Effects of Opioids. Flashcards

1
Q

CNS

A

analgesia, sedation, euphoria.

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2
Q

Respiratory

A
respiratory depression (⬆️CO2). 
Antitussive actions (suppression of cough reflex
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3
Q

GI

A

nausea, vomiting, constipation.

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4
Q

CVS

A

hypotension

bradycardia

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5
Q

Biliary tract

A

↑ biliary tract pressure ➡️ biliary colic

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6
Q

Renal

A

contraction of the smooth muscle of ureters and urinary bladder ➡️ increased ureteral and bladder sphincter tone.

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7
Q

Hormonal

A

↑ GH, prolactin and ↑ ADH leading to less urine produced (urine retention)

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8
Q

Eyes

A

Miosis

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9
Q

Histamine

A

Morphine releases histamine from mast cells causing urticaria, sweating, flushing, pruritus and vasodilation (Asthma !!!).

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10
Q

Effects that not cause tolerance

A

miosis

constipation.

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