Electrolytes/Biochemistry Flashcards

(31 cards)

1
Q

An elderly diabetic patient is found to have a serum sodium level of 122 and a blood glucose of 30.5. After correcting the glucose concentration with insulin, the serum sodium concentration should:

a) Decrease significantly unless the patient receives 3% saline.

b) Decrease transiently but return to 122 without specific treatment.

c) Remain essentially unchanged.

d) Increase to the normal range without specific therapy.

A

d) Increase to the normal range without specific therapy.

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2
Q

The oxyhemoglobin dissociation curve is shifted to the left by:

a) Decreased blood pH.

b) Increased erythrocyte 2, 3-diphospho – glycerate concentration.

c) Increased body temperature.

d) Methemoglobinemia.

A

Methemoglobinemia.

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3
Q

Harmful effects of significant alkalosis following trauma resuscitation or major surgery include all of the following, EXCEPT:

a) Decreased cerebral blood flow.

b) Hypercalcemia.

c) Hypokalemia.

d) Tissue hypoxia.

A

b) Hypercalcemia.

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4
Q

In the acute-phase response to injury or infection, levels of which of the following serum proteins is decreased?
a) C-reactive protein

b) fibrinogen

c) ceruloplasmin

d) albumin

A

d) albumin

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5
Q

Which of the following can cause spuriously elevated pulse oximeter readings?
a) methemoglobinemia

b) finger nail polish

c) hyperbilirubinemia

d) IV methylene blue

A

A

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6
Q

Stimuli of the neuroendocrine response (3)

A
  1. Hypoxia
  2. Hypotension
  3. Hypovolemia
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7
Q

Where are the baroreceptors located? (3)

A
  1. Atria
  2. Aortic arch
  3. Carotid bodies
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8
Q

What are the effects of cortisol? (2)

A
  1. Gluconeogenesis
  2. Lipolysis
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9
Q

What is the effect of RAS?

A

Increase in aldosterone, increases sodium and water

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10
Q

What is the effect of vasopressin?

A

Increases water resorption in the distal renal tubules

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11
Q

What is the effect of the neuroendocrine response on pancreas?

A

Decreased insulin leading to an increase hepatic gluconeogenesis

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12
Q

In SIRS, what is the organ most sensitive to injury?

A

Lungs, leading to ARDS

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13
Q

What is the most common cause of mortality in the ICU?

A

Multiorgan Dysfunction Syndrome

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14
Q

In hypovolemic shock, what happens to HR, CVP, PCWP, CO, and SVR?

A

HR variable
CVP decreases
PCWP decreases
CO decreases
SVR increases

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15
Q

In NEUROGENIC shock, what happens to HR, CVP, PCWP, CO, and SVR?

A

HR increases
CVP decreases
PCWP decreases
CO decreases
SVR decreases

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16
Q

In CARDIOGENIC shock, what happens to HR, CVP, PCWP, CO, and SVR?

A

HR variable
CVP increases
PCWP increases
CO decreases
SVR increases

17
Q

What percent of blood loss is 750ml? What class of hemorrhagic shock is this?

A

<15%, Class I

18
Q

What percent of blood loss is 750m-1500ml? What class of hemorrhagic shock is this?

A

15-30%, Class II

19
Q

What percent of blood loss is 1500-2000ml? What class of hemorrhagic shock is this?

A

30-40%, Class III

20
Q

What percent of blood loss is > 2000ml? What class of hemorrhagic shock is this?

A

> 40%, Class IV

21
Q

At what class(es) of hemorrhagic shock where you see a BP drop?

A

Class III and Class IV

22
Q

What are the causes of neurogenic shock?

A

Spinal cord injury, regional anesthetic, autonomicle blockade

23
Q

How do you diagnose adrenal insufficiency?

A
  1. Cortisol <15mg/dl
  2. ACTH stimulation test
24
Q

What is the treatment for adrenal insufficiency?

25
What electrolytes are imbalanced after parathyroidectomy?
1. Hypocalcemia 2. Hypomagnasemia 3. Hyperkalemia 4. Hypophosphatemia
26
What is the most common cause of electrolyte disturbance leading to an ileus
Hypokalemia
27
What are the 3 signs and symptoms of central pontine myelinosis
Confusion Spastic quadriplegia Horizontal gaze paralysis
28
What is defined as anuria?
<50cc urine output in 24 hours
29
Oliguria
50 to 400cc urine output in 24 hours
30
What are the indications for acute dialysis?
AEIOU Acidosis Electrolyte abnormalities Intoxication Overload - volume Uremic complication
31