Electrical Activity of the Heart Flashcards

1
Q

IK1 meaning. When do they open?

A

inward rectifying K + channels that are voltage gated channels that open at rest

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2
Q

How do inward Ca+ channels for phase 4 of nodal cells differ from L type Ca2+ channels?

A

open at a more negative membrane potential ~ -70 mV

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3
Q

What currents are responsible for phase 4 of nodal cell action potential?

A

inward Ca2+ current

Inward Na+ current If (funny current)

Outward K+ current

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4
Q

What is the S wave?

A

1st downward deflection after an R wave

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5
Q

What is PR interval?

A

start of the P wave to start of QRS complex

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6
Q

What is QT interval? What does it represent?

A

start of QRS complex to end of the T wave; represents duration of the AP

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7
Q

What is ST segment? What does it correspond to in the action of the cardiac myocytes AP?

A

End of S wave to beginning of T wave; ventricles are depolarized; corresponds to plateau phase of AP

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8
Q

What is J point?

A

end of the S wave; represents isoelectric point

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9
Q

What is the trick to being able to tell bpm (beats per minute) based off of boxes on ECG?

A

Count big boxes from R wave to R wave
1 = 300
2 = 150
3 = 100
4 = 75
5 = 60
6 = 50

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10
Q

What does one big box on the y axis (volts) on the ECG represent? (how many V)

A

0.5 mV

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11
Q

What does one big box on the x-axis of the ECG represent?

A

0.2 sec (200 msec)

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12
Q

What are the steps to reading an ECG?

A

Step 1: determine rate and rhythm

Step 2: Waves Examine the trace for the presence of P, QRS, and T can they be seen and do they look normal?

Step 3: PR interval and determine if it is in normal range about 120 - 200msec (3-5 small boxes). Look to see if PR is consistent

Step 4: Estimate the MEA (mean electrical axis)

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13
Q

What is the MEA?

A

indicates the net direction (vector) of current flow during ventricular depolarization. Each lead can be represented by an angle.

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14
Q

Be able to explain the quadrant method for determine MEA.

A
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15
Q

What are the causes of left axis deviation?

A
  • left heart enlargement, either left ventricular hypertrophy or dilation
  • conduction defects in the left ventricle, except in the posterior bundle branch
  • acute MI on rt. side tends to shift the axis left unless the rt ventricle dilates
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16
Q

What are causes of rt axis deviation?

A
  • right heart enlargement, hypertrophy or dilation
  • conduction defects of rt. ventricle or the posterior left bundle branch
  • acute MI on left side tends to shift the axis rt unless the left ventricle dilates
17
Q

What does the image here represent? Explain.

A

First degree heart block

Long PR interval (> 200 sec; one big box)
Slowed conduction through AV node
rate and rhythm typically normal here

18
Q

What pathology does this image represent? Explain.

A

Second degree heart block (Mobitz Type I )

In second degree, every QRS complex is preceded by a P wave, but not every P wave is preceded by QRS complex

Mobitz I (Wenckebach)
when there is progressive prolongation of PR interval until a ventricular beat is missed and then the cycle begins again.

This arrhythmia will have an unsteady rhythm

19
Q

Which condition is being seen here? Explain.

A

Second degree heart block Mobitz type II

In second degree, every QRS complex is preceded by a P wave, but not every P wave is preceded by QRS complex

PR interval is consistent (i.e it doesn’t lengthen this separates it from Wenckebach.)

Rhythm can be steady or unsteady

20
Q

Which conditions is being seen here? Explain.

A

complete heart block

complete dissociation of P waves and QRS complexes

Steady rhythm (usually)

Verrrrrrrrry slow rate

21
Q

Which condition is being seen here? Explain.

A

Atrial flutter

fast atrial rate,

“saw tooth” appearance of waves

no discernable T waves

rhythm typically steady

22
Q

What condition is being seen here? Explain.

A

a fib

lack of coordinate conduction results in no atrial contraction

unsteady rhythm (usually) no discernible P waves

23
Q

What is the condition being seen here? Explain?

A

Wolff- Parkinson-White Syndrome

short PR interval; steady rhythm and normal rate (usually)

slurred upstroke of R wave and widened QRS complex

24
Q

What is Wolff-Parkinson White Syndrome?

A

When there is an accessory pathway to conduction through (Bundle of Kent) between atria and ventricles

the cardiac impulse can travel in retrograde fashion to the atria over accessory pathway and initiate a reentrant tachycardia

25
Q

What are some pathologic conditions associated with elevated ST segment changes?

A

transmural infarct or Prinzmetal angina (coronary vasospasm)

26
Q

What are some pathologic conditions associated with a depressed ST segment?

A

subendocardial ischemia or exertion (stable) angina

27
Q

How does hyperkalemia affect the heart? (How it relates to AP and EKG.

A

increases rate of repolarization resulting sharp spiked T waves and shortened QT interval

28
Q

How does hypokalemia affect the heart? (how it relates to AP and EKG)

A

decreases rate of repolarization resulting in U waves and prolonged QT

29
Q

How does hypercalcemia affect EKG?

A

decreases the QT interval

30
Q

How does hypocalcemia affect EKG?

A

increases the QT interval