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MBChB - Y5 - FINALS > El Drugo > Flashcards

El Drugo Flashcards

1
Q

Solifenacin

A

antimuscarinic for urge incontinence

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2
Q

Idarucizumab

A

a reversal agent for dabigatran

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3
Q

Andexanet alfa

A

reversal agent for apixaban and rivaroxaban

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4
Q

Name some dopamine agonists (3)

A

Ropinirole

Cabergoline

Bromocriptine

Apomorphine

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5
Q

What drug is used to increase arterieal resistance in the context of orthostatic hypotension seen in parkinsons?

A

Midodrine

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6
Q

What is used to manage the drooling of saliva seen in people with parkinsons?

A

Glycopyronium bromide

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7
Q

decarboxylase inhibitors (prevents peripheral metabolism of levodopa to dopamine)

A

Carbidopa

Benserazide

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8
Q

MAO-B inhibitor

A

Selegeline

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9
Q

COMT inhibitors

A

Entacapone

Tolcapone

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10
Q

Erythropoeitin replacememnt in chronic kidney failure?

A

Darbapoeitin alfa

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11
Q

Gonadotrophin releasing hormone agonists

A

Goserelin

Leuprolin

Degarelix

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12
Q

a drug utilised in anaesthesia for reversal of neuromuscular blockade caused by rocuronium and vecuronium

A

Sugammadex

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13
Q

Combination of levodopa and carbidopa

A

Sinemet

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14
Q

Combination of levodopa and benserazide

A

Madopar

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15
Q

Which drug can help people with muscular dystrophy (over 5 years of age and can walk)?

A

Ataluren

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16
Q

Which drug can help people with MS walk?

A

Fampridine

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17
Q

Which drug is used to treat muscle spasms in MS?

A

Baclofen

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18
Q

Which drug can help fatigue in MS?

A

Amantadine (NMDA antagonist)

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19
Q

Drug used to treat small bowel bacterial overgrowth syndrome

A

Rifaximin

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20
Q

What is used to confirm diagnosis of glandular fever?

A

Heterophil antibody test

(monospot test)

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21
Q

What drug can be used (antifibrotic) to help treat pulmonary fibrosis?

A

Pirfenidone

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22
Q

Treatment of threadworm

A

Mebendazole

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23
Q

Pegvisomant

A

GH receptor antagonist - prevents dimerization of the GH receptor

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24
Q

Alpha blocker used to stabilise patient with phaechromocytoma

A

Phenoxybenzamine

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25
Q

Treatment of hypoparathyroidism

A

Alfacalcidol

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26
Q

Tolvaptan

A

Used to treat polycycstic kidney disease one some patients

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27
Q

Flumezanil

A

Benzodiazepine overdose

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28
Q

Investiagtions for carcinoid tumours

A

Urinary 5-HIAA

Plasma chromogranin A y

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29
Q

Pentoxyphyline

A

Sometimes used in alcaholic hepatitis

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30
Q

Bortezomib

A

therapy for myeloma patients suitable for autologous stem cell transplant (used in conjunction with dexamethasone)

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31
Q

Treatment of lead poisoning?

A

dimercaptosuccinic acid (DMSA)

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32
Q

Filgrastim

A

G-CSF - used in neutropenia in select cases

33
Q

Treatment of multiple non-keratinized genital warts?

A

Podophylum

34
Q

Toxoplasmosis treatment

A

Pyrimehamine plus sulphadiazine

35
Q

Treatment of severe cases of pneumocystis jiroveci

A

Pentamidine

36
Q

Ethylene glycol poisoning treatment?

A

Fomepizole

37
Q

TNF alpha inhibitors

A

Adalimumab

Infliximab

Etanercept

38
Q

Bevacizumab

A

Anti-VEGF

Colorectal cancer

renal and glioblastoma

39
Q

Imatinib

A

Tyrosine kinase inhibitor

Used in GI stromal tumours and CML

40
Q

Basiliximab

A

IL2 binding site

Renal transplants

41
Q

Cetuximab

A

Epidermal growth factor inhibitor

(EGF positive colorectal cancers)

42
Q

Drug licensesd for use in peripheral arterial disease

A

naftidrofuryl oxalate: vasodilator, sometimes used for patients with a poor quality of life

43
Q

Anti-androgen - used to prevent rise in testosterone after starting goserelin

A

Cyproterone acetate

44
Q

Xanthine oxidase inhibitor

A

Febuxostat

45
Q

Pegloticase

A

(polyethylene glycol modified mammalian uricase) can achieve rapid control of hyperuricemia. It is given as an infusion once every two weeks.

46
Q

Folinic acid

A

Used in the treatment of methotrexate toxicity

47
Q

Demeclocycline

A

Reduces responsiveness of the collecting tubule cells to ADH - used to treat SiADH

48
Q

Treatment of restless leg syndrome

A

Ropinirole

49
Q

Treatment of idiopathic intracranial hypertension

A

Acetazolamide (diuretic)

50
Q

Treatment of myaesthenia gravis

A

Pyridostigmine

51
Q

The sensation of insects crawling on your skin

A

Formication

52
Q

Treatment of glaucoma (eye drops)

A

Pilocarpine (parasympathetic)

Timolol (beta blocker)

Apraclonidine (a-2 agonist)

53
Q

Management of severe cases of serotonin syndrome?

A

Cyproheptadine

Chlorpromazine

54
Q

Anticholinesterase inhibitors used to treat mild to moderate alzheimers disease

A

Donepezil

Galantamine

Rivastigmine

55
Q

Lithium induced nephrogenic DI

A

Amiloride

a potassium-sparing diuretic often used in conjunction with thiazide or loop diuretics. Amiloride also used for other causes of nephrogenic DI. Nephrogenic DI also treated with thiazide diuretics (chlortalidone and hydrochlorthiazide)

56
Q

Mouthwash or spray that is useful for treating the discomfort associated with a painful mouth that may occur at the end of life

A

Benzydamine hydrochloride

57
Q

Survival benefit in those with motor neurone disease?

A

Riluzole

58
Q

Management of neuroleptic malignant syndrome?

A

Dantrolene

Bromocriptine (this can also be used to manage hyperprolactinaemia)

59
Q

Management of athletes foot?

A

topical imidazole, undecenoate, or terbinafine first-line for athletes foot.

60
Q

Treatment of flushing but limited telangiectasia in acne rosacea?

A

Brimonidine gel

61
Q

Treatment of scabies

A

Permethrin

62
Q

Treatment of threadworms

A

Mebendazole

63
Q

Vasodilator used to treat venous ulcers

A

Pentoxifyline

64
Q

2nd Line ADHD treatment

A

If there is inadequate response, switch to lisdexamfetamine;

Dexamfetamine should be started in those who have benefited from lisdexamfetamine, but who can’t tolerate its side effects.

65
Q

Lichen sclerosus treatment

A

Topical clobetasol proprionate

Topical tacrolimus may be initiated by specialists

66
Q

Treatment of candida nail infection

A

Amorolfine

67
Q

Treatment of hyperhidrosis

A

Topical aluminium chloride preparations

68
Q

Monoclonal antibody used to prevent RSV in children that are at increased risk of severe disease

A

Palivizumab

69
Q

Treatment for dermatitis herpetiformis

A

Dapsone

70
Q

What should be used to treat impetigo if fusidic acid resistance is suspected?

A

Mupirocin

71
Q

What are early keloids treated with?

A

intra-lesional steroids e.g. triamcinolone

72
Q

Treatment of chronic plaque psoriasis

A

Topical betamethasone and topical calcipotriol

73
Q

treatment for actinic keratosis

A

5-fluorouracil and imiquimod

74
Q

Verucca treated with

A

Salicylic acid

75
Q

Second line treatment for hyperhidrosis (useful for patients with palmar, plantar and axillary hyperhidrosis)

A

Iontophoresis

Botox is useful for axillary symptoms

76
Q

Drug used to prevent attacks of menieres disease?

A

Betahistine

77
Q

Pizotifen

A

First line prophylaxis of migraines alongside propranolol

78
Q
A

MBChB - Y5 - FINALS (3 decks)

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