Electrical Activity of the Heart Flashcards
(17 cards)
Angina Pectoris
A condition
marked by severe
pain in the chest,
often also
spreading to the
shoulders, arms,
and neck, caused
by an inadequate
blood supply to the
heart (ischemia).
Ischemia affects…
Reduced Blood Flow
Limited ATP available
The sinoatrial node is the
heart’s pacemaker
because it initiates each
wave of excitation known
as
depolarization
A P wave is…
Atrial depolarization
PR interval…
Time between onset of atrial depolarization and ventricular depolarization
QRS complex…
Ventricular depolarization
ST Segment…
Ventricles depolarized (plateau phase)
T wave…
Ventricular repolarization
QT interval…
represents the
time for both ventricular depolarization
and repolarization to occur, duration
ventricular action potential
Ion distribution - where do we find more K?
Inside cell
Ion distribution - where do we find more Na+?
Outside cell
Resting Membrane
Potential [RMP] is
between
-60 and -90 millivolts.
T/F - K+ is highly permeable
T
What do Na+/K+ pumps in myocardial cell membranes do?
Pump 3 Na+ out and 2 K+ in
Depolarization =
Excitation/contraction
Repolarization =
Relaxation/return to rest
Primary Problems of Ischemia
Reduced Blood Flow * Limited ATP Available * Failure of ATP Pumps * K+ Accumulates in Interstitial Fluid * Na+ Moves into Cells (voltage–gated channels) * Resting Membrane Potential Less Negative * Membrane Depolarized, unable to establish RMP