Elastography Flashcards

(43 cards)

1
Q

What does elastography measure?

A

Stiffness of the liver

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2
Q

What is used to measure the stiffness of a material?
(hint: the units)

A

Youngs Modulus in kPa

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3
Q

What unit is Young’s modulus measured in?

A

kPa

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4
Q

What is true of materials with a SMALL young’s modulus?

A

Softer material and a larger strain as it can compress more easily

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5
Q

What is true of materials with a LARGE young’s modulus?

A

Stiffer material and a small strain as it cannot compress very easily

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6
Q

What type of ultrasound technology is used for shear wave imaging?

A

Elastography

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7
Q

In shear wave imaging, how is the stiffness of liver quantified?

A

It is measured in kPa and a HIGHER score indicates a greater stiffness

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8
Q

What is the range in kPa for soft tissue?

A

1-300 kPa

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9
Q

What is the value in kPa for fat vs. fibrotic liver?

A

Fat = 1

Fibrotic liver = 300

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10
Q

What is the formula for Young’s modulus?

A

Force/strain

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11
Q

What is the ratio of the applied stress to the resulting strain a result of?

A

A stress that either compresses or stretches tissue - measured with Young’s modulus

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12
Q

Elastography provides an imaging means of?

A

Palpation

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13
Q

What method in elastography involves initiating a MANUAL force to the tissue?

A

STATIC

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14
Q

In using what method can Young’s modulus not be quantified and only uses qualitative information?

A

Static method

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15
Q

Applications of static elastography?

A
  1. Cancer detection of small parts (breast, thyroid, prostate)
  2. Myocardium viability
  3. Monitoring of therapies that alter tissue composition such as ablation
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16
Q

Dynamic methods use what kind of force?

A

Short transient force or time-varying repetitive force

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17
Q

What force is INITIALLY produced in a dynamic method?

A

Compressional strain

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18
Q

What is another term for compressional strain?

A

Transient or oscillatory

19
Q

Does compressional strain travel at a high or low propagation speed? What is the speed?

A

High: 1440-1640 m/s

20
Q

Through what kind of force is a compressional strain converted to shear waves?

A

Radiation force

21
Q

Do shear waves travel at a high or low propagation speed? What is the speed?

A

Low: 0.5-10 m/s

22
Q

In what direction do shear waves propagate in tissue during shear wave elastography?

A

Perpendicular to the direction of tissue compression

23
Q

How can shear displacements of propagating shear waves be tracked?

A

Ultrafast by using high frame rates to determine their propagation speed

24
Q

What does ARFI stand for?

A

Acoustic Radiation Force Impulse Imaging

25
What is the function of ARFI?
Determining propagation speed of tissue to determine the stiffness
26
How do we determine propagation speeds in shear wave imaging?
Using high frame rates
27
What units is shear wave reported in?
m/s
28
What kind of method is used to determine quantitative information?
Dynamic
29
Where do we scan for shear wave?
Intercostally
30
What segments of the liver are shear wave measurements taken from?
7 or 8
31
Take elastography measurements using what kind of breath on a patient?
Suspended breath hold
32
Where should the shear wave box be located?
1-2 cm below liver capsule
33
T or F? We should always increase the gain in shear wave imaging
FALSE: Do not attempt to increase the gain as it will likely lead to an inaccurate measurement
34
To have a good shear wave measurement, how much colour must be filled in?
>50%
35
F1 Normal to mild fibrosis staging in kPa?
5.48-8.29
36
F2 mild to moderate fibrosis staging in kPa?
8.29-9.4
37
F3 moderate to severe fibrosis staging in kPa?
9.4-11.9
38
F4 Cirrhosis
>11.9
39
What position is the patient usually in during elastrography?
Supine or LLD with R arm above head
40
What method uses both qualitative and quantitative assessment of liver stiffness?
Dynamic - no force applied
41
T or F? Radiation force is most intense at the focal zone?
TRUE
42
Radiation force is a result of a change in wave?
Momentum due to scattering at an obstacle
43
What is measured to equal radiation force?
Rate of momentum change, averaged over the period of the wave