Eivind Almaas - Systems Biology Flashcards

1
Q

Describe the three primary fundamental concepts in constraint-based reconstruction and analysis methods

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2
Q

Reason why optimization of biomass production is a reasonable objective when modeling microbes

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3
Q

Briefly discuss reasons for why the “simplistic” FBA method works so well in predicting cellular phenotypes

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4
Q

Is it possible to model genetic perturbations using COBRA methods? If yes, briefly explain how.

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5
Q

Briefly describe three limitations for current implementations of constraint-based modeling

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