E1 Flashcards
(44 cards)
Which of the following immunoglobulins is most efficient at causing direct hemmagluitnation?
- IgG
- IgM
- IgA
- IgE
IgM
What reaction grade would occur if compliment was activated?
- 4+ at room temperature
- 3+ at AHG
- Hemolysis
- Negative
Hemolysis
Some blood group antibodies may react stronger with the red cells of individuals who have inherited 2 identical alleles for the antigen to which the antibody is directed. This is known as:
- Post Zone effect
- Pro Zone effect
- Equivalence effect
- Dosage
Dosage
Patient plasma with donor rd cells produced an agglutination reaction of 1+. How do you interpret this?
- The reaction is weak, the patient can probably tolerate the donor cells.
- The donor blood is compatible with patient plasma
- The donor plasma is compatible with patient blood
- The donor blood is incompatible with patient plasma
The donor blood is incompatible with patient plasma
Which of the following occurs during storage of red blood cells?
- pH decreases
- 2, 3 DPG increases
- ATP increases
- Plasma K+ decreases
pH decreases
Which additive solution increases shelf life the longest, to 42 days?
- ACD-A
- CPDA-1
- CD2D
- AS-3
AS-3
A nurse just called to add on a cross match to a pretransfusion specimen you worked on 4 days ago. What is the most appropriate course of action?
- Check to see if there is enough volume in the original sample to complete the workup.
- Perform compatibility testing on the original specimen
- Indicate to the nurse that a new specimen need to be collected
- Repeat the type and screen testing on the original sample to see if the patient has made any antibodies after transfusion.
Indicate to the nurse that a new specimen needs to be collected for pretransfusion testing.
What test that you have learned counts as phenotype testing?
- ABO
- Antibody Screen
- IAT
- Polymerase Chain Reaction
ABO
The immunodominant sugar responsible for blood group A specificity is:
- Fucose
- N-acetyl galactosamine
- D-Galactose
- N-acetyl glucosamine
N-acetyl galactosamine
What property makes the ABO system the most significant for transfusion compatibility?
- Antibody ability to fix complement
- Low Distribution of antigen throughout the body
- Antibody is usually IgG
- All of the above
Antibody ability to fix complement
Which of the following statements is false?
- An individual with the BO genotype is homozygous for B antigen
- An individual with BB genotype is homozygous for B antigen
- An individual with OO genotype is homozygous for O antigen
- An individual with the AB phenotype is heterozygous for A and B antigens
An individual with the BO genotype is homozygous for B antigen
A mother is blood type O and a father is AB, what is the predicted percentage of offspring they would have that are blood type O?
- 0
- 25
- 50
- 100
0
A child is blood type as A, their biological sibling is O, their mother is blood type B, what is the father’s genotype?
- OO
- BO
- AO
- AB
AO
Anti-A: 4+
Anti-B: 0
Anti-D: 4+
A1 cell: 0
B cell: 0
Blood type: A pos
Assuming the interpretation is correct, Which result is in error?
- Anti-A
- Anti-B
- Anti-D
- A1 cell
- B cell
B cell
What is the blood type of the patient with the following serological reactions?
Anti-A: 0
Anti-B: 0
Control: 0
A1 cell: 4+
B cell: 4+
- AB
- A
-B - O
O
What is the most likely blood type of the patient with the following serological reactions?
Anti-A: 0
Anti-B: 2+ mf
Anti-A,B: 2+ mf
A1 cell: 4+
B cell: 0
- A2
- B3
- Bx
- Am
B3
Which of the following would NOT be a reasonable interpretation for these serological results.
Anti-A: 4+
Anti-B: 3+
Anti-A,B: 4+
A1 cell: 2+
B cell: 4+
- A1B with anti-I
- A2B with anti-A1
- AB2 with anti-B1
- O with cold agglutination
AB2 with anti-B1
—
B2 does not exist
Anti-A1 lectin is QC’d every day of use. It is used today, what two reagents are the best choice for positives and negatives controls?
- A1 cells and B cells
- B cells and O cells
- Anti-A and anti-B
- A1 cells and A2 cells
A1 cells and A2 cells
Which of the following ABO groups contains the least amount of H substance?
- A1
- A2
- B
- O
A1
O > A2 > B > A2B > A1 > A1B
Which blood type results would you see for a Bombay patient?
Becky: anti-A: 4+, anti-B: 4+, anti-D: 4+, A1 cell: 0, B cell: 0
Simone: anti-A: 4+, anti-B: 0, anti-D: 4+, A1 cell: 0, B cell: 4+
Carla: anti-A: 0, anti-B: 0, anti-D: 4+, A1 cell: 4+, B cell: 4+
Phi: anti-A: 0, anti-B: 0, anti-D: 0, A1 cell: 0, B cell: 0
-Becky
-Simone
-Carla
-Phi
Carla
—
Carla is O pos
A patient with hh, LeLe, sese, A genes will express what antigens on their red cells?
- A, H, Lea
- Lea only
- A and H only
- A, H, Lea, Leb
Lea only
—-
In order for it to be H it has to be capitalized HH
In order for it to be Lea and Leb, it has to be LeLe and SeSe or LeSe
What is the Rh blood group named for?
- its function on the cell
- the scientist who discovered it
- its position in the alphabet
- a monkey
a monkey
Which of the following is the most common Rh genotype in Asians?
- Dce/dce
- DCe/DCe
- DcE/dce
- DCe/dce
DCe/DCe
—
R1/R1 —> Laura’s explanation: just remember that the number one race car driver is an alpha romero. The really explanation is that 70% of asians are Dce.
(Choose all that apply) Which Rh system antibodies can an R0R0 patient make if they are immunized?
- anti-D
- anti-C
- anti-E
- anti-e
- anti-c
- anti-d
anti-C and anti-E
—
R0R0 —> Dce/Dce: Laura’s explanation. Since the patient is Dce/Dce, that means that they are only familiar with little c and little e. If they are immunized, they will make antibodies against what they don’t have, which would be anti-C and anti-E.
