E1Trans2 Flashcards

(60 cards)

0
Q

Analysis of similarities and differences in development, provides insight that ontogeny recapitulates phylogeny

A

Comparative embryology

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1
Q

Accounts on the processes and sequential events of development, step by step account

A

Descriptive embryology

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2
Q

State the Recapitulation Theory

A

The development of an individual organism summarizes the development of its species. Ontogeny recaps phylogeny.

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3
Q

Von Baer’s law

A

General features appear earlier in development while specific features appear later.

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4
Q

Stage wherein different species appear almost identical

A

Phylotypic stage (stage 1)

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5
Q

Oviparous

A

Eggs develop outside mother

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6
Q

Viviparous

A

Embryo develops inside mother

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7
Q

Ovoviviparous

A

Eggs retained in mother’s body until birth

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8
Q

Causative factors in development, testing hypotheses by manipulating embryo

A

Experimental embryology

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9
Q

Pioneer of experimental embryology

A

Wilhelm Roux

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10
Q

Studies problems on conception and contraception

A

Reproductive biology

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11
Q

Emphasis of reproductive biology

A
Normal gametogenesis
Transport of gametes and fertilization
Reproductive endocrinology
Early embryonic development
Transplantation of mammalian embryo
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12
Q

Study of interaction chemical and physical events in development

A

Chemical embryology

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13
Q

Study of birth defects, malformations due to endogenous and exogenous factors

A

Teratology

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14
Q

Main stages in histological development

A

Proliferation, migration, differentiation

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15
Q

Genetic defects in teratology

A

Mutations, aneuploidy, translocation

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16
Q

Fetal alcohol syndrome

A

Malformations due to lack of cell proliferation

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17
Q

Phocomelia

A

Severely deficient or malformed limbs due to genetic inheritance, mutations, or thalidomide

Phoco - seal, melia- limb

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18
Q

Who cloned Dolly? Where?

A

Ian Wilmut and Keith Campbell at the Roslin Institute

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19
Q

The process of creating genetically identical animals

A

Animal cloning

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20
Q

Posed the question “how are different parts of a developing embryo formed?”

A

Aristotle

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21
Q

Defined preformation

A

Aristotle

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22
Q

What is preformation?

A

A miniature embryo is enclosed in the germ cell and requires only time and nourishment for it to develop.

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23
Q

What is epigenesis?

A

The gradual formation of new structures and organs. From a single cell arises a multicellular organism.

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24
Spermists believe that...
Sperm cell contains an individual, ovum merely nourishes it
25
A tiny human (____) in fetal position at head of sperm
Encasement concept, homunculus
26
Ovists believe that...
Ovum contains the fetus, stimulated to grow by seminal fluid
27
Who strengthened the ovist belief? How?
Charles Bonnet, upon discovering parthenogenesis in insects
28
First to see human sperms with microscope
Anton van Leeuwenhoek and Louis Hamm
29
Studied structure of relatively advanced fetuses
Galen
30
Restrictions of Galen's study
Prevented serious analysis of early embryonic development due to miniature dimensions of embryo
31
Founder of modern reproductive biology
Reignier de Graaf
32
Described ovarian follicles and fallopian tubes, studied ectopic pregnancy
Reigniet de Graaf
33
Lazzaro Spallanzani believed that
Male and female sex products are necessary to initiate development
34
What did Marcello Malphigi do?
Described accurately the development of chick in egg.
35
Developed modern comparative embryology
Karl Ernst von Baer
36
Germ Layer theory was proposed by:
Karl Ernst von Baer
37
State the Germ Layer Theory
There exists three germ layers from which organs are derived.
38
"Embryo development occurs through progressive remodeling and growth."
Caspar Friedrich Wolff
39
Developed the cell theory
Matthias Schleiden, Theodor Schwann, and Rudolf Virchow
40
Implications of the Cell Theory
Embryology became a bona fide science, proved that development must occur via epigenesis
41
Theorized that development must follow a mosaic pattern
August Weismann
42
State the Germ Plasm Theory. Who proposed it?
Differentiated the somatic and germ cells, August Weismann
43
Function of somatic cells according to Germ Plasm Theory.
For the protection and proliferation of the germ plasm.
44
Function of germ cells according to Germ Plasm Theory.
For perpetuation of the species.
45
Other name for Mosaic Development
Weismann's Theory of Nuclear Determination
46
Why is the Mosaic Model called as such?
Egg is considered a mosaic of discrete localized determinants.
47
Describe Mosaic development.
Nuclei contain factors that ate asymmetrically distributed in daughter cells, fate of each cell is predetermined.
48
What experiment did Roux perform?
Ablation Experiment or Embryonic Extirpation
49
Removed large pieces from eggs and discovered that any single monad was capable of forming any part of the completed embryo.
Hans Adolf Eduard Driesch
50
Consequence of Driesch's experiment.
Led to the terms pluripotent and totipotent.
51
Describe regulative development.
Ability of the embryo to develop even if some cells are removed or rearranged.
52
Who performed the Induction and Transplantation experiments?
Hans Spemann and Hilde Mangold.
53
What is the organizer/evocator?
Dorsal lip of blastopore.
54
Distinguished between phenotype and genotype.
Wilhelm Johanssen
55
Describe the relationship between genotype and phenotype.
Genes are manifested through phenotype only upon the activation depending on time and space.
56
Worked on mutant genes and discovered genes encoded proteins.
Salome Glueksohn-Waelsch and Conrad Waddington
57
Unified science of embryology and genetics.
Developmental Genetics
58
Coined epigenetics.
Conrad Waddington
59
Epigenetics states that
The development of an embryo is due to a series of causal interactions between parts. It accounts for the development of an embryo and reminds one that genetic factors are the most important determinants of development.