survival in idiopathic pulmonary fibrosis?

A

Lung transplant

19
Q

What is the etiology of sarcoidosis?

A

Unknown

20
Q

Which vasculitides do we see sx of asthma and marked peripheral eosinophilia?

A

Churg-Strauss

21
Q

Are the granulomas in sarcoidosis caseating?

A

No

22
Q

Which vasculitides affects multiple organ systems, most common the skin and lungs?

A

Chung Strauss

23
Q

What is the most prominent sx seen in idiopathic pulmonary fibrosis?

A

Progressive dyspnea