Ectoparasites Flashcards

1
Q

What are ectoparasites? And some common ones?

A

Ectoparasites are organisms that live on or in skin or outgrowths of skin or another organism.

  • Lice / pediculosis
  • Scabies
  • Cutaneous larva migrans
  • Myiasis – fly larve
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2
Q

What are the three types of lice?

A

Lice are highly specialised blood sucking parasites that live on a single host species.

The head louse – pediculus humanus capitus

Public louse – Phthirus pubis

Body louse – pediculus humanus corporis

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3
Q

What is the life cycle of lice?

A

Starts as egg on hair, nit

Egg hatches, goes through various stages before becoming male or female adult

Takes about 10 days from nymph stage to egg laying female

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4
Q

Epidemiology of lice

A

Head lice
- Ubiquitous in school kids

Body lice
- Poverty and poor hygiene
- Homeless, refugees

Pubic lice
- Sexual contact

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5
Q

Head lice symptoms

A

Symptoms include itching of scalp, neck, behind ears

Common in children

Transmission direct head to head contact or sharing hair stuff

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6
Q

Body lice symptoms

A

Body lice (pediculus humanus corporis)

Symptoms: itching, bite marks on body

Most common in communities dealing with poverty, overcrowding and poor personal hygiene

Transmission: body lice living in clothing and affect the body

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7
Q

Pubic lice symptoms

A

Public lice (pthirus pubis)

Symptoms: itching of the pubic area, bluish colored sore

Transmission: direct sexual contact, not spread by toilet seats

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8
Q

Complications of lice

A

Secondary bacterial infections e.g impetigo

Allergic reactions to louse saliva

Body lice are vectors to infectious diseases – epidemic typhus (Rickettsia prowazekii), Trench fever (Bartonella quintana), louse-borne relapsing fever (borrelia recurrentis)

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9
Q

Diagnosis of lice

A

Clinical inspection of affected areas
- Head
- Body and clothes
- Pubic area

Combing with louse comb for nits

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10
Q

Treatment of lice

A

Transmission is through close hair to hair, skin to skin or sexual contact

Treatment recommended for those with active infection and close contacts with tropical pediculicides
- Standard treatment pyrethrin shampoo or lotion 1%
- Other lotions: benzyl alcohol 5%, ivermectin 0.5% and malathion 0.5%

Treatment should be repeated after 9-10 days because treatment doesnt affect nits, have to wait for nits to hatch

Overall ivermectin (single dose 100ug/kg) repeated after 9-10 days

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11
Q

Treatment of body lice

A

Machine wash all washable clothing and bed linens that the infected person touched during the two days before treatment to kill lice and nits. Use hot water cycle (130 F/ 55 C) to wash clothes. Dry laundry using hot cycle for at least 20 mins

Fumigation or dusting with chemical insecticides sometimes is necessary to control and prevent the spread of body lice for certain diseases (epidemic typhus)

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12
Q

What is scabies?

A

A mite caused by sarcoptes scabiei var hominis

  • Female lays eggs
  • Egg develop into larva, nymph and then adult female
  • Adult female creates burrow under skin where it lays eggs
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13
Q

Epidemiology of scabies

A

Ubiquitous geographic distribution - common in latin america, china, southeast asia, indonesia

Transmission requires prolonged skin to skin contact

Higher prevalence in conditions of poverty
- Infants
- Homeless
- Refugees
- Inhabitants of poor neighbourhoods

Sexual transmission

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14
Q

Clinical presentation of scabies

A

Intense pruritus (itching), especially at night

Papular rash (pimple like)

Scales or blisters

Track like burrows, raise where female lays 10-25 eggs

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15
Q

Scabies complications

A

Sleep disturbances due to itching, can cause economic impact

Crusted scabies

Secondary infections like impetigo that can cause local skin infections, septicaemia sig fatality rate, glomerulonephritis, rheumatic fever

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16
Q

Diagnosis of scabies

A

Clinical presentation looking for burros

Skin scraping – identification of mites

17
Q

Treatment of scabies

A

Permethrin cream 5%

Malathion 0.5% cream

Topical creams e.g permethrin cream
if that fails use malathion 0.5% lotion

Cream/lotion applied to whole body from neck down and left 20hrs and then washed off – repeated after 7 days

Treat all household and sexual contacts

Oral ivermectin (200ug/kg) repeated after 2 weeks because not ovicidal – highly effective as community or mass treatment

18
Q

What is cutaneous larva migrans / creeping eruption / ground itch caused by?

A

Zoonotic hookworm larvae - Ancylostoma braziliense, A.caninum, A.ceylanicum

19
Q

Epidemiology of cutaneous larva migrans

A

Common in tropical and subtropical regions

Only sporadically in temperate regions

Affects small children, inhabitants of poor neighbourhoods, travellers to tropical regions

20
Q

Clinical presentation of cutaneous larva migrans

A

Tracks of larvae moving around skin, leaves proteins in wake that have inflammatory reaction.

Diagnosis by clinical presentation.

21
Q

Treatment of cutaneous larva migrans

A

Do not survive more than 5-6 weeks in human host

Often resolves without treatment

Treatment recommended to prevent secondary bacterial infections:

  • Topical thiabendazole 5-15%
  • Oral albendazole 400mg for 3 days
  • Oral ivermectin (200ug/kg) single dose
22
Q

Tungiasis

A

Also known as jiggers, nigua, sand fleas

Caused by tunga penetrans that parasitizes pigs, dogs and bovines

Fertilised female digs into skin, gradually becomes bigger and more pacted with eggs and causes pain as it gets bigger

23
Q

Epidemiology of tungiasis

A

Infestation of dogs, cats, pigs, cows and peri domestic rodents

Latin america, carribean, sub-saharan africa

Affects inhabitants of poor neighbourhoods or rural villages

Rarely travellers

24
Q

Clinical presentation of tungiasis

A

Impacted female inside skin

Can be removed with forceps or needles

Can cause a lot of pain, severe and incapacitating

diagnosis by examination of typical lesion

25
Q

Complications of tungiasis

A

If embedded sand-fleas are not extracted soon after penetration, superinfection may ensue

Bacterial infections

Abscesses, suppuration and lymphangitis
- Lymphoedema
- Post-streptococcal glomerulonephritis
- Tetanus
- Septicaemia/gangrene
- Disability

26
Q

Treatment and control of tungiasis

A

Removal of embedded flea with sterile needle

More extensive infestations require surgical extraction under sterile conditions

Immersion up to ankle for 10 mins with 0.005% potassium permanganate or dimeticones of low viscosity

prevention by use of repellents and one health approach

26
Q

Treatment and control of tungiasis

A

Removal of embedded flea with sterile needle

More extensive infestations require surgical extraction under sterile conditions

Immersion up to ankle for 10 mins with 0.005% potassium permanganate or dimeticones of low viscosity

prevention by use of repellents and one health approach

27
Q

Myiasis

A

Caused by botfly larvae of various species

Most common are dermatobia hominis that causes furnucular lesions and cochliomyia hominivoraz that causes screwworm

28
Q

Myiasis lifecycle

A

Catches mosquito, lays eggs on mosquito

Mosquito finds warm blooded vertebrae, larvae hatch from eggs and invade skin

Or botfly can lay eggs directly on human skin

Larvae develop inside skin and eventually drop out of skin and form pupa in soil to later develop into adult fly

29
Q

Epidemiology and clinical presentaion of myiasis

A

tropical and subtropical regions, ecuador

Larvae in skin, pops head out, may form abscess
Spines on body so can’t be squeezed out
Fly can lay eggs on open wound which can become infested, associated with mortality, screwworm infestation

Screwworm can live in ears, palate

30
Q

Complications of myiasis

A

Dermatobia hominis
- Secondary infections may occur after extraction
- Lesions, particularly when multiple are painful and alarming

Screwworm
- Disability
- Secondary infections
- Death

diagnosis by clinical presentation and larval extraction and identification of larvae

31
Q

Treatment of myiasis

A

Dermatobia hominis
- Occlusion with Vaseline
- Surgical excision
- Oral ivermectin (200ug/kg) single dose

Screwworm
- Surgical extraction with debridement of dead tissue
- Oral ivermectin
- Antibiotics

Control/prevention
- One health approach
- Insect repellents/mosquito nets

32
Q

Treatment of myiasis

A

Dermatobia hominis
- Occlusion with Vaseline
- Surgical excision
- Oral ivermectin (200ug/kg) single dose

Screwworm
- Surgical extraction with debridement of dead tissue
- Oral ivermectin
- Antibiotics

Control/prevention
- One health approach
- Insect repellents/mosquito nets