EEG And ICP Monitoring Flashcards

1
Q

How much energy does the cerebrum require?

A

3-5 ml O2/min/100g tissue

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2
Q

Normal Cerebral Blood Flow is ___.

A

50 ml/min/100 g tissue 750 ml/min for brain Delivers 150 ml O2/min

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3
Q

O2 extraction from cerebral blood flow is:

A

35-50%

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4
Q

What is the equation for Cerebral Perfusion Pressure (CPP)?

A

CPP = MAP - ICP

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5
Q

Cerebral blood flow is:

A
  • Tightly regulated except post-trauma
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6
Q

Cerebral blood flow stays around ____, as long as MAP is between _____ mm Hg.

A

50 ml/100g/min , 50-100

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7
Q

CBF is reduced by

A
  1. Head injury 2. Intracranial hypertension 3. Hypotension 4. Hyperventilation 5. Vasospasm
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8
Q

Ways of directly monitoring ICP:

A
  1. Ventricular catheters 2. Subdural/subarachnoid bolts 3. Epidural transducers 4. Intraparenchymal fiber optic devices
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9
Q

What is the Monroe-Kellie hypothesis:

A

The skull is a fixed volume. If one or more of these components increases, ICP rises: - Blood - CSF - Brain

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10
Q

ICP determined by:

A
  • Brain mass (80%) - Blood flow (10%) - CSF volume (10%)
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11
Q

ICP monitoring physical set up

A
  1. Connection of device to transducer 2. Watertight fluid interface 3. Deformation of transducer membrane converted to electrical pulsations and amplified and displayed as a waverform
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12
Q

Zeroing of ICP Monitors requires:

A
  • Zeroing to room air - Catheter tip transducers only zeroed prior to insertion - External transducers can be zeroed anytime
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13
Q

Indication for ICP monitoring:

A

-GCS < 8 (or higher if CT of concern {Hematoma, Edema, Contussion, etc}) -Normal CT with GCS 40 2. Posturing 3. SBP < 90 mm Hg -Sedation precluding clinical assessment

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14
Q

ICP monitoring is useful in:

A
  1. Head injury 2. Poor grade SAH 3. Intracerebral hematoma 4. Meningitis 5. Stroke 6. Allows calculation of CPP 7. Info on intracerebral compliance
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15
Q

ICP Values:

A

Normal: 7-15 mm Hg Abnormal: > 20 mm Hg If > 25 mm Hg, aggressive management indicated

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16
Q

High ICP:

A

will cause internal or external herniation of the brain, distortion and pressure on cranial nerves and vital neurological centers

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17
Q

When ICP is elevated cerebral perfusion will be:

A

Impeded and operating conditions difficult or impossible

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18
Q

When brain volume increases

A

loss of CSF and reduction of venous blood volume act to compensate

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19
Q

Subdural hematoma can lead to:

A

Tentorial herniation

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20
Q

Hemorrhage can lead to:

A

Subfalcine herniation

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21
Q

Devices to measure ICP:

22
Q

What is the Gold Standard of ICP measuring?

A

Intraventricular drain and transducer b/c you can control ICP by CSF drainage and zero externally

23
Q

What are the contraindications of intraventricular drain and transducer?

A
  • Bleeding
  • Blockage
  • Infection risk
  • Insertion difficulties
24
Q

Which ventricle is the intraventricular catheter placed?

A

Lateral ventricle (frontal horn)

25
What are the positive points of the intraparenchymal pressure monitor?
- Lower infection risk - Less risk of hermorrage - Excellent metrological properties (less drift)
26
What are the negatives to a intraparenchymal pressure monitor?
- Underestimate very high ICP - Drift a problem after several days
27
What are the contraindications of intraparenchymal pressure monitors?
- Intracranial infection - Coagulopathies - Severe skull fractures - Conditions where CFS drainage is necessary
28
Phase 1 of the ICP Waveform:
P1: Percussion wave (arterial pulsation)
29
Phase 2 of ICP waveform:
P2: Rebound wave (Intracranial compliance)
30
Phase 3 of ICP waveform:
P3: Dichrotic wave (venous pulsations)
31
ICP Management: Decrease brain water w/
* hyperosmolar diuretics (Mannitol w/ intact BBB 0.25 - 1 g/kg) * Loop diuretics (Lasix) * Corticosteroids
32
ICP Management: Reduce CSF Volume by:
* Drainage (Ventricular, lumbar subarachnoid, head elevation)
33
Auto regulation is impaired by:
* Inhalational anesthetics * Direct acting vasodilators (Adenosine, Prostacyclin, Ca++ Channel blockers, NTG, Nitroprusside)
34
Transcranial Doppler (TCD) Ultrasonography:
* Allows CBF velocity measurement (continuous or intermittent) * Most usefule for vasospasm post subarachnoid hemorrhage * Vasospasm: increased flow velocity * Ratio of ICA:MCA flow allows monitoring independent of rising ICP
35
Continuous Electroencephalogram (EEG) Monitoring:
The summation and recording of postsynaptic potentials from the pyramidal cells of the cerebral cortex; reflects metabolic activity of the brain
36
EEG is a tracing:
Of voltage fluctuations versus time recorded from electrodes placed over scalp in specific array; represent fluctuating dendritic potentials from superficial cortical layers;
37
Disadvantages of EEG:
* Required Amplification * Deep parts of the brain are not well sampled * Detects cortical dysfunction but rarely discloses its etiology * Relatively low sensitivty and specificty * Subject to electrical and physiological artifacts * Influenced by state of alertness, hypoglycemia, drugs * Small or deep lesions might not produce an EEG abnormality * Limited time sampling and spatial sampling
38
Placement of EEG Electrodes:
* Usually 21 or more * Spaced at 10 or 20% of distances btwn specified anatomic landmarks * Odd # of electrodes over left, even over right
39
Indication for EEG:
* Craniotomy for cerebral aneurysm clipping when a temporary clip is used * Carotid Endarterectomy (under GA) * Cardiopulmonary bypass * Extra cranial-intracranial bypass procedures * Pharmacologic depression of brain for "cerebral protection"
40
EEG Waveforms: Beta
13 - 30 Hz; Awake and alert (short and frequent)
41
EEG Waveforms: Alpha
8-13 Hz; closed eyes, relaxed (Tall and frequent)
42
EEG Waveforms: Theta
4-7 Hz Tall and infrequent (GA)
43
EEG Waveforms: Delta
0-4 Hz, Deep sleep, deep sedation (Very tall and very infrequent)
44
EEG Artifacts
* Eye-induced artifacts (includes eye blinks and eye mvmt) * Gloss kinetic artifacts * Poor grounding * IV drips * Body mvmt * EKG artifact
45
EEG Monitors: Continuous Electroencephalography
* BIS algorithm * Snap * State entropy/Respone entropy (Datex-Ohmeda algorithm) * SEDLine monitor (Patient state analyzer) * A-Line AEP Monitor/2 (EEG plus AEP) and Cerebral State Monitor (EEG Only) * EEG and Auditory Evoked Potentials * Narcotrend (EEG Monitor)
46
The EEG is NOT
A predictor of mvmt under GA
47
EEG Monitoring: Activation
High frequency, Low voltage; Light Anesthesia, Surgical stimulation
48
EEG Monitoring: Depression
Low frequency, high voltage; Deep anesthesia, cerebral compromise
49
Agents That Activate
* Subanesthetic inhalationals * Low dose barbiturates/benzodiazepines * Small doses of etomidate * N2O * Ketamine * Mild hypercapnia * Stimulation (surgical) * Early hypoxia
50
Agents That Depress
* 1-2 MAC gases * Barbiturates/propofol/etomidate * Narcotics- dose dependent * Hypocapnia * Hypothermia * Late hypoxia